Alternative Splicing, Methylation State, and Expression Profile of Tropomyosin-Related Kinase B in the Frontal Cortex of Suicide Completers

Ernst, Carl, Deleva, Vesselina, Deng, Xiaoming, Sequeira, Adolfo, Pomarenski, Amanda, Klempan, Tim, Ernst, Neil, Quirion, Remi, Gratton, Alain, Szyf, Moshe, Turecki, Gustavo·2009·Archives of General Psychiatry
DOI 10.1001/archpsyc.66.1.22

Cited by (234)

Items 101–200 of 234

  1. Effect of Maternal Stress Prior to Conception on Hippocampal BDNF Signaling in Rat Offspring
    Somayeh Niknazar, Arezo Nahavandi, Ali Asghar Peyvandi, Hassan Peyvandi, Fatemeh Zare Mehrjerdi, Mohsen Karimi · 2016 · Molecular Neurobiology
  2. Transgenerational Abnormalities Induced by Paternal Preconceptual Alcohol Drinking: Findings from Humans and Animal Models
    Sergio Amedeo Terracina, Giampiero Ferraguti, Luigi Tarani, Marisa Patrizia Messina, Marco Lucarelli, Mario Vitali, Simone De Persis, Antonio Greco, Antonio Minni, Antonella Polimeni et al. · 2021 · Current Neuropharmacology
  3. Genetics and epigenetics of self‐injurious thoughts and behaviors: Systematic review of the suicide literature and methodological considerations
    Salahudeen A. Mirza, Anna R. Docherty, Amanda V. Bakian, Hilary H Coon, Jair C. Soares, Consuelo Walss‐Bass, Gabriel R. Fries · 2022 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  4. Tyrosine kinase B protein expression is reduced in the cerebellum of patients with bipolar disorder
    Benchawanna Soontornniyomkij, Ian Everall, Gursharan Chana, Ming T. Tsuang, Cristian L. Achim, Virawudh Soontornniyomkij · 2011 · Journal of Affective Disorders
  5. - Brain-Derived Neurotrophic Factor in Suicide Pathophysiology
    Yogesh Dwivedi · 2012 · CRC Press eBooks
  6. Epigenetic modifications associated with suicide and common mood and anxiety disorders: a systematic review of the literature
    Abdulrahman M. El‐Sayed, M. Haloossim, Sandro Galea, Karestan Chase Koenen · 2012 · Biology of Mood & Anxiety Disorders
  7. Proteomic Investigation of Epigenetics in Neuropsychiatric Disorders: A Missing Link between Genetics and Behavior?
    Mariana D. Plazas-Mayorca, Kent E. Vrana · 2010 · Journal of Proteome Research
  8. A Deletion in Tropomyosin-Related Kinase B and the Development of Human Anxiety
    Carl Ernst, Brigitte Wanner, Jelena Brezo, Frank Vitaro, Richard Ernest Tremblay, Gustavo Turecki · 2010 · Biological Psychiatry
  9. Association study of early-immediate genes in childhood-onset mood disorders and suicide attempt
    John Strauss, Stuart McGregor, Natalie Freeman, Arun Kumar Tiwari, Charles J. George, Mária Kovács, James L. Kennedy · 2012 · Psychiatry Research
  10. Epigenetic Mechanisms of Rapid-Acting Antidepressants
    Inserra, Antonio, Campanale, Antonella, Rezai, Tamim, Romualdi, Patrizia, Rubino, Tiziana · 2024 · Translational Psychiatry
  11. DNA methylation in stress and depression: from biomarker to therapeutics
    Amanda J. Sales, Francisco Silveira Guimarães, Sâmia R.L. Joca · 2021 · Acta Neuropsychiatrica
