The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
The Grading and Prevalence of Macular Degeneration in Chesapeake Bay Watermen
Abstract
A new grading scheme was developed to classify the fundus features of macular degeneration. This scheme identifies the earliest fundus changes associated with macular degeneration, as well as specific drusen characteristics felt to be associated with an increased risk of developing the exudative forms of this disease. Agreement between two graders using this scheme indicated good interobserver reliability. Using this scheme, fundus photographs of 777 participants were graded in a population-based study of watermen from the eastern shore of Maryland. The prevalence of at least one druse within 1500 microns of the foveal center was extremely common (over 80% in each age group over 30 years of age) and not age related. The prevalence of large, confluent, or soft drusen was relatively uncommon and was age related; by the eighth decade, 26% of all participants had large or soft drusen, and 17% of them had confluent drusen. These latter characteristics are more likely to be markers of early changes consistent with age-related macular degeneration rather than simply the presence of a few drusen.
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“Age is the strongest risk factor for age-related macular degeneration; all population-based studies confirm that the prevalence of age-related macular degeneration increases with age in white individuals.3,22–27”
From Age-related macular degeneration (2008) · cites this paper as [26]
Citations
Cites
Statistical Methods for Rates and Proportions
Fleiss, J. L., Levin, B., & Paik, M. C. (2003) · Wiley Series in Probability and Statistics · doi:10.1002/0471445428 · Cited by 18,646
Leibowitz, H. M., Krueger, D. E., Maunder, L. R., Milton, R. C., KINI, M. M., Kahn, H. A., Nickerson, R. J., Pool, J., Colton, T., Ganley, J. P., et al. (1980) · PubMed · Cited by 1,250
Drusen and Disciform Macular Detachment and Degeneration
Gass, J. D. M. (1973) · Archives of Ophthalmology · doi:10.1001/archopht.1973.01000050208006 · Cited by 593
Pathologic Features of Senile Macular Degeneration
GREEN, W. R., McDonnell, P. J., & Yeo, J. H. (2005) · Retina · doi:10.1097/00006982-200507001-00011 · Cited by 315
Cataracts and Macular Degeneration in Older Americans
Klein, R., & Klein, R. (1982) · Archives of Ophthalmology · doi:10.1001/archopht.1982.01030030573002 · Cited by 276
Exposure to Sunlight and Other Risk Factors for Age-Related Macular Degeneration
West, S. K. (1989) · Archives of Ophthalmology · doi:10.1001/archopht.1989.01070010897038 · Cited by 258
DRUSEN AND THEIR RELATIONSHIP TO SENILE MACULAR DEGENERATION
Sarks, S. H. (1980) · Australian and New Zealand Journal of Ophthalmology · doi:10.1111/j.1442-9071.1980.tb01670.x · Cited by 219
Prognosis of Patients with Bilateral Macular Drusen
Smiddy, W. E., & Fine, S. L. (1984) · Ophthalmology · doi:10.1016/s0161-6420(84)34309-3 · Cited by 194
The Prevalence of Macular Drusen in Postmortem Eyes
Coffey, A. J. H., & Brownstein, S. (1986) · American Journal of Ophthalmology · doi:10.1016/0002-9394(86)90138-8 · Cited by 64
Lack of Evidence for Aspirin Use and Prevention of Cataracts
West, S. K., Muñoz, B. E., Newland, H. S., Emmett, E. A., & Taylor, H. R. (1987) · Archives of Ophthalmology · doi:10.1001/archopht.1987.01060090087034 · Cited by 46
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Bird, A. C., Bressler, N. M., Bressler, S. B., Chisholm, I. H., Coscas, G., Davis, M. D., de Jong, P. T. V. M., Klaver, C. C. W., Klein, B. E. K., Klein, R., et al. (1995) · Survey of Ophthalmology · doi:10.1016/s0039-6257(05)80092-x · Cited by 1,926
Self-citationPrevalence of age-related maculopathy
Klein, R., Klein, B. E. K., & Linton, K. L. P. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)31871-8 · Cited by 1,845
Age-related macular degeneration
Jager, R. D., Mieler, W. F., & Miller, J. W. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0801537 · Cited by 1,379
Klein, R., Klein, R., Moss, S. E., & Linton, K. L. P. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)32011-1 · Cited by 1,382
Hageman, G. (2001) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(01)00010-6 · Cited by 1,265
Metadata
- Authors
- Bressler, N. M.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Bressler, Neil M.
- ORCID
- Bressler, Neil M.
- Venue
- Archives of Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 1989-06-01
- Volume
- 107
- Issue
- 6
- Pages
- 847
- ISSN
- 0003-9950 (ISSN-L)
- OpenAlex
- W2081972722
- Cited by
- 251
- References
- 11
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 2 · 2022: 6 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 6 · 2016: 3 · 2015: 5 · 2014: 4 · 2013: 3 · 2012: 11
- FWCI
- 8.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Ophthalmology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Eye Institute (EY-04547)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Retinal Imaging and Analysis
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Keywords
- age-related macular degeneration, drusen, prevalence, watermen, Chesapeake Bay, inter-rater reliability, fundus photography, soft drusen
- MeSH terms
- Adult, Age Factors, Aged, Atrophy, Cross-Sectional Studies, Exudates and Transudates, Humans, Hyperplasia, Macular Degeneration, Male, Maryland, Middle Aged, Ophthalmoscopy, Photography, Pigment Epithelium of Eye, Population Surveillance, Retina, Retinitis Pigmentosa, Risk Factors
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