Effect of some indolealkylamines on man
Abstract
Throughout an arc described by the islands of the Caribbean, the shores of the Amazon, and as far as the western ridges of the Andes, in Colombia and Peru, there has been used since pre-Columbian times a snuff variously known ascohoba, niopo, parica, andyopo, among other designations.1-11With minor variations, this snuff is prepared from seeds of Piptadenia peregrina by grinding with calcined clam shells or wood ashes. It is inhaled or is forcibly blown into the nostrils of the person to be intoxicated by it. Descriptions of the action of the snuff vary somewhat, but the one we have previously reported,12given us by Dr. Jacques Fourcand, is typical. The inhalation of the snuff is quickly followed by rigidity and staring and, at times, a convulsion. This gives way to an excited state, which may last an hour more or less and in which there
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Based on findings of Turner & Merlis (54) that intranasal DMT was pharmacologically inactive, the study did not include a DMT only condition.
“Based on the findings of Turner & Merlis (54) that intranasal DMT was pharmacologically inactive, we did not include a DMT only condition.”
From Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects (2024) · cites this paper as Turner & Merlis (54)
Turner and Merlis conducted a study in the 1950s wherein they found intranasal DMT to be pharmacologically inactive.
“It is noteworthy to mention that Turner and Merlis conducted a study in the 1950s wherein they found intranasal DMT to be pharmacologically inactive (54).”
From Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects (2024) · cites this paper as [54]
Cites
Erspamer, V., & Asero, B. (1952) · Nature · doi:10.1038/169800b0 · Cited by 674 · see citing works
A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS
Woolley, D. W., & Shaw, E. (1954) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.40.4.228 · Cited by 603 · see citing works
SERUM VASOCONSTRICTOR (SEROTONIN)
Rapport, M. M. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)51208-x · Cited by 288 · see citing works
Szára, S. (1956) · Cellular and Molecular Life Sciences · doi:10.1007/bf02157378 · Cited by 203 · see citing works
Henry, T. (1999) · Medical Entomology and Zoology · Cited by 202 · see citing works
Intravenous Bufotenine Injection in the Human Being
Fabing, H. D., & Hawkins, J. (1956) · Science · doi:10.1126/science.123.3203.886 · Cited by 162 · see citing works
Notes of a Botanist on the Amazon & Andes
Wallace, A. R. (2016) · Cited by 129 · see citing works
The Isolation of Bufotenine from Piptadenia peregrina
Stromberg, V. L. (1954) · Journal of the American Chemical Society · doi:10.1021/ja01635a082 · Cited by 86 · see citing works
Effects of Serotonin Antagonists in Normal Subjects and Patients with Carcinoid Tumors
Schneckloth, R. E., Page, I. H., Greco, F., et al. (1957) · Circulation · doi:10.1161/01.cir.16.4.523 · Cited by 75 · see citing works
Alkaloids of Banisteria caapi and Prestonia amazonicum
Hochstein, F. A., & Paradies, A. M. (1957) · Journal of the American Chemical Society · doi:10.1021/ja01578a041 · Cited by 75 · see citing works
ON GOING BERSERK: A NEUROCHEMICAL INQUIRY
Fabing, H. D. (1956) · American Journal of Psychiatry · doi:10.1176/ajp.113.5.409 · Cited by 31 · see citing works
Studies on mescaline I. Action in schizophrenic patients
Denber, H. C. B., & Merlis, S. (1955) · Psychiatric Quarterly · doi:10.1007/bf01567467 · Cited by 30 · see citing works
Phantastica. Narcotic and Stimulating Drugs. Their Use and Abuse
Lewi, N. (1932) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-193205000-00097 · Cited by 29 · see citing works
The Stablemate Concept of Therapy as Affected byLSDin Schizophrenia
Abramson, H. A., Hewitt, M., Lennard, H. L., et al. (1958) · The Journal of Psychology · doi:10.1080/00223980.1958.9916241 · Cited by 20 · see citing works
Argentaffin Carcinoma of Ileum with Raised Serum 5-Hydroxytryptamine
Duncan, D., Garven, J. D., & GIBBONS, J. L. (1955) · BMJ · doi:10.1136/bmj.2.4956.1586 · Cited by 19 · see citing works
STUDIES ON HALLUCINOGENIC SNUFFS
FISH, M. S., & HORNING, E. C. (1956) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-195607000-00004 · Cited by 18 · see citing works
CONCERNING THEORIES OF INDOLES IN SCHIZOPHRENIGENESIS
Turner, W. J., Merlis, S., & Carl, A. (1955) · American Journal of Psychiatry · doi:10.1176/ajp.112.6.466-a · Cited by 10 · see citing works
Self-citationEXPERIENCE WITH “BGE”, A NATURALLY OCCURRING INDOLE COMPOUND
SHERWOOD, W. K. (1957) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-195707000-00028 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Neuropharmacology of N,N-dimethyltryptamine
Carbonaro, T. M., & Gatch, M. B. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.04.016 · Cited by 268 · see citing works
Barker, S. A. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00536 · Cited by 177 · see citing works
Brito-da-Costa, A. M., Dias-da-Silva, D., Gomes, N. G. M., Dinis-Oliveira, R. J., & Madureira-Carvalho, Á. (2020) · Pharmaceuticals · doi:10.3390/ph13110334 · Cited by 117 · see citing works
Barker, S. A. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06065-0 · Cited by 58 · see citing works
Aicher, H. D., Mueller, M. J., Dornbierer, D. A., Suay, D., Elsner, C., Wicki, I., Meling, D., Caflisch, L., Hempe, A., Steinhart, C., et al. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1302559 · Cited by 33 · see citing works
“It is noteworthy to mention that Turner and Merlis conducted a study in the 1950s wherein they found intranasal DMT to be pharmacologically inactive (54).”
BackgroundDornbierer, D. A., Marten, L., Mueller, J., Aicher, H. D., Mueller, M. J., Boxler, M., Kometer, M., Kosanic, D., von Rotz, R., Puchkov, M., et al. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1246892 · Cited by 32 · see citing works
- Authors
- TURNER, W. J.
- Corresponding author
- TURNER, WILLIAM J.
- ORCID
- TURNER, WILLIAM J.
- Venue
- Archives of Neurology And Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1959-01-01
- Volume
- 81
- Issue
- 1
- Pages
- 121
- ISSN
- 0096-6754 (ISSN-L)
- OpenAlex
- W2113331456
- Cited by
- 88
- References
- 18
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 4 · 2018: 2 · 2016: 2 · 2015: 1 · 2014: 1 · 2012: 2
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Neurology And Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Alkaloids: synthesis and pharmacology
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Social Sciences › Psychology › Clinical Psychology › Historical Psychiatry and Medical Practices
- Keywords
- indolealkylamines, hallucinogens, convulsions, excited states, ethnobotany
- MeSH terms
- Antihypertensive Agents, Humans, Indoles, Male, Serotonin, Serotonin Antagonists
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