  12. RNA and neuronal function: the importance of post-transcriptional regulation
    Vandita D Bhat, Jagannath Jayaraj, Kavita Babu · 2022 · Oxford Open Neuroscience
  13. Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
    Daniil Sarkisyan, Muhammad Zubair Hussain, Hiroyuki Watanabe, Olga Kononenko, Igor Bazov, Xingwu Zhou, О. V. Yamskova, Oleg Krishtal, Victor M. Karpyak, Tatiana Yakovleva et al. · 2015 · Frontiers in Cellular Neuroscience
  14. Multimarker analysis suggests the involvement of BDNF signaling and microRNA biosynthesis in suicidal behavior
    Attila József Pulay, János Réthelyi · 2016 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  15. Glucocorticoid regulates TrkB protein levels via c-Cbl dependent ubiquitination: A decrease in c-Cbl mRNA in the prefrontal cortex of suicide subjects
    Chirayu D. Pandya, Ammar Kutiyanawalla, Gustavo Turecki, Anilkumar Pillai · 2014 · Psychoneuroendocrinology
  16. Cortical neurons from intrauterine growth retardation rats exhibit lower response to neurotrophin BDNF
    Midori Ninomiya, Tadahiro Numakawa, Naoki Adachi, Miyako Furuta, Shuichi Chiba, Misty Richards, Shigenobu Shibata, Hiroshi Kunugi · 2010 · Neuroscience Letters
  17. Epigenetic Alterations of Brain Non-Neuronal Cells in Major Mental Diseases
    Hamid M. Abdolmaleky, Marian Martin, Jin‐Rong Zhou, Sam Thiagalingam · 2023 · Genes
  18. Broadening our horizons: Gene expression profiling to help better understand the neurobiology of suicide and depression
    Laura M. Fiori, Gustavo Turecki · 2010 · Neurobiology of Disease
  19. Epigenetic studies of suicidal behavior
    Ali Bani‐Fatemi, Aaron S. Howe, Vincenzo De Luca · 2014 · Neurocase
  20. The role of brain-derived neurotrophic factor in the pathophysiology of suicidal behavior.
    Alja Videtič Paska, Tomaž Zupanc, Peter Pregelj · 2013 · PubMed
  21. Postmortem brain tissue as an underutilized resource to study the molecular pathology of neuropsychiatric disorders across different ethnic populations
    Eric Vornholt, Dan Luo, Wenying Qiu, Gowon O. McMichael, Yangyang Liu, Nathan A. Gillespie, Chao Ma, Vladimir I. Vladimirov · 2019 · Neuroscience & Biobehavioral Reviews
  22. Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity
    Suzana Ulian-Benitez, Simon Bishop, István Földi, Jill S. Wentzell, Chinenye Okenwa, Manuel G. Forero, Bangfu Zhu, Marta Moreira, Mark Phizacklea, Graham McIlroy et al. · 2017 · PLoS Genetics
  23. Suicide and Neurotrophin Factors: A Systematic Review of the Correlation between BDNF and GDNF and Self-Killing
    Stefania De Simone, Maria Antonella Bosco, Raffaele La Russa, Simona Vittorio, Nicola Di Fazio, Margherita Neri, Luigi Cipolloni, Benedetta Baldari · 2022 · Healthcare
  24. How to save a life: From neurobiological underpinnings to psychopharmacotherapies in the prevention of suicide
    Xénia Gonda, Péter Döme, Gianluca Serafini, Maurizio Pompili · 2023 · Pharmacology & Therapeutics
