Type D Personality and Mortality in Peripheral Arterial Disease: A Pilot Study
Abstract
BACKGROUND: Type D personality refers to the tendency to experience negative emotions and to inhibit self-expression in social interaction and has been shown to be an independent predictor of mortality in cardiac disease. Information about the effects of psychological traits on prognosis is lacking in cases of peripheral arterial disease (PAD). OBJECTIVE: To examine whether type D personality predicts all-cause mortality in PAD. DESIGN: Pilot follow-up study. SETTING: Vascular surgery department of a teaching hospital. PATIENTS: A total of 184 patients with symptomatic PAD (mean [SD] age, 64.8 [9.8] years) were followed up for 4 years (interquartile range, 3.5-4.5 years). MAIN OUTCOME MEASURES: Patients completed the type D Scale-14 measure of type D personality at baseline. Information about all-cause mortality was obtained from patient medical files. RESULTS: During 4-year follow-up, 16 patients (8.7%) died. Adjusting for age and sex, type D personality was predictive of mortality (P = .03). Ankle-brachial index (P = .05), age (P = .009), diabetes mellitus (P = .02), pulmonary disease (P = .09), and renal disease (P = .02) were also predictive of mortality. Multivariable logistic regression revealed that age, diabetes, and renal disease were independent predictors of all-cause mortality (odds ratios, 1.1-2.3). After adjustment for these clinical predictors, patients with type D personality still had a more than 3-fold increased risk of death (odds ratio, 3.5; 95% confidence interval, 1.1-11.1; P = .04). CONCLUSIONS: Type D personality predicts an increased risk of all-cause mortality in PAD, above and beyond traditional risk factors. Further research is needed to confirm these findings, but this pilot study suggests that the assessment of type D personality may be useful for detecting high-risk patients with PAD.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Type D increases risk of mortality over 4 years in peripheral artery disease patients who underwent vascular surgery.
“over 4 years in peripheral artery disease (PAD) patients who underwent vascular surgery [142]”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [142]
Type D increases risk of mortality over 2.5 years in patients with chronic heart failure.
“over 2.5 years in patients with chronic heart failure (CHF) [141]”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [141]
Cites
Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)
Norgren, L., Hiatt, W. R., Dormandy, J. A., Nehler, M. R., Harris, K. A., & Fowkes, F. G. R. (2007) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2006.12.037 · Cited by 8,191 · see citing works
Recommended standards for reports dealing with lower extremity ischemia: Revised version
Rutherford, R. B., Baker, J. D., Ernst, C. B., Johnston, K. W., Porter, J. M., Ahn, S. S., & Jones, D. N. (1997) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(97)70045-4 · Cited by 3,554 · see citing works
Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)
Norgren, L., Hiatt, W. R., Dormandy, J., Nehler, M. R., Harris, K. A., & Fowkes, F. G. R. (2006) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2006.09.024 · Cited by 2,846 · see citing works
Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care
Hirsch, A. T. (2001) · JAMA · doi:10.1001/jama.286.11.1317 · Cited by 2,835 · see citing works
The Continuing Epidemics of Obesity and Diabetes in the United States
Mokdad, A. H. (2001) · JAMA · doi:10.1001/jama.286.10.1195 · Cited by 2,730 · see citing works
DS14: Standard Assessment of Negative Affectivity, Social Inhibition, and Type D Personality
Denollet, J. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000149256.81953.49 · Cited by 1,556 · see citing works
Ouriel, K. M. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06351-6 · Cited by 868 · see citing works
Personality as independent predictor of long-term mortality in patients with coronary heart disease
Denollet, J., Rombouts, H., Gillebert, T. C., Brutsaert, D. L., Sys, S. U., Brutsaert, D. L., & Stroobant, N. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90007-0 · Cited by 679 · see citing works
Critical Issues in Peripheral Arterial Disease Detection and Management A Call to Action
Belch, J. J. F. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.8.884 · Cited by 551 · see citing works
Eyre, H., Kahn, R., Robertson, R. M., the ACS/ADA/AHA Collaborative Writing Committee, ACS/ADA/AHA Collaborative Writing Committee Members, Clark, N. G., Doyle, C., Hong, Y., Gansler, T., Glynn, T., et al. (2004) · Circulation · doi:10.1161/01.cir.0000133321.00456.00 · Cited by 542 · see citing works
Use of ankle brachial pressure index to predict cardiovascular events and death: a cohort study
