Assessing the Competency of Patients With Alzheimer's Disease Under Different Legal Standards: A Prototype Instrument
Abstract
OBJECTIVE: To assess empirically the competency of patients with Alzheimer's disease (AD) to consent to medical treatment under different legal standards (LSs). DESIGN: Comparison of normal older subjects and patients with AD on measures of competency to consent to medical treatment. SETTING: University medical center. SUBJECTS: Normal older control subjects (n = 15) and patients with probable AD (n = 29 [15 with mild and 14 with moderate AD]). MAIN OUTCOME MEASURES: Two specialized clinical vignettes were developed that test a subject's capacity to consent to medical treatment under five well-established LSs for this competency: LS1, evidencing treatment choice; LS2, making the reasonable choice; LS3, appreciating consequences of choice; LS4, providing rational reasons for choice; and LS5, understanding treatment situation and choices. Performance on the LSs was compared across control and AD groups using Student's t test, chi 2, and analysis of variance. Demented subjects were categorized as competent, marginally competent, or incompetent under each LS by using a cutoff score derived from normal control performance. RESULTS: No differences between groups emerged for LS1 and LS2. Control subjects performed significantly better than patients with mild AD on LS4 and LS5, and significantly better than patients with moderate AD on LS3, LS4, and LS5. Patients with mild AD performed significantly better than patients with moderate AD on LS4 and LS5. With respect to competency status, patients with AD showed a consistent and progressive pattern of compromise (marginal competence or incompetence) related to dementia severity and stringency of the LS. CONCLUSIONS: A reliable prototype instrument validly discriminated the competency performance and classified the competency status of control subjects and patients with mild and moderate AD under five LSs for competency to consent to medical treatment. While the groups performed equivalently on minimal standards requiring merely a treatment choice (LS1) or the reasonable treatment choice (LS2), patients with mild AD had difficulty with more difficult standards requiring rational reasons (LS4) and understanding treatment information (LS5), and patients with moderate AD had difficulty with appreciation of consequences (LS3), rational reasons (LS4), and understanding treatment (LS5). The results raised the concern that many patients with mild AD may not be competent to consent to treatment and supported the value of standardized clinical vignettes for assessment of competency in dementia.
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Certain diseases, medical as well as mental, can affect competence, either temporarily or chronically.
“Furthermore, certain diseases, medical as well as mental, can affect competence, either temporarily (e.g. when a patient loses consciousness) or in a chronical manner (as is the case in progressing Alzheimer’s disease [16]).”
From Medical decision-making in children and adolescents: developmental and neuroscientific aspects (2017) · cites this paper as [16]
The research literature shows consistently that persons even in early stages of dementia are, based on a functional model of capacity, very often or usually incompetent to consent to treatment, to research, or to write an advance treatment directive.
“the research literature that shows consistently that persons even in early stages of dementia are, based on a functional model of capacity, very often or usually incompetent to consent to treatment,(30) to research, (31) or to write an advance treatment directive.(32)”
From Euthanasia and Assisted Suicide of Persons With Dementia in the Netherlands (2020) · cites this paper as [30]
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- Authors
- Marson, D. C.
- Affiliations
- University of Alabama at Birmingham (US)
- Corresponding author
- Marson, Daniel C.
- ORCID
- Marson, Daniel C.
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 1995-10-01
- Volume
- 52
- Issue
- 10
- Pages
- 949
- ISSN
- 0003-9942 (ISSN-L)
- OpenAlex
- W2019211357
- Cited by
- 347
- References
- 28
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 5 · 2023: 4 · 2022: 4 · 2021: 10 · 2020: 10 · 2019: 12 · 2018: 12 · 2017: 21 · 2016: 7 · 2015: 15 · 2014: 11 · 2013: 22 · 2012: 10
- FWCI
- 8.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5p01ag006569-13, 5p30ag010163-05)
- National Institute on Aging (5P01 AG06569-05, 1 P30 AG10163-1)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Healthcare Decision-Making and Restraints
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Keywords
- Alzheimer's disease, capacity to consent, informed consent, dementia severity, clinical vignettes, competency assessment instrument, older adults, clinical decision-making
- MeSH terms
- Aged, Alzheimer Disease, Humans, Informed Consent, Neuropsychological Tests, Mental Competency
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