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Heavy Smokers, Smoking Cessation, and Clonidine: Results of a Double-blind, Randomized Trial
Abstract
Seventy-one heavy smokers who had failed in previous attempts to stop smoking participated in a randomized clinical trial to test the efficacy of clonidine as an aid in smoking cessation. The success rate in clonidine-treated subjects (verified by serum cotinine concentration) was more than twice that in the placebo-treated subjects. When the data were stratified by gender, a strong effect present in women was not apparent in men. After six months, cessation rates remained significantly higher among smokers treated with clonidine than those receiving placebo. The data also revealed an unexpectedly high prevalence (61%) of a history of major depression in this sample and a significant negative effect of such a history on cessation regardless of treatment. These findings, highly suggestive of an important role of clonidine in smoking cessation, warrant further studies to establish the long-term (greater than or equal to 12 months) efficacy of this drug and to replicate the association between nicotine dependence and depression.
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“a majority of smokers enrolled in smoking cessation programs have a history of depressive episodes (Dalack, Glassman, Rivelli, Covey, & Stetner, 1995; Glassman et al., 1988; Lerman et al., 1996)”
From Nicotine addiction and psychiatric disorders (2015) · cites this paper as Glassman et al., 1988
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Items 301–400 of 410
Depression and Coronary Heart Disease
Khan, F., Kulaksızoğlu, B., & Çilingiroğlu, M. (2010) · Current Atherosclerosis Reports · doi:10.1007/s11883-010-0096-5 · Cited by 21
“if that person attempted to quit, it increased the chance that the person would fail [6].”
BackgroundAgosti, V., & LEVIN, F. R. (2008) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-008-0407-0 · Cited by 11
“Studies of clinical and epidemiological samples have noted that major depression and alcohol use disorders reduce the likelihood of quitting [2, 14, 36].”
Craving: A Problematic Concept in Smoking Research
Gilbert, H. M., & Warburton, D. M. (2000) · Addiction Research & Theory · doi:10.3109/16066350009009522 · Cited by 10
Terry, M. L., Berkowitz, H. D., Kerstein, M. D., & FACS (1998) · Surgical Clinics of North America · doi:10.1016/s0039-6109(05)70323-6 · Cited by 11
Smoking cessation: Part 2--Pharmacologic approaches.
Wongwiwatthananukit, S., Jack, H. M., & Popovich, N. G. (1998) · Journal of the American Pharmacists Association · doi:10.1016/s1086-5802(16)30330-8 · Cited by 11
Klesges, R. C., Benowitz, N. L., & Meyers, A. W. (1991) · Behavior Therapy · doi:10.1016/s0005-7894(05)80175-3 · Cited by 12
Who smokes? Why?: Psychiatric aspects of continued cigarette usage among lawyers in Washington State
Chiles, J. A., Benjamin, G. A. H., & Cahn, T. S. (1990) · Comprehensive Psychiatry · doi:10.1016/0010-440x(90)90022-k · Cited by 10
Estado actual y futuras terapias farmacológicas en la deshabituación tabáquica
Trullén, A. P., & Jiménez, M. L. C. (2001) · Archivos de Bronconeumología · doi:10.1016/s0300-2896(01)75048-x · Cited by 7
Depression Symptoms Among Homeless Smokers: Effect of Motivational Interviewing
Robinson, C. D., Rogers, C. R., & Okuyemi, K. S. (2016) · Substance Use & Misuse · doi:10.3109/10826084.2016.1170143 · Cited by 10
Levin, E. D., Wells, C., Johnson, J. E., Rezvani, A. H., Bymaster, F. P., & Rose, J. E. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.06.041 · Cited by 10
“The noradrenergic α2 agonist clonidine has been shown to improve smoking cessation pharmacotherapy (Glassman et al., 1988).”
BackgroundUpdates in the Smoking and Smoking Cessation of Korean Women
Suh, K.-H. (2007) · doi:10.17315/kjhp.2007.12.4.002 · Cited by 10
Genetic testing: the future of smoking cessation therapy?
Johnstone, E., York, E. E., & Walton, R. (2002) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.2.1.60 · Cited by 10
The additive effects of smoking and hypertension. More reasons to help your patients kick the habit.
