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Association Between Nutritional Status and Cognitive Functioning in a Healthy Elderly Population
Abstract
We evaluated the association between nutritional status and cognitive functioning in 260 noninstitutionalized men and women older than 60 years who had no known physical illnesses and were receiving no medications. Nutritional status was evaluated by three-day food records and also by biochemical determination of blood levels of specific nutrients. Cognitive status was evaluated by the Halstead-Reitan Categories Test (a nonverbal test of abstract thinking ability) and by the Wechsler Memory Test. Subjects with low blood levels of vitamins C or B12 scored worse on both tests. Subjects with low levels of riboflavin or folic acid scored worse on the categories test. These differences remained significant after controlling for age, gender, level of income, and amount of education. "Subclinical" malnutrition may play a small role in the depression of cognitive function detectable in some elderly individuals, or depressed cognitive function may result in reduced nutrient intake.
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Cited by
Blount, B. C., Mack, M. M., Wehr, C. M., MacGregor, J. T., Hiatt, R. A., Wang, G., Wickramasinghe, S. N., Everson, R. B., & Ames, B. N. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3290 · Cited by 1,139
Vitamin B12, folic acid, and the nervous system
Reynolds, E. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70598-1 · Cited by 860
Improved discrimination of AD patients using β-amyloid (1-42) and tau levels in CSF
Hulstaert, F., Blennow, K., Ivanoiu, A., Schoonderwaldt, H. C., Riemenschneider, M., Deyn, P. P. D., Bancher, C., Cras, P., Wiltfang, J., Mehta, P. D., et al. (1999) · Neurology · doi:10.1212/wnl.52.8.1555 · Cited by 724
Cytokines and cognition–the case for a head-to-toe inflammatory paradigm.
Wilson, C. J., Finch, C. E., & Cohen, H. J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50619.x · Cited by 637
Caloric restriction improves memory in elderly humans
Witte, A. V., Fobker, M., Gellner, R., Knecht, S., & Flöel, A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808587106 · Cited by 574
Metadata
- Authors
- Goodwin, J. S.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1983-06-03
- Volume
- 249
- Issue
- 21
- Pages
- 2917
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2035563772
- Cited by
- 495
- References
- 0
- FWCI
- 6.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Goodwin, J. S. (1983). Association Between Nutritional Status and Cognitive Functioning in a Healthy Elderly Population. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1983.03330450047024
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