Leng, G. C., Fowkes, F. G. R., Alexander, L. E. E., Dunbar, J., Housley, E., & Ruckley, C. V. (1996) · BMJ · doi:10.1136/bmj.313.7070.1440 · Cited by 525 · see citing works
Peripheral Arterial Disease: Morbidity and Mortality Implications
Golomb, B. A., Dang, T. T., & Criqui, M. H. (2006) · Circulation · doi:10.1161/circulationaha.105.593442 · Cited by 498 · see citing works
Backer, G. D., Ambrosioni, E., Broch-Johnsen, K., Brotons, C., Cífková, R., Dallongeville, J., Ebrahim, S. B. J., Færgeman, O., Graham, I. M., Mancia, G., et al. (2003) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/00149831-200308000-00004 · Cited by 440 · see citing works
Inadequate Response to Treatment in Coronary Heart Disease
Denollet, J., Vaes, J., & Brutsaert, D. L. (2000) · Circulation · doi:10.1161/01.cir.102.6.630 · Cited by 388 · see citing works
Impact of Cardiac Rehabilitation on Depression and Its Associated Mortality
Milani, R. V., & Lavie, C. J. (2007) · The American Journal of Medicine · doi:10.1016/j.amjmed.2007.03.026 · Cited by 347 · see citing works
Eyre, H. J., Kahn, R., Robertson, R. M., Clark, N. G., Doyle, C., Gansler, T. S., Glynn, T., Hong, Y., Smith, R. A., Taubert, K. A., et al. (2004) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.54.4.190 · Cited by 328 · see citing works
Personality and Mortality After Myocardial Infarction
Denollet, J., Sys, S. U., & Brutsaert, D. L. (1995) · Psychosomatic Medicine · doi:10.1097/00006842-199511000-00011 · Cited by 310 · see citing works
Type D personality, cardiac events, and impaired quality of life: a review
Pedersen, S. S., & Denollet, J. (2003) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/00149831-200308000-00005 · Cited by 283 · see citing works
Independent importance of psychosocial factors for prognosis after myocardial infarction
Welin, C., Lappas, G., & Wilhelmsen, L. (2000) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2000.00694.x · Cited by 277 · see citing works
Type D personality is related to cardiovascular and neuroendocrine reactivity to acute stress
Habra, M. E., Linden, W., Anderson, J. C., & Weinberg, J. (2003) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00553-6 · Cited by 245 · see citing works
Denollet, J., Pedersen, S. S., Vrints, C. J., & Conraads, V. M. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.10.035 · Cited by 236 · see citing works
Personality and coronary heart disease: The type-D scale-16 (DS16)
Denollet, J. (1998) · Annals of Behavioral Medicine · doi:10.1007/bf02884962 · Cited by 212 · see citing works
Cortisol awakening response is elevated in acute coronary syndrome patients with type-D personality
Whitehead, D. L., Perkins-Porras, L., Strike, P. C., Magid, K. S., & Steptoe, A. (2007) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2006.11.005 · Cited by 159 · see citing works
Occurrence of Secondary Ischemic Events Among Persons With Atherosclerotic Vascular Disease
Vickrey, B. G., Rector, T. S., Wickstrom, S. L., Guzy, P. M., Sloss, E. M., Gorelick, P. B., Garber, S., McCaffrey, D. F., Dake, M. D., & Levin, R. A. (2002) · Stroke · doi:10.1161/hs0402.105246 · Cited by 159 · see citing works
Failure to consult for symptoms of heart failure in patients with a type-D personality
Schiffer, A., Denollet, J., Widdershoven, J., Hendriks, E. H., & Smith, O. R. (2007) · Heart · doi:10.1136/hrt.2006.102822 · Cited by 149 · see citing works
Cytokines and immune activation in systolic heart failure: the role of Type D personality
Denollet, J., Conraads, V. M., Brutsaert, D. L., De Clerck, L. S., Stevens, W. J., & Vrints, C. J. (2003) · Brain, Behavior, and Immunity · doi:10.1016/s0889-1591(03)00060-6 · Cited by 140 · see citing works
Albus, C., Jordan, J., & Herrmann‐Lingen, C. (2004) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/01.hjr.0000116823.84388.6c · Cited by 125 · see citing works
Conraads, V. M., Denollet, J., De Clerck, L. S., Stevens, W. J., Bridts, C., & Vrints, C. J. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2005.10.013 · Cited by 119 · see citing works
Al‐Ruzzeh, S., Athanasiou, T., Mangoush, O., Wray, J., Modine, T., George, S., & Amrani, M. (2005) · Heart · doi:10.1136/hrt.2004.047068 · Cited by 102 · see citing works
Breek, J. C., Hamming, J. F., Vries, J. D., et al. (2002) · Journal of Vascular Surgery · doi:10.1067/mva.2002.124369 · Cited by 84 · see citing works
Vogt, M. T., Wolfson, S. K., & Kuller, L. H. (1993) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(93)90091-e · Cited by 69 · see citing works
Personality and Social Predictors of Atherosclerotic Progression: Edinburgh Artery Study
Whiteman, M. C., Deary, I. J., & Fowkes, F. G. R. (2000) · Psychosomatic Medicine · doi:10.1097/00006842-200009000-00015 · Cited by 67 · see citing works
Criqui, M. H. (2001) · The American Journal of Cardiology · doi:10.1016/s0002-9149(01)01881-1 · Cited by 65 · see citing works
Hostile personality and risks of peripheral arterial disease in the general population.