  25. Brain derived neurotrophic factor (BDNF) and suicidal behavior: A review of studies from Asian countries.
    A. Sonal, V. Raghavan · 2018 · Asian Journal of Psychiatry
  26. Gene expression profiling of suicide completers
    Laura M. Fiori, Gustavo Turecki · 2010 · European Psychiatry
  27. Endophenotypes as a measure of suicidality
    Dimitry A. Chistiakov, Zurab I. Kekelidze, Vladimir Pavlovich Chekhonin · 2012 · Journal of Applied Genetics
  28. Evaluation of postmortem cerebrospinal fluid S100B protein and serotonin levels: comparison of suicidal versus nonsuicidal deaths in Konya, Turkey
    Dogan, Kamil Hakan, Unaldi, Mustafa, Demirci, Serafettin · 2016 · Journal of Forensic Sciences
  29. Understanding the Neuroepigenetic Constituents of Suicide Brain
    Roy, Bhaskar, Dwivedi, Yogesh · 2018 · Progress in Molecular Biology and Translational Science
  30. Glial Markers of Suicidal Behavior in the Human Brain—A Systematic Review of Postmortem Studies
    Mana Yamamoto, Mai Sakai, Zhiqian Yu, Miharu Nakanishi, Hatsumi Yoshii · 2024 · International Journal of Molecular Sciences
  31. Changes in cortical protein markers of iron transport with gender, major depressive disorder and suicide
    Brian Dean, Andrew Tsatsanis, Linh Q. Lam, Elizabeth Scarr, James A. Duce · 2018 · The World Journal of Biological Psychiatry
  32. Proteomic profiling of postmortem prefrontal cortex tissue of suicide completers
    Min Ji Kim, Misol Do, Dohyun Han, Minsoo Son, Dongyoon Shin, Injoon Yeo, Young Hyun Yun, Seong Ho Yoo, Hyung Jin Choi, Daun Shin et al. · 2022 · Translational Psychiatry
  33. Molecular Changes Associated with Suicide
    Daniela Navarro, Marta Marín, Ani Gasparyan, María S. García‐Gutiérrez, Gabriel Rubio, Jorge Manzanares · 2023 · International Journal of Molecular Sciences
  34. Genome-wide methylome-based molecular pathologies associated with depression and suicide
    Yogesh Dwivedi, Bhaskar Roy, Praveen Kumar Korla · 2024 · Neuropsychopharmacology
  35. Modeling endophenotypes of suicidal behavior in animals
    Bhaskar Roy, Yogesh Dwivedi · 2021 · Neuroscience & Biobehavioral Reviews
  36. Methyl- and acetyltransferases are stable epigenetic markers postmortem
    Camelia Maria Monoranu, Edna Grünblatt, Jasmin Bartl, Andrea Hans Meyer, Manuela Apfelbacher, Daniela Barbara Keller, Tanja Maria Michel, Safa Al‐Saraj, Andrea Schmitt, Peter Falkai et al. · 2010 · Cell and Tissue Banking
  37. Epigenetic Effects of Childhood Adversity in the Brain and Suicide Risk
    Yogesh Dwivedi · 2012 · CRC Press eBooks
  38. The potential of microRNAs as putative biomarkers in major depressive disorder and suicidal behavior
    Gianluca Serafini, Alice Trabucco, Giovanni Pietro Corsini, Andrea Escelsior, Andrea Amerio, Andrea Aguglia, Henry A. Nasrallah, Mario Amore · 2021 · Biomarkers in Neuropsychiatry
  39. Who's Afraid of Anxiety Genetics?
    Jordan W. Smoller · 2011 · Biological Psychiatry
  40. Gene Expression Analysis in Postmortem Brains from Individuals Who Died by Suicide: A Systematic Review
    Thelma Beatriz González‐Castro, Alma Delia Genis Mendoza, María Lilia López‐Narváez, Isela Esther Juárez‐Rojop, Miguel Ángel Ramos-Méndez, Carlos Alfonso Tovilla‐Zárate, Humberto Nicolini · 2023 · Brain Sciences
  41. Genes, cognition, and social behavior: Next steps for foundations and researchers
    Arthur Lupia · 2011 · Politics and the Life Sciences
  42. Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results
    Brenda Cabrera‐Mendoza, José Jaime Martínez‐Magaña, Alma Delia Genis Mendoza, Nancy Monroy‐Jaramillo, Consuelo Walss‐Bass, Gabriel R. Fries, Fernando García‐Dolores, Mauro López‐Armenta, Gonzalo Flores, Rubén Antonio Vázquez‐Roque et al. · 2020 · Revista de investigaci�n Cl�nica