Kochar, M., & Bindra, R. S. (1996) · Postgraduate medicine · doi:10.3810/pgm.1996.11.114 · Cited by 10
Smoking Habit and Psychological Distress in Adolescent Female Students
Schifano, F., Forza, G., & Gallimberti, L. (1994) · American Journal on Addictions · doi:10.1111/j.1521-0391.1994.tb00376.x · Cited by 9
Jayanthi, V., Probert, C., Sher, K., et al. (1991) · Respiratory Medicine · doi:10.1016/s0954-6111(06)80076-4 · Cited by 10
Release of contractile agents from rat vas deferens by clonidine.
Jurkiewicz, N. H., & Jurkiewicz, A. (1991) · Life Science · doi:10.1016/0024-3205(91)90059-k · Cited by 10
Sharma, S., Archie, S. R., Kanchanwala, V., Mimun, K., Rahman, M. A., Zhang, Y., & Abbruscato, T. J. (2022) · Frontiers in Drug Delivery · doi:10.3389/fddev.2022.886099 · Cited by 18
Bourdeau, B. L., Brady, M. K., & Cronin, J. J. (2006) · Journal of Nonprofit & Public Sector Marketing · doi:10.1300/j054v16n01_07 · Cited by 9
“…Newcomb, and Bentler 1996), the correlation between cigarette smoking and depression has been identified in several populations, including psychiatric outpatients (Hughes et al. 1986), heavy smokers (Glassman et al. 1988), and random population surveys (Anda et al. 1990; Glassman et al. 1990).”
BackgroundHitsman, B. L., Spring, B. J., Borrelli, B., McChargue, D. E., & NIAURA, R. S. (2004) · Nicotine & Tobacco Research · doi:10.1080/14622200410001727911 · Cited by 9
“(2003) are as follows: placebo clonidinezintensive behavioral treatment (Glassman et al., 1988; Covey et al., 1993; Glassman et al., 1993), psychoeducationznicotine gum (Hall, Muñoz, & Reus, 1994), relapse preventionzaversive smoking (Ginsberg et al.”
BackgroundPsychosocial Therapies for Tobacco Dependence in Mental Health and Other Substance Use Populations
Steinberg, M. L., Hall, S. M., & Rustin, T. A. (2003) · Psychiatric Annals · doi:10.3928/0048-5713-20030701-08 · Cited by 7
Dépressions sévères et addictions
Cottencin, O. (2009) · L Encéphale · doi:10.1016/s0013-7006(09)73483-9 · Cited by 11
McDermut, W., Haaga, D., & Shayne, V. T. (1991) · doi:10.1016/s0005-7894(05)80375-2 · Cited by 8
A survey of physicians' smoking counseling practices.
Jelley, M., & Prochazka, A. (1991) · American Journal of the Medical Sciences · doi:10.1097/00000441-199104000-00004 · Cited by 8
Lauro, I. S., Lores, L. M. V., Coll, F., Carreras, J. M., & Quesada, M. (2002) · Archivos de Bronconeumología · doi:10.1016/s0300-2896(02)75238-1 · Cited by 11
Cigarette Smoking and Its Comorbidity
Glassman, A. H. (1997) · PsycEXTRA Dataset · doi:10.1037/e495582006-004 · Cited by 8
“In addition to the available epidemiological data, the association between depression and both smoking and smoking cessation has also been replicated in several smoking cessation clinics (Glassman et al. 1988, 1993; Hall et al. 1992; Kinnunen et al. 1994).”
BackgroundSelf-citationThe effectiveness of smoking cessation programs: Determinants and outcomes
BRETELER, M. H. M., Schotborg, E. J., & Schippers, G. M. (1996) · Psychology and Health · doi:10.1080/08870449608401979 · Cited by 8
Smoking cessation strategies: what works, what doesn't.
Sachs, D. P. L. (1990) · The Journal of the American Dental Association (1939) · doi:10.14219/jada.archive.1990.0283 · Cited by 8
McCracken, J. T., & Martin, W. (1997) · Journal of the American Academy of Child and Adolescent Psychiatry · doi:10.1097/00004583-199702000-00002 · Cited by 7
Chronic obstructive pulmonary disease--can we do better?
