The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Screening and Brief Intervention for Drug Use in Primary Care: The ASPIRE Randomized Clinical Trial
Open accessAbstract
IMPORTANCE: The United States has invested substantially in screening and brief intervention for illicit drug use and prescription drug misuse, based in part on evidence of efficacy for unhealthy alcohol use. However, it is not a recommended universal preventive service in primary care because of lack of evidence of efficacy. OBJECTIVE: To test the efficacy of 2 brief counseling interventions for unhealthy drug use (any illicit drug use or prescription drug misuse)-a brief negotiated interview (BNI) and an adaptation of motivational interviewing (MOTIV)-compared with no brief intervention. DESIGN, SETTING, AND PARTICIPANTS: This 3-group randomized trial took place at an urban hospital-based primary care internal medicine practice; 528 adult primary care patients with drug use (Alcohol, Smoking, and Substance Involvement Screening Test [ASSIST] substance-specific scores of ≥4) were identified by screening between June 2009 and January 2012 in Boston, Massachusetts. INTERVENTIONS: Two interventions were tested: the BNI is a 10- to 15-minute structured interview conducted by health educators; the MOTIV is a 30- to 45-minute intervention based on motivational interviewing with a 20- to 30-minute booster conducted by master's-level counselors. All study participants received a written list of substance use disorder treatment and mutual help resources. MAIN OUTCOMES AND MEASURES: Primary outcome was number of days of use in the past 30 days of the self-identified main drug as determined by a validated calendar method at 6 months. Secondary outcomes included other self-reported measures of drug use, drug use according to hair testing, ASSIST scores (severity), drug use consequences, unsafe sex, mutual help meeting attendance, and health care utilization. RESULTS: At baseline, 63% of participants reported their main drug was marijuana, 19% cocaine, and 17% opioids. At 6 months, 98% completed follow-up. Mean adjusted number of days using the main drug at 6 months was 12 for no brief intervention vs 11 for the BNI group (incidence rate ratio [IRR], 0.97; 95% CI, 0.77-1.22) and 12 for the MOTIV group (IRR, 1.05; 95% CI, 0.84-1.32; P = .81 for both comparisons vs no brief intervention). There were also no significant effects of BNI or MOTIV on any other outcome or in analyses stratified by main drug or drug use severity. CONCLUSIONS AND RELEVANCE: Brief intervention did not have efficacy for decreasing unhealthy drug use in primary care patients identified by screening. These results do not support widespread implementation of illicit drug use and prescription drug misuse screening and brief intervention. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00876941.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The positive findings from this earlier body of research, however, have not been supported by two recent large randomized trials that found no significant effect on illicit drug use in primary healthcare settings (Roy-Byrne et al., 2014; Saitz et al., 2014).”
From A randomized study of the use of screening, brief intervention, and referral to treatment (SBIRT) for drug and alcohol use with jail inmates (2017) · cites this paper as Saitz et al., 2014
In the citing paper
“The results of this study lend support to those studies that have found SBIRT to have no significant impact on drug use in medical settings (Roy-Byrne et al., 2014; Saitz et al., 2014) or on alcohol among probationers (Newbury-Birch et al., 2014; Stein et al., 2010).”
From A randomized study of the use of screening, brief intervention, and referral to treatment (SBIRT) for drug and alcohol use with jail inmates (2017) · cites this paper as Saitz et al., 2014
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
EuroQol: a new facility for the measurement of health-related quality of life
(1990) · Health Policy · doi:10.1016/0168-8510(90)90421-9 · Cited by 15,736
Motivational interviewing: preparing people for change.
