The relationship between executive functions and capacity to consent to treatment in acute psychiatric hospitalization
Open accessAbstract
Despite the acknowledged influence of cognition on patients' capacity to consent to treatment, the specific neuropsychological domains involved remain elusive, as does the role of executive functions. We investigated possible associations between executive functions and decisional capacity in a sample of acute psychiatric inpatients. Patients were recruited and evaluated through the MacArthur Competence Assessment Tool for Treatment (MacCAT-T), the 24-item Brief Psychiatric Rating Scale (BPRS), the Mini-Mental State Examination (MMSE), and the Wisconsin Card Sorting Test (WCST). Patients with poor executive functioning performed worse in MacCAT understanding, appreciation, and expression of a choice, compared with good performers. These findings point to the importance of cognition in decisional capacity processes. In addition, the strong association found between learning abilities and informed consent decision-making provide empirical evidence indicating possible cognitive enhancement strategies that may improve psychiatric patients' competency.
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Mandarelli, G., Tarsitani, L., Parmigiani, G., Polselli, G. M., Frati, P., Biondi, M., & Ferracuti, S. (2014) · Journal of Forensic Sciences · doi:10.1111/1556-4029.12420 · Cited by 37 · see citing works
Self-citationCapacity to consent to treatment in psychiatry inpatients - a systematic review
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Marcó-García, S., Ariyo, K., Owen, G. S., & David, A. S. (2024) · Psychological Medicine · doi:10.1017/s0033291724000242 · Cited by 18 · see citing works
- Authors
- Mandarelli, G., Parmigiani, G., Tarsitani, L., Frati, P., Biondi, M., & Ferracuti, S.
- Affiliations
- Sapienza University of Rome (IT)
- Corresponding author
- Mandarelli, Gabriele
- ORCID
- Venue
- Journal of Empirical Research on Human Research Ethics
- Publisher
- SAGE Publications
- Published
- 2012-12
- Volume
- 7
- Issue
- 5
- Pages
- 63-70
- ISSN
- 1556-2646 (ISSN-L)
- 1556-2654
- OpenAlex
- W2168851930
- Cited by
- 38
- References
- 47
- Citations by year
- 2025: 2 · 2024: 6 · 2023: 4 · 2022: 1 · 2021: 5 · 2020: 3 · 2019: 6 · 2018: 2 · 2017: 4 · 2016: 1 · 2015: 1 · 2014: 3
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Journal of Empirical Research on Human Research Ethics (publishedVersion)
- PubMed (publishedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Healthcare Decision-Making and Restraints
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Keywords
- executive function, decision-making capacity, informed consent, consent to treatment, acute psychiatric inpatients, cognitive impairment, Wisconsin Card Sorting Test, learning ability, neuropsychological assessment
- MeSH terms
- Adult, Mental Disorders, Cognition, Decision Making, Female, Hospitalization, Humans, Informed Consent, Learning Disabilities, Male, Middle Aged, Mental Competency, Comprehension, Executive Function
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