Petty, T. L. (1990) · Chest · doi:10.1378/chest.97.2.2s · Cited by 7
Treatment of nicotine dependence.
Fagerström, K. (1989) · Progress in Brain Research · doi:10.1016/s0079-6123(08)62491-7 · Cited by 7
Current smoking rate in patients with psychiatric disorders in Japan: Questionnaire survey
Umene‐Nakano, W., Yoshimura, R., Hoshuyama, T., Yoshii, C., Hayashi, K., Nakano, H., Hori, H., Ikenouchi, A., Katsuki, A., Atake, K., et al. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.03.024 · Cited by 5
Cohn, A. M., Strong, D. R., Abrantes, A. M., & Brown, R. A. (2010) · Addictive Disorders & Their Treatment · doi:10.1097/adt.0b013e3181b91c6b · Cited by 5
Screening for erectile dysfunction: rationale
Goldstein, I. (2000) · International journal of impotence research · doi:10.1038/sj.ijir.3900595 · Cited by 6
Use of Sustained-Release Bupropion in Specific Patient Populations for Smoking Cessation
Tonstad, S. (2002) · Drugs · doi:10.2165/00003495-200262002-00004 · Cited by 27
“[16] Depressive symptoms can hamper attempts to quit smoking,[17] and a history of depression[18] or alcoholism[19,20] has been associated with poor outcomes for smoking treatment.”
BackgroundEine Untersuchung der Zusammenhänge zwischen koronarer Herzkrankheit und Depression
Glassman, A., & Giardina, E. (1999) · doi:10.1007/978-3-642-60175-0_14 · Cited by 6
Self-citationSternberg, Z. (2015) · NeuroMolecular Medicine · doi:10.1007/s12017-015-8375-5 · Cited by 4
“explain the close association between heavy smoking habit and depression (Glassman et al. 1988).”
BackgroundInfluentialA Brief Review of Pharmacotherapies for Smoking Cessation
Lam, C. Y., Minnix, J. A., Robinson, J. D., & Cinciripini, P. M. (2006) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2006.0047 · Cited by 4
“Data from clinical trials indicated that a large number of patients taking clonidine reported side effects (median 71%) and that approximately 14% of patients discontinued the drug because of side effects.(54) Common side effects include fatigue, sedation, dry mouth, dizziness, and postural hypotension.”
BackgroundSex differences in the relation of mood to weight gain after quitting smoking.
Frederick, S. L., Hall, S. M., Humfleet, G. L., & Muñoz, R. F. (1996) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.4.2.178 · Cited by 5
Smoking cessation: the side effects of clonidine.
Tønnesen, P. (1989) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.1989.03420220054009 · Cited by 5
Improving the diagnosis and treatment of nicotine dependence.
Henningfield, J. E. (1988) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.1988.03410110121041 · Cited by 5
Clonidine and Related Imidazoline Derivatives
Wiley, J. F. (2007) · Elsevier eBooks · doi:10.1016/b978-0-7216-0693-4.50067-0 · Cited by 4
Koob, G. F., & Moal, M. L. (2006) · Elsevier eBooks · doi:10.1016/b978-012419239-3/50043-6 · Cited by 10
Psychological interventions: State of the art
Hall, S. (1999) · Nicotine & Tobacco Research · doi:10.1080/14622299050012021 · Cited by 4
Management of the Hypertensive Patient Who Smokes
Pardell, H., Tresserras, R., Saltó, E., Armario, P., & ndez, R. H. (1998) · Drugs · doi:10.2165/00003495-199856020-00002 · Cited by 12
“[82]”
Achieving Smoking Cessation in Nicotine-Dependent Individuals
Mielke, M. M., Jorenby, D. E., & Fiore, M. C. (1997) · CNS Drugs · doi:10.2165/00023210-199708010-00002 · Cited by 4
How to help your patients quit smoking.