Miller, W. R., & Rollnick, S. (2002) · Cited by 7,002
A sharper Bonferroni procedure for multiple tests of significance
HOCHBERG, Y. (1988) · Biometrika · doi:10.1093/biomet/75.4.800 · Cited by 4,829
The world health organization composite international diagnostic interview short-form (CIDI-SF)
Kessler, R. C., Andrews, G., Mroczek, D., Ustun, B., & Wittchen, H. (1998) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.47 · Cited by 2,242
Validation of the alcohol smoking and substance involvement screening test (ASSIST)
Humeniuk, R., Ali, R., Babor, T. F., Farrell, M., Formigoni, M. L., Jittiwutikarn, J., De Lacerda, R. B., Ling, W., Marsden, J., Monteiro, M., et al. (2008) · Addiction · doi:10.1111/j.1360-0443.2007.02114.x · Cited by 1,144
Moyer, A., Finney, J. W., Swearingen, C. E., & Vergun, P. (2002) · Addiction · doi:10.1046/j.1360-0443.2002.00018.x · Cited by 1,092
Kamb, M. L., Fishbein, M., Douglas, Jr., Rhodes, F., Rogers, J., Bolan, G., Zenilman, J., Hoxworth, T., Malotte, C. K., Iatesta, M., et al. (1998) · JAMA · doi:10.1001/jama.280.13.1161 · Cited by 973
Development and validation of an Overall Anxiety Severity and Impairment Scale (OASIS)
Norman, S. B., Hami Cissell, S., Means-Christensen, A. J., & Stein, M. B. (2006) · Depression and Anxiety · doi:10.1002/da.20182 · Cited by 770
Assessing competence in the use of motivational interviewing
Moyers, T. B., Martin, T., Manuel, J. K., Hendrickson, S. M. L., & Miller, W. R. (2005) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2004.11.001 · Cited by 738
Research works printed but not linked: 2
- [31]Hao L Naiman DQ Quantile Regression 2007 Sage Publications Thousand Oaks, CA
- [32]Koenker R Quantile Regression 2005 Cambridge University Press New York, NY
Cited by
Sorted by citations
Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence
D’Onofrio, G., O’Connor, P. G., Pantalon, M. V., Chawarski, M. C., Busch, S. H., Owens, P. H., Bernstein, S. L., & Fiellin, D. A. (2015) · JAMA · doi:10.1001/jama.2015.3474 · Cited by 913
McNeely, J., Wu, L.-T., Subramaniam, G., Sharma, G., Cathers, L. A., Svikis, D., Sleiter, L., Russell, L., Nordeck, C., Sharma, A., et al. (2016) · Annals of Internal Medicine · doi:10.7326/m16-0317 · Cited by 320
McNeely, J., Kumar, P. C., Rieckmann, T., Sedlander, E., Farkas, S., Chollak, C., Kannry, J. L., Vega, A., Waite, E. A., Peccoralo, L. A., et al. (2018) · Addiction Science & Clinical Practice · doi:10.1186/s13722-018-0110-8 · Cited by 303
Responding to global stimulant use: challenges and opportunities
Farrell, M., Martin, N. K., Stockings, E., Bórquez, A., Cepeda, J. A., Degenhardt, L., Ali, R., Tran, L. T., Rehm, J., Torrens, M., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(19)32230-5 · Cited by 310
DiClemente, C. C., Corno, C. M., Graydon, M. M., Wiprovnick, A. E., & Knoblach, D. J. (2017) · Psychology of Addictive Behaviors · doi:10.1037/adb0000318 · Cited by 294
Metadata
- Authors
- Saitz, R., Palfai, T. P. A., Cheng, D. M., Alford, D. P., Bernstein, J. A., Lloyd-Travaglini, C. A., Meli, S. M., Chaisson, C. E., & Samet, J. H.
- Affiliations
- Boston University (US)
- Corresponding author
- Saitz, Richard
- ORCID
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2014-08-06
- Volume
- 312
- Issue
- 5
- Pages
- 502
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC4667772
- OpenAlex
- W2083318583
- Cited by
- 280
- References
- 39
- Citations by year
- 2026: 4 · 2025: 11 · 2024: 4 · 2023: 9 · 2022: 10 · 2021: 17 · 2020: 18 · 2019: 42 · 2018: 28 · 2017: 48 · 2016: 37 · 2015: 46 · 2014: 6
- FWCI
- 34.60
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (R01DA025068)
- National Center for Research Resources (M01RR000533, UL1RR025771)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- screening and brief intervention, illicit drug use, prescription drug misuse, motivational interviewing, primary care, substance use disorders, cannabis use, cocaine use, opioid use, ASSIST screening, hair analysis, self-help groups, health care utilization, substance use consequences, unprotected sex, health educators, counselors, calendar method, harm reduction, internal medicine practice, urban primary care
- MeSH terms
- Adult, Female, Health Services, Hospitals, Urban, Humans, Male, Mass Screening, Middle Aged, Primary Health Care, Treatment Outcome, Substance-Related Disorders, Unsafe Sex, Self Report, Motivational Interviewing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