Deary, I. J., Fowkes, F. G. R., Donnan, P. T., & Housley, E. (1994) · Psychosomatic Medicine · doi:10.1097/00006842-199405000-00004 · Cited by 65 · see citing works
Psychological Distress as a Risk Factor for Stroke-Related Mortality
Carney, R. M., & Freedland, K. E. (2002) · Stroke · doi:10.1161/str.33.1.5 · Cited by 60 · see citing works
Wattanakit, K., Williams, J. E., Schreiner, P. J., Hirsch, A. T., & Folsom, A. R. (2005) · Vascular Medicine · doi:10.1191/1358863x05vm622oa · Cited by 60 · cited 2× · see citing works
“Scarce evidence exists that personality traits, such as hostility and anger, are associated with PAD and atherosclerotic progression as measured by the ABI.(10,11,17) Traditional risk factors, such as age, diabetes, and renal disease, were also independently associated with all-cause mortality; these findings are in l…”
ResultLange, S., Trampisch, H., Haberl, R., Darius, H., Pittrow, D., Schuster, A., von Stritzky, B., Tepohl, G., Allenberg, J., & Diehm, C. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.09.003 · Cited by 54 · see citing works
Aquarius, A. E. (2007) · Archives of Surgery · doi:10.1001/archsurg.142.7.662 · Cited by 49 · see citing works
Self-citationThe International Pandemic of Chronic Cardiovascular Disease
McDermott, M. M. (2007) · JAMA · doi:10.1001/jama.297.11.1253 · Cited by 49 · see citing works
Long Term Prognosis in Patients with Peripheral Arterial Disease Treated with Antiplatelet Agents
Fiotti, N., Altamura, N., Cappelli, C., et al. (2003) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/s1078-5884(03)00318-6 · Cited by 32 · see citing works
Milyo, J. D., & Mellor, J. M. (2003) · Health Services Research · doi:10.1111/j.1475-6773.2003.00202.x · Cited by 31 · see citing works
Aquarius, A. E., Denollet, J., Hamming, J. F., et al. (2005) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2004.12.041 · Cited by 30 · see citing works
Self-citationBerry, J. D., Lloyd‐Jones, D. M., Garside, D. B., et al. (2007) · Annals of Epidemiology · doi:10.1016/j.annepidem.2007.03.010 · Cited by 24 · see citing works
Wilson, A. M., Bachoo, P., MacKay, I. A., Cassar, K., & Brittenden, J. (2007) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2006.12.026 · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Denollet, J., Schiffer, A. A., & Spek, V. (2010) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.109.934406 · Cited by 282 · see citing works
Chapman, B. P., Roberts, B., & Duberstein, P. (2011) · Journal of Aging Research · doi:10.4061/2011/759170 · Cited by 283 · see citing works
“5 years in patients with chronic heart failure (CHF) [141], over 4 years in peripheral artery disease (PAD) patients who underwent vascular surgery [142], and over 6 years in coronary artery disease (CAD) patients [143].”
BackgroundStauber, S., Guéra, V., Barth, J., Schmid, J. P., Saner, H., Znoj, H., Grolimund, J., & von Känel, R. (2013) · Vascular Medicine · doi:10.1177/1358863x13505861 · Cited by 39 · see citing works
- Authors
- Aquarius, A. E.
- Affiliations
- Tilburg University (NL)
- Corresponding author
- Aquarius, Annelies E.
- Venue
- Archives of Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 2009-08-14
- Volume
- 144
- Issue
- 8
- Pages
- 728
- ISSN
- 0004-0010 (ISSN-L)
- OpenAlex
- W2086708235
- Cited by
- 43
- References
- 44
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 3 · 2012: 9
- FWCI
- 4.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vascular Procedures and Complications
- Keywords
- Type D personality, peripheral arterial disease, all-cause mortality, psychological characteristics, risk prediction, ankle-brachial index, diabetes mellitus, kidney disease, high-risk patient identification
- MeSH terms
- Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Personality, Pilot Projects, Prognosis, Quality of Life, Risk Factors, Comorbidity, Logistic Models, Peripheral Vascular Diseases, Ankle Brachial Index
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review