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Cited by 276

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Generalized Anxiety Disorder in Women: A Population-Based Twin Study

Kendler, Kenneth S.·1992·Archives of General Psychiatry
DOI 10.1001/archpsyc.1992.01820040019002
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Abstract

Little is known about the role of familial and genetic factors in the etiology of generalized anxiety disorder (GAD), a new disorder first proposed in DSM-III. We examine this question in 1033 female-female twin pairs from a population-based registry. Both members in each twin pair were "blindly" assessed by structured psychiatric interview. Our results suggest the following: (1) GAD is a moderately familial disorder; (2) the tendency for GAD to run in families seems to be due largely or entirely to genetic factors shared between relatives rather than to the effects of the familial environment; (3) the heritability of GAD, estimated at around 30%, is modest, with the remainder of the variance in liability resulting from environmental factors not shared by adult twins; (4) the heritability of GAD cannot be explained solely by the occurrence of GAD only during episodes of major depression or panic disorder; and (5) the etiologic role of genetic factors is probably similar in GAD with a 1- vs a 6-month minimum duration of illness.

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Metadata

Authors
Kendler, K. S.
Venue
Archives of General Psychiatry
Publisher
American Medical Association (AMA)
Published
1992-04-01
Volume
49
Issue
4
Pages
267
ISSN
0003-990X (ISSN-L)
DOI
10.1001/archpsyc.1992.01820040019002
OpenAlex
W2054298209
Cited by
276
References
2
FWCI
20.60
Type
journal article
Language
en
Open access
closed

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