The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Hypotensive Agents and Pressor Substances: The Effect of Epinephrine, Norepinephrine, Angiotensin II, and Others on the Secretory Rate of Aldosterone in Man
Abstract
The effect of hypotensive agents and of pressor substances on the rate of secretion of aldosterone was determined in normal subjects and in patients with hypertension or edema. The medullary hormones were studied because, in excess, they can produce hypertension in man. Angiotensin was studied because the major pathology of malignant hypertension is renal. The present work indicates that induced changes in the arterial blood pressure do not necessarily affect aldosterone secretion. The medullary hormones modified aldosterone output in a variable way, depending in part on the state of sodium balance. In contrast to the catecholamines, angiotensin consistently produced an increased secretion of aldosterone. The results suggest that aldosterone may regulate salt balance and blood pressure by its interaction with pressor substances such as angiotensin.
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Citations
Cites
STUDIES ON EXPERIMENTAL HYPERTENSION
Goldblatt, H., Lynch, J., Hanzal, R. F., & Summerville, W. W. (1934) · Journal of Experimental Medicine · doi:10.1084/jem.59.3.347 · Cited by 2,142
THE EXISTENCE OF TWO FORMS OF HYPERTENSIN
Skeggs, L. T., Marsh, W. H., Kahn, J. R., & Shumway, N. P. (1954) · Journal of Experimental Medicine · doi:10.1084/jem.99.3.275 · Cited by 457
Page, I. H., & Helmer, O. M. (1940) · Journal of Experimental Medicine · doi:10.1084/jem.71.1.29 · Cited by 434
Interrelationship of Electrolytes, Juxtaglomerular Cells and Hypertension
Tobian, L. (1960) · Physiological Reviews · doi:10.1152/physrev.1960.40.2.280 · Cited by 378
The substance causing renal hypertension
Braun-Menendez, E., Fasciolo, J. C., Leloir, L. F., & Muñoz, J. M. (1940) · The Journal of Physiology · doi:10.1113/jphysiol.1940.sp003850 · Cited by 362
ALDOSTERONE SECRETION AND PRIMARY AND MALIGNANT HYPERTENSION *
Laragh, J. H., Ulick, S., Januszewicz, V., Deming, Q. B., Kelly, W. G., & Lieberman, S. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104124 · Cited by 305
Self-citationTHE HEMODYNAMIC EFFECTS OF ANGIOTONIN IN NORMAL MAN 1
Bradley, S. E., & Parker, B. (1941) · Journal of Clinical Investigation · doi:10.1172/jci101265 · Cited by 50
Aldosterone in fluid and electrolyte disorders: Hyper- and hypoaldosteronism
Laragh, J. H. (1960) · Journal of Chronic Diseases · doi:10.1016/0021-9681(60)90041-2 · Cited by 39
Self-citation
Cited by
Guyton, A. C., Coleman, T. G., Cowley, A. W., Scheel, K. W., Manning, R. D., & Norman, R. A. (1972) · The American Journal of Medicine · doi:10.1016/0002-9343(72)90050-2 · Cited by 1,050
Body Fluid Balance During Heat Stress in Humans
Mack, G. W., & Nadel, E. R. (1996) · Comprehensive Physiology · doi:10.1002/cphy.cp040110 · Cited by 103
Walker, W. G., Moore, M. A., Horvath, J. S., & Whelton, P. K. (1976) · Circulation Research · doi:10.1161/01.res.38.6.477 · Cited by 28
Metadata
- Authors
- Laragh, J. H.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1960-09-17
- Volume
- 174
- Issue
- 3
- Pages
- 234
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2090369272
- Cited by
- 522
- References
- 8
- FWCI
- 47.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Laragh, J. H. (1960). Hypotensive Agents and Pressor Substances: The Effect of Epinephrine, Norepinephrine, Angiotensin II, and Others on the Secretory Rate of Aldosterone in Man. JAMA. https://doi.org/10.1001/jama.1960.03030030014003
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