Wong, J. (1993) · Postgraduate medicine · doi:10.1080/00325481.1993.11945688 · Cited by 4
Smoking behaviour before and after attendance at a health promotion clinic in general practice
Sacks, G., Anderson, F., LAWLESS, M., & Thorogood, M. (1992) · Health Education Journal · doi:10.1177/001789699205100103 · Cited by 3
Scott, G. C., Chu, C.-S., & Braun, S. (1991) · Chest · doi:10.1378/chest.100.4.1035 · Cited by 4
An unusual cause of clonidine toxicity.
Klein, M. D. (1991) · American Journal of Emergency Medicine · doi:10.1016/0735-6757(91)90074-t · Cited by 4
Nicotine Dependence: Diagnosis, Chemistry and Pharmacological Treatments
Miller, N. S., Cocores, J., & Belkin, B. (1991) · doi:10.3109/10401239109147967 · Cited by 4
Nicotine-replacement therapy in cessation of smoking.
Peters, J. A. (1990) · Mayo Clinic proceedings · doi:10.1016/s0025-6196(12)62196-x · Cited by 4
Future Trends in the Pharmacological Treatment of Smoking Cessation
Glassman, A. H., & Covey, L. S. (1990) · Drugs · doi:10.2165/00003495-199040010-00001 · Cited by 18
Self-citationCommon Substrates of Dysphoria in Stimulant Drug Abuse and Primary Depression: Therapeutic Targets
Baicy, K., Bearden, C. E., Monterosso, J. R., Brody, A. L., Isaacson, A. J., & London, E. D. (2005) · International review of neurobiology · doi:10.1016/s0074-7742(04)65005-7 · Cited by 4
Psychopharmacology of smoking cessation medications: focus on patients with mental health disorders
Castaldelli-Maia, J. M., de Oliveira, V. C., Irber, F. M., Blaas, I. K., Angerville, B., Martins-da-Silva, A. S., Gimenes, G. K., Campos, M. W., Torales, J. C., Ventriglio, A., et al. (2023) · International Review of Psychiatry · doi:10.1080/09540261.2023.2249084 · Cited by 3
“…posterior hypothalamus and spinal cord, which can cause sedation and a decrease in blood pressure and heart rate (Barboza et al., 2016; Bruijnzeel et al., 2010; Elrashidi & Ebbert, 2014; Glassman et al., 1988; Gowing et al., 2014; Siu & Tyndale, 2007; Toce et al., 2018; Yasaei & Saadabadi, 2021).”
BackgroundVerplaetse, T. L., & McKee, S. A. (2016) · Current Addiction Reports · doi:10.1007/s40429-016-0115-x · Cited by 5
A Short-Term Effectiveness of Smoking Cessation Intervention in Outpatient Department of Pulmonology
Yeo, C. D., Kang, H. H., Kang, J. Y., Kim, S. K., Kim, M. S., Kim, S. S., Lee, S. H., & Moon, H. S. (2011) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2011.71.2.114 · Cited by 3
Nicotine addiction and its Pharmacological effects: A Review
Kumar, S., Nain, P., & Singh, J. (2011) · doi:10.7324/japs.2011.103.33 · Cited by 3
Tobacco smoking in patients with cardiovascular disease
Joseph, A. M., & An, L. C. (2001) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-001-0093-7 · Cited by 4
“There are several clinical trials showing a benefit for smoking cessation, especially in women [ 25 ].”
BackgroundFrontiers in Pharmacologic Treatment of Alcohol, Cocaine, and Nicotine Dependence
Vaughan, D. A. (1990) · Psychiatric Annals · doi:10.3928/0048-5713-19901201-05 · Cited by 4
Belt, W. (1990) · doi:10.1055/s-2007-1006192 · Cited by 3
“Clonidine, a long proved antihypertensive drug, has recently been shown to increase smoking cessation success rates and has been released in a convenient transdermal delivery system.(90,91) In any hypertensive patient, the goal remains to get the pressure down.”
BackgroundAn Examination of the Linkage Between Ischemic Heart Disease and Depression
Glassman, A., & Giardina, E. (2001) · doi:10.1007/978-3-642-59519-6_79 · Cited by 3
Self-citationNicotine-Dependent Psychiatric Patients
Taylor, W. A., Cocores, J. A., & Gold, M. S. (1991) · Springer eBooks · doi:10.1007/978-1-4613-9112-8_24 · Cited by 4
Legal concept of torts and emotional distress.
