The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
The Neurobiology of Sexual Function
Abstract
This article provides a review of the past and current literature on the neurobiology of sexual function. The influence of endocrine, neurotransmitter, and central nervous system influences on male and female sexual function are discussed for sexual desire, arousal, and orgasm or ejaculation stages of sexual responding. Endocrine factors reviewed include the following: androgens, estrogens, progesterone, prolactin, oxytocin, cortisol, and pheromones. Neurotransmitters and neuropeptides discussed include nitric oxide, serotonin, dopamine, epinephrine, norepinephrine, opioids, acetylcholine, histamine, and gamma-aminobutyric acid. Central nervous system influences on sexual function are discussed briefly with reference to brainstem regions, the hypothalamus, and the forebrain.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Oral Sildenafil in the Treatment of Erectile Dysfunction
Goldstein, I., Lue, T. F., Padma-Nathan, H., Rosen, R. C., Steers, W. D., & Wicker, P. A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199805143382001 · Cited by 2,120
Plasma oxytocin increases in the human sexual response
CARMICHAEL, M. S., HUMBERT, R., DIXEN, J., PALMISANO, G., GREENLEAF, W., & DAVIDSON, J. M. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-1-27 · Cited by 554 · cited 1×
“During sexual arousal and orgasm, oxytocin from the paraventricular nucleus is secreted from the posterior pituitary into the blood stream in both sexes.(279,280) As noted earlier, oxytocin injected into the CNS activates penile erections.”
BackgroundMontejo-gonzàlez, A. L., Llorca, G., Izquierdo, J. A., Ledesma, A., Bousono, M., Calcedo, A., Carrasco, J. L., Ciudad, J., Daniel, E., De LA Gandara, J., et al. (1997) · Journal of Sex & Marital Therapy · doi:10.1080/00926239708403923 · Cited by 505 · cited 1×
“A prospective study examining 344 male and female outpatients found that SSRI-induced sexual dysfunction was more severe in women than in men.(155) Animal studies have conflicting findings with some studies reporting that serotonin antagonists and agonists inhibit lordosis in female rats(177-182) while others report t…”
ResultKWAN, M., GREENLEAF, W. J., MANN, J., CRAPO, L., & DAVIDSON, J. M. (1983) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-57-3-557 · Cited by 339
Changes in oxytocin and vasopressin secretion during sexual activity in men
MURPHY, M. R., SECKL, J. R., BURTON, S., CHECKLEY, S. A., & LIGHTMAN, S. L. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-65-4-738 · Cited by 318
Turner, R. A., Altemus, M., Enos, T., Cooper, B., & McGuinness, T. (1999) · Psychiatry · doi:10.1080/00332747.1999.11024859 · Cited by 298
Böös, J. N., von Schoultz, B., & Carlström, K. (1993) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.3109/01674829309084451 · Cited by 188
The role of oxytocin in relation to female sexual arousal
Blaicher, W., Gruber, D., Bieglmayer, C., Blaicher, A. M., Knogler, W., & Huber, J. C. (1999) · Gynecologic and Obstetric Investigation · doi:10.1159/000010075 · Cited by 186
Bancroft, J., Tennent, G., Loucas, K., & Cass, J. (1974) · British Journal of Psychiatry · doi:10.1192/bjp.125.3.310 · Cited by 181
Cardiovascular and Endocrine Alterations After Masturbation-Induced Orgasm in Women
Exton, M. S., Bindert, A., Kruger, T., Scheller, F., Hartmann, U., & Schedlowski, M. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199905000-00005 · Cited by 174
Cited by
Hypersexual disorder: A proposed diagnosis for DSM-V
Kafka, M. P. (2010) · Archives of Sexual Behavior · doi:10.1007/s10508-009-9574-7 · Cited by 1,095
Baumeister, R. F., Catanese, K. R., & Vohs, K. D. (2001) · Personality and Social Psychology Review · doi:10.1207/s15327957pspr0503_5 · Cited by 862
Ecological effects of pharmaceuticals in aquatic systems—impacts through behavioural alterations
Brodin, T., Piovano, S., Fick, J., Klaminder, J., Heynen, M., & Jonsson, M. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2013.0580 · Cited by 499
Chivers, M. L., Seto, M. C., & Blanchard, R. (2007) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.93.6.1108 · Cited by 284
The Nature of Sexual Desire: A Clinician's Perspective
Levine, S. B. (2003) · Archives of Sexual Behavior · doi:10.1023/a:1023421819465 · Cited by 280
Metadata
- Authors
- Meston, C. M., & Frohlich, P. F.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2000-11-01
- Volume
- 57
- Issue
- 11
- Pages
- 1012
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2100775336
- Cited by
- 446
- References
- 15
- FWCI
- 12.03
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Neurobiology of Sexual Function. https://app.cochat.ai/papers/10.1001/archpsyc.57.11.1012
- The paper
- Meston, C. M., & Frohlich, P. F. (2000). The Neurobiology of Sexual Function. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.57.11.1012
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