  43. MicroRNAs: fundamental regulators of gene expression in major affective disorders and suicidal behavior?
    Gianluca Serafini, Maurizio Pompili, Katelin F. Hansen, Karl H. Obrietan, Yogesh Dwivedi, Mario Amore, Noam Shomron, Paolo Girardi · 2013 · Frontiers in Cellular Neuroscience
  44. Connecting the emotional-cognitive puzzle: The role of tyrosine kinase B (TrkB) receptor isoform imbalance in age-related emotional and cognitive impairments
    Noa Bregman-Yemini, Keren Nitzan, Motty Franko, Ravid Doron · 2024 · Ageing Research Reviews
  45. From trauma to depression: structural, synaptic, epigenetic, and molecular pathways linking early stress to lifelong vulnerability
    Mina Takahashi, Richard Charles Shelton · 2025 · Frontiers in Psychiatry
  46. A Glimpse Into the Sexual Dimorphisms in Major Depressive Disorder Through Epigenetic Studies
    Branden Cahill, Samuel Poelker-Wells, Jonathan F. Prather, Yun Li · 2021 · Frontiers in Neural Circuits
  47. Epigenetic studies in suicidal ideation and behavior
    Oluwagbenga O. Dada, Jessica Qian, Nzaar Al-Chalabi, Nathan J. Kolla, Ariel Graff, Clement C.H. Zai, Philip Gerretsen, Vincenzo De Luca · 2021 · Psychiatric Genetics
  48. Working Memory and Response Inhibition in Patients With Bipolar I Disorder During Euthymic Period
    Zahra Farahmand, Mehdi Tehrani‐Doost, Homayoun Amini‎, Abolfazl Mohammadi, Mosleh Mirzaei, Azar Mohammadzadeh · 2015 · Iranian Journal of Psychiatry and Behavioral Sciences
  49. SNAT1 and a family with high rates of suicidal behavior
    Carl Ernst, Peter C. Dumoulin, Sophie Cabot, Jeffrey D. Erickson, Gustavo Turecki · 2009 · Neuroscience
  50. The Role of Epigenetic Dysregulation in Suicidal Behaviors
    Laura M. Fiori, Gustavo Turecki · 2020 · Current topics in behavioral neurosciences
  51. Transgenerational Abnormalities Induced by Paternal Preconceptual Alcohol Drinking: Findings from Humans and Animal Models
    2022 · Current Neuropharmacology
  52. Impairments in Brain-Derived Neurotrophic Factor-Induced Glutamate Release in Cultured Cortical Neurons Derived from Rats with Intrauterine Growth Retardation: Possible Involvement of Suppression of TrkB/Phospholipase C-γ Activation
    Tadahiro Numakawa, Tomoya Matsumoto, Yoshiko Ooshima, Shuichi Chiba, Miyako Furuta, Aiko Izumi, Midori Ninomiya, Haruki Odaka, Kazuo Hashido, Naoki Adachi et al. · 2014 · Neurochemical Research
  53. Putting the ‘epi’ into epigenetics research in psychiatry
    Abdulrahman M. El‐Sayed, Karestan Chase Koenen, Sandro Galea · 2013 · Journal of Epidemiology & Community Health