Tobak, M. (1989) · American Journal of Psychiatry · doi:10.1176/ajp.146.9.aj14691237 · Cited by 2
Tomassoni, A. J. (2016) · Springer eBooks · doi:10.1007/978-3-319-20790-2_27-1 · Cited by 2
Heart Disease and Cognitive/Neuropsychiatric Disorders
Tulner, D. M., & den Boer, H. A. (2000) · Humana Press eBooks · doi:10.1007/978-1-59259-713-0_13 · Cited by 2
Pharmacotherapy of Addiction: Introduction and Principles
Levin, F., & Kleber, H. (1996) · doi:10.1007/978-3-642-60963-3_12 · Cited by 2
Gender Differences in Smoking Cessation: Where? When? Who? Why?
Gritz, E., Brooks, L., & Nielsen, I. (1995) · doi:10.1007/978-1-4615-1907-2_85 · Cited by 2
Tabac et psychotropes: incidences pharmacologiques et pharmacocliniques
Joober, R., Attar-Lévy, D., Amado-Boccara, I., et al. (1995) · EMC - Psychiatrie · doi:10.1016/s0246-1072(19)30338-4 · Cited by 2
Strategien zur Verminderung des Nikotinabusus bei Patienten mit kardiovaskulären Erkrankungen
Gohlke, H. (1992) · Steinkopff eBooks · doi:10.1007/978-3-642-93676-0_5 · Cited by 2
Nicotinic Cholinergic Signaling in the Human Brain – Systems Perspective
Mobascher, A., & Winterer, G. (2010) · Wiley eBooks · doi:10.1002/9783527630271.ch8 · Cited by 1
Mechanismen der Nikotinabhängigkeit
Mobascher, A., & Winterer, G. (2008) · doi:10.1055/s-2008-1038159 · Cited by 1
Blanchardière, A. D. L., Depieds, D., & Gueyffier, F. (2006) · La Presse Médicale · doi:10.1016/s0755-4982(06)74833-3 · Cited by 1
Successfully Treating Nicotine Dependence
Glover, E. (2006) · doi:10.1080/19325037.2006.10598872 · Cited by 1
Mood disorders in patients with COPD: overview of current research and future needs
Clary, G. L. (2003) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.3.2.203 · Cited by 1
The interaction of depression and smoking on workplace productivity
Halpern, M. T., Khan, Z. M., & Rentz, A. M. (2004) · Research in human capital and development · doi:10.1016/s0194-3960(01)14015-1 · Cited by 1
Clonidine poisoning: Is there any effective therapy?
Wiley, J. (2000) · doi:10.1016/s1522-8401(00)90030-2 · Cited by 1
Kallgren, M. (1995) · doi:10.1016/s0950-3501(95)80055-7 · Cited by 1
Phenelzine produces subsensitivity to nicotine.
Dilsaver, S., Hariharan, M., & Davidson, R. (1993) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/0278-5846(93)90065-z · Cited by 1
Clinton, J. J. (1993) · Ophthalmology · doi:10.1016/s0161-6420(13)31983-6 · Cited by 1
Helping your patients who smoke quit for good. A quick and easy approach.
Kraner, S. E., & Graham, K. E. (1991) · Postgraduate medicine · doi:10.1080/00325481.1991.11700995 · Cited by 1
Prevention of emphysema. Importance of early identification.
Petty, T. L. (1989) · Postgraduate medicine · doi:10.1080/00325481.1989.11704477 · Cited by 1
The Relationship Between Mood, Stress, and Tobacco Smoking
Walderhaug, E., Cosgrove, K., Bhagwagar, Z., & Neumeister, A. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6373-4_10 · Cited by 1
Khaled, S. M. (2011) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/12876 · Cited by 1
DeBon, M. W., & Klesges, R. C. (1995) · Plenum series in rehabilitation and health · doi:10.1007/978-1-4899-1028-8_7 · Cited by 3
Psychosocial Factors and Nicotine Dependence
Kane, G. P. (1991) · Springer eBooks · doi:10.1007/978-1-4613-9112-8_2 · Cited by 3
Depression and the Dynamics of Smoking: A National Perspective
Anda, R. F. (1990) · JAMA · doi:10.1001/jama.1990.03450120053028 · Cited by 28
Bagul, V. A., & Ambadekar, S. R. (2026) · Discover Industrial Chemistry and Materials · doi:10.1007/s44508-026-00019-6
“A key randomized, double-blind, placebo-controlled study by Glassman et al. (1988) examined the potential of clonidine as an aid to smoking cessation [54].”
