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Physiologic Responses to Loud Tones in Israeli Patients With Posttraumatic Stress Disorder
Abstract
Orbicularis oculi (eye blink) electromyogram, skin conductance, and heart rate responses to 15 consecutive 95-dB, 500-millisecond, 1000-Hz tones with 0-millisecond rise and fall times were measured in 14 patients with posttraumatic stress disorder, 14 patients with other anxiety disorders, 15 mentally healthy subjects with past traumatic experiences, and 19 mentally healthy subjects with no trauma history. The patients with posttraumatic stress disorder showed significantly larger skin conductance and heart rate responses and a trend toward larger electromyogram responses to the tones than every other group. These effects were not explained by subjective anxiety, resting physiologic arousal, physiologic arousal preceding the tone trials, or initial physiologic responsivity. The group with posttraumatic stress disorder was the only one that failed to show habituation of skin conductance responses.
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“Enhanced ASR and HPA-negative feedback have been reliably observed in patients with PTSD (Shalev et al, 1992;Yehuda et al, 1993;Orr et al, 1997).”
From Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress (2012) · cites this paper as Shalev et al, 1992
In the citing paper
“Enhanced ASR and HPA-negative feedback have been reliably observed in patients with PTSD (Shalev et al, 1992;Yehuda et al, 1993;Orr et al, 1997).”
From Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress (2012) · cites this paper as Shalev et al, 1992
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Metadata
- Authors
- Shalev, A. Y.
- Affiliations
- Hadassah Medical Center (IL)
- Corresponding author
- Shalev, Arieh Y.
- ORCID
- Shalev, Arieh Y.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1992-11-01
- Volume
- 49
- Issue
- 11
- Pages
- 870
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2040357544
- Cited by
- 236
- References
- 37
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 8 · 2015: 5 · 2014: 4 · 2013: 9 · 2012: 3
- FWCI
- 8.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- post-traumatic stress disorder, skin conductance, heart rate, blinking, anxiety disorders, habituation, autonomic arousal, trauma history
- MeSH terms
- Acoustic Stimulation, Adult, Anxiety Disorders, Arousal, Blinking, Diagnosis, Differential, Female, Galvanic Skin Response, Habituation, Psychophysiologic, Heart Rate, Humans, Life Change Events, Male, Reflex, Startle, Stress Disorders, Post-Traumatic
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