  54. Suicidal Behavior: A Distinct Psychobiology?
    Naji C. Salloum · 2017 · American Journal of Psychiatry Residents Journal
  55. Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk
    Zsüliet Kristóf, Zsófia Gál, Dóra Török, Nóra Eszlári, Sára Sütöri, Beáta Sperlágh, Ian Muir Anderson, J.F.W. Deakin, György Bagdy, Gabriella Juhász et al. · 2024 · International Journal of Molecular Sciences
  56. Co-Regulation and Epigenetic Dysregulation in Schizophrenia and Bipolar Disorder
    Dóra Zelena · 2012 · Springer eBooks
  57. Tropomyosin-related kinase B receptor polymorphisms and isoforms expression in suicide victims
    Federica Zarrilli, Felice Amato, Simona Keller, Ermanno Florio, Vladimir Carli, Liborio Stuppia, Marco Sarchiapone, Lorenzo Chiariotti, Giuseppe Castaldo, Rossella Tomaiuolo · 2014 · Psychiatry Research
  58. Major Depressive Disorder' Definition, Etiology and Epidemiology: A Review -
    Fatmagül Helvacı Çelik, Çiçek Hocaoğlu · 2016 · DergiPark (Istanbul University)
  59. Research on potential biomarker correlates for suicidal behavior: A review
    Sangha Kim, Kyoung‐Uk Lee · 2017 · Asia-Pacific Psychiatry
  60. Neuron and astrocyte specific 5mC and 5hmC signatures of BDNF’s receptor, TrkB
    Xiaoran Wei, Jack L. Browning, Michelle Lynne Olsen · 2024 · Frontiers in Molecular Neuroscience
  61. The Epigenetics of Depression and Suicide
    Benoît Labonté, Gustavo Turecki · 2011 · Springer eBooks
  62. Épigénétique : un lien entre l’environnement et le génome
    Benoît Labonté, Gustavo Turecki · 2013 · Santé mentale au Québec
  63. Epigenetic marks in suicide: a review
    Daniel Francisco Ramos-Rosales, Fernando Vázquez-Alaníz, Norma Urtiz-Estrada, Eda G. Ramirez-Valles, Edna Madai Méndez-Hernández, Alma Cristina Salas-Leal, Marcelo Barraza-Salas · 2021 · Psychiatric Genetics
  64. Approaches and Findings from Gene Expression Profiling Studies of Suicide
    Laura M. Fiori, Gustavo Turecki · 2012
  65. GENOME-WIDE DNA METHYLATION PATTERNS IN SUICIDE VICTIMS: IDENTIFICATION OF NEW CANDIDATE GENES
    Katarina Kouter, Tomaž Zupanc, Alja Videtič Paska · 2019 · Psychiatria Danubina
  66. Epigenetische Mechanismen der Depression
    Georgios Paslakis, Stefan Bleich, Helge Frieling, Michael Deuschle · 2011 · Der Nervenarzt
  67. Associations between DNA methylation of Promoter Exon IX, Serum Protein and mRNA levels of Brain-derived Neurotrophic factor in Patients with Bipolar Mania
    Chin Chuen Lin, Yi Yung Hung, Tiao Lai Huang · 2018 · Neuropsychiatry
  68. Stress Responsiveness of BDNF/TrkB Signaling in the Neuroendocrine System and Future Implications
    Idu Azogu‐Sepe, Hélène Plamondon · 2020 · Elsevier eBooks
  69. Deciphering the Epigenetic Landscape of Suicidal Behaviour: A Review of Current Findings, Caveats and Future Directions
    Stefania S S Policicchio, Emma Louise Dempster, Therese M. Murphy · 2018 · OBM Genetics
  70. A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
    Jun Sun, Francisca Rojo-Cortés, Suzana Ulian-Benitez, Manuel G. Forero, Guiyi Li, Deepanshu ND Singh, Xiaocui Wang, Sebastian Cachero, Marta Moreira, Dean Philip John Kavanagh et al. · 2024 · eLife
  71. Social Environment and DNA Methylation: A Mechanism for Linking Nurture and Nature
    Moshe Szyf A · 2013 · Epigenetics and human health
  72. Impact of the Early-Life Environment on the Epigenome and Behavioral Development
    Benoît Labonté, Gustavo Turecki · 2013 · Springer eBooks
  73. Epigenetics of Suicidal Behaviour
    Gustavo Turecki · 2015 · Advances in biological psychiatry
  74. Early-Life Adversity and Epigenetic Changes
    Benoît Labonté, Adel Farah, Gustavo Turecki · 2015 · Cambridge University Press eBooks
  75. Epigenetic effects of childhood abuse on the human brain
    Benoît Labonté, Gustavo Turecki · 2012 · Cambridge University Press eBooks
  76. The epigenetics of suicide: The critical impact of environment on epigenetic regulation in suicide
    Pierre-Éric Lutz, Gustavo Turecki, Benoît Labonté · 2021 · Elsevier eBooks
  77. Neurobiological understanding of suicide
    Sanghak Kim, Kyoung-Uk Lee · 2019 · Journal of Korean Medical Association
  78. Mechanistic convergence of depression and suicidality on astrocyte fatty acid metabolism
    Eamon Fitzgerald, Nicholas O’Toole, Irina Pokhvisneva, Gustavo Turecki, Corina Nagy, Michael Joseph Meaney · 2023 · medRxiv
  79. Astrocyte fatty acid metabolism as a driver of risk for major depressive disorder
    Eamon Fitzgerald, Nicholas O’Toole, Irina Pokhvisneva, Eric J. Nestler, Gustavo Turecki, Corina Nagy, Michael Joseph Meaney · 2026 · Nature Communications
  80. Genetics and Genomics of Posttraumatic Stress Disorder
    Monica Uddin, Ananda B. Amstadter, Nicole R. Nugent, Karestan Chase Koenen · 2012 · Oxford University Press eBooks
  81. DNA Methylation and Epigenetic Biomarkers in Non-Neoplastic Diseases
    Michel Neidhart · 2015 · Elsevier eBooks
  82. Epidemiology, Epigenetics, and Psychopathology
    Angela C. Bustamante, Monica Uddin · 2014 · Medical Epigenetics
  83. Brain Networks, Hormones and Genes Implicated in Depression
    Maxwell R. Bennett · 2012 · Springer eBooks
  84. 12 Heredity in the Epigenetic Era: Are We Facing a Politics of Reproductive Obligations?