Effects of Depressive Disorder on Consumption of Tobacco in Brazil
Soares, L. D. S. A., & Teixeira, E. C. (2025) · Revista Facultad de Ciencias Económicas · doi:10.18359/rfce.6719
Ahmed, M. (2019) · Infections in Pregnancy · doi:10.1017/9781108684729.143
The neurobiology and treatment of tobacco dependence
Nguyen, T. A., & Anthenelli, R. M. (2008) · Current Cardiovascular Risk Reports · doi:10.1007/s12170-008-0076-2
“In one study, it doubled the rates of smoking cessation as compared with placebo in heavy smokers [ 35 ].”
ResultPharmacologic Treatments for Smoking Cessation
Jimenez-Ruiz, C. A., Fagerström, K. O., & Miranda, J. A. R. (2008) · Clinical Pulmonary Medicine · doi:10.1097/cpm.0b013e3181672252
“The treatment effect continued at the 6-month follow up.(49) The most common side effects with clonidine are dizziness, drowsiness, tiredness, weakness, and dry mouth.”
BackgroundKamholz, B. W., Gulliver, S. B., & Morissette, S. B. (2006) · Journal of Dual Diagnosis · doi:10.1300/j374v02n04_03
“More specific data indicate that smokers with current MDD (or a lifetime history of MDD) may be twice as likely to fail in their efforts to quit smoking (Breslau et al. 1992, 464-9; Glassman et al. 1988, 2863-6; Glassman et al. 1990, 1546-9; Hall et al. 1991, 312-3).”
BackgroundKrejci, J. A., Steinberg, M. L., Violette, N. M., & Ziedonis, D. M. (2006) · Journal of Dual Diagnosis · doi:10.1300/j374v02n04_02
“Several studies have demonstrated a clear association between smoking and depression (e.g., Breslau, Kilby, & Andreski, 1991; Glassman et al., 1988; Kendler et al., 1993).”
BackgroundPharmacological adjuncts for the treatment of withdrawal syndromes.
Sees, K. (1991) · Journal of Psychoactive Drugs · doi:10.1080/02791072.1991.10471609
Comment: Oral Clonidine in Nicotine Withdrawal
Day, R. G. (1989) · DICP : the annals of pharmacotherapy · doi:10.1177/106002808902301224
The Nurse Practitioners’ Role in Smoking Cessation
Christman, C., & Blngham, M. (1989) · Journal of the American Academy of Nurse Practitioners · doi:10.1111/j.1745-7599.1989.tb00739.x
Therapeutische Strategien bei Alkohol- und Tabakabhängigkeit
Lesch, O., Walter, H., Pombo›, S., HESSELBROCK, V. M., & Hesselbrock, M. N. (2020) · Springer eBooks · doi:10.1007/978-3-662-60284-3_9
Therapeutic Strategies in Alcohol and Tobacco Addiction
Lesch, O., Walter, H., Wetschka, C., et al. (2020) · Alcohol and Tobacco · doi:10.1007/978-3-7091-0146-9_9
Green, J. P., & Lynn, S. J. (2018) · Wiley eBooks · doi:10.1002/9781119139676.refs
Contribution of Translational Genetic Research to Our Understanding of Nicotine Dependence
Hall, F. S., Arime, Y., Saber, Y., & Sora, I. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802574-1.00007-7
Metadata
- Authors
- Glassman, A. H.
- Corresponding author
- Glassman, Alexander H.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1988-05-20
- Volume
- 259
- Issue
- 19
- Pages
- 2863
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W7214164996
- Cited by
- 0
- References
- 0
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- heavy smoking, smoking cessation, clonidine, nicotine dependence, tobacco use
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