The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Generalized Anxiety Disorder in Women: A Population-Based Twin Study
Abstract
Little is known about the role of familial and genetic factors in the etiology of generalized anxiety disorder (GAD), a new disorder first proposed in DSM-III. We examine this question in 1033 female-female twin pairs from a population-based registry. Both members in each twin pair were "blindly" assessed by structured psychiatric interview. Our results suggest the following: (1) GAD is a moderately familial disorder; (2) the tendency for GAD to run in families seems to be due largely or entirely to genetic factors shared between relatives rather than to the effects of the familial environment; (3) the heritability of GAD, estimated at around 30%, is modest, with the remainder of the variance in liability resulting from environmental factors not shared by adult twins; (4) the heritability of GAD cannot be explained solely by the occurrence of GAD only during episodes of major depression or panic disorder; and (5) the etiologic role of genetic factors is probably similar in GAD with a 1- vs a 6-month minimum duration of illness.
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Akaike, H. (1987) · Springer Series in Statistics · doi:10.1007/978-1-4612-1694-0_29 · Cited by 4,027
Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia
ROBINS, E., & GUZE, S. B. (1970) · American Journal of Psychiatry · doi:10.1176/ajp.126.7.983 · Cited by 2,243
Cited by
Methodology for Genetic Studies of Twins and Families
Neale, M. C., & Cardon, L. R. (1992) · doi:10.1007/978-94-015-8018-2 · Cited by 4,005
A Review and Meta-Analysis of the Genetic Epidemiology of Anxiety Disorders
Hettema, J. M., Neale, M. C., & Kendler, K. S. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.10.1568 · Cited by 1,563
Self-citationKendler, K. S., Bulik, C. M., Silberg, J., Hettema, J. M., Myers, J., & Prescott, C. A. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.10.953 · Cited by 1,259
Self-citationKendler, K. S., Hettema, J. M., Butera, F., Gardner, C. O., & Prescott, C. A. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.8.789 · Cited by 966
Self-citationDSM-III-R Generalized Anxiety Disorder in the National Comorbidity Survey
Wittchen, H.-U. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950050015002 · Cited by 967
Metadata
- Authors
- Kendler, K. S.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1992-04-01
- Volume
- 49
- Issue
- 4
- Pages
- 267
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2054298209
- Cited by
- 276
- References
- 2
- FWCI
- 20.60
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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