    Michael Crawford · 2016 · BRILL eBooks
  85. An Epigenetic View of Suicide and Early Life Adversity
    Dave Checknita, Benoît Labonté, Gustavo Turecki · 2012 · Psychiatric Annals
  86. NEUROBIOLOGICAL ASPECTS OF SUICIDE AND SUICIDE ATTEMPTS IN BIPOLAR DISORDER Experimental Therapeutics
    Pathophysiology Branch, Daniel C. Mathews, Erica M. Richards, Mark J. Niciu, Dawn Flosnik Ionescu, Joseph J. Rasimas, Carlos A. Zarate · 2013
  87. 19 Epigenetic adaptation during early life
    Moshe Szyf A · 2011 · De Gruyter eBooks
  88. The Epigenetics of Suicide
    Benoît Labonté, Pierre-Éric Lutz, Gustavo Turecki · 2014 · Elsevier eBooks
  89. Chapter 15 – The Epigenetics of Suicide: The Critical Impact of the Environment on Epigenetic Regulation in Suicide
    Benoît Labonté, Pierre-Éric Lutz, Gustavo Turecki · 2014 · Academic Press eBooks
  90. Recent Progress in Functional Genomic Studies of Depression and Suicide
    Daniel Medeiros Almeida, Gustavo Turecki · 2017 · Current Genetic Medicine Reports
  91. Gene-Environment Interactions and Role of Epigenetics in Depression
    Eugene Lin, Shih‐Jen Tsai · 2017 · Springer eBooks
  92. Chromatin-Based Treatments for Affective Disorders – Insight or Utopia
    Herbert E. Covington, Olivier Berton · 2010 · Modern trends in psychiatry
  93. Zelfmoord
    Frans Sluyter · 2010 · Neuropraxis
  94. A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
    Jun Sun, Francisca Rojo-Cortés, Suzana Ulian-Benitez, Manuel G. Forero, Guiyi Li, Deepanshu ND Singh, Xiaocui Wang, Sebastian Cachero, Marta Moreira, Dean Philip John Kavanagh et al. · 2024 · eLife
  95. Epigenetic involvement in psychiatric disorders and psychiatric drugs
    Noëlle M. de Jong · 2010 · Utrecht University Repository (Utrecht University)
  96. Epigenetic Epidemiology of Psychiatric Disorders
    Monica Uddin, Angela C. Bustamante, Satoshi Toyokawa · 2014 · Elsevier eBooks
  97. Receptor signaling in suicide
    Yogesh Dwivedi · 2014 · Cambridge University Press eBooks
  98. Ce que la microscopie peut nous apprendre sur le suicide
    Naguib Mechawar · 2013 · Santé mentale au Québec
  99. A role for astroctye-related genes in suicide
    Carl Ernst · 2009
  100. Epigenetics
    Benoît Labonté, Gustavo Turecki · 2014 · Cambridge University Press eBooks