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Association of Coffee and Caffeine Intake With the Risk of Parkinson Disease
Abstract
CONTEXT: The projected expansion in the next several decades of the elderly population at highest risk for Parkinson disease (PD) makes identification of factors that promote or prevent the disease an important goal. OBJECTIVE: To explore the association of coffee and dietary caffeine intake with risk of PD. DESIGN, SETTING, AND PARTICIPANTS: Data were analyzed from 30 years of follow-up of 8004 Japanese-American men (aged 45-68 years) enrolled in the prospective longitudinal Honolulu Heart Program between 1965 and 1968. MAIN OUTCOME MEASURE: Incident PD, by amount of coffee intake (measured at study enrollment and 6-year follow-up) and by total dietary caffeine intake (measured at enrollment). RESULTS: During follow-up, 102 men were identified as having PD. Age-adjusted incidence of PD declined consistently with increased amounts of coffee intake, from 10.4 per 10,000 person-years in men who drank no coffee to 1.9 per 10,000 person-years in men who drank at least 28 oz/d (P<.001 for trend). Similar relationships were observed with total caffeine intake (P<.001 for trend) and caffeine from non-coffee sources (P=.03 for trend). Consumption of increasing amounts of coffee was also associated with lower risk of PD in men who were never, past, and current smokers at baseline (P=.049, P=.22, and P=.02, respectively, for trend). Other nutrients in coffee, including niacin, were unrelated to PD incidence. The relationship between caffeine and PD was unaltered by intake of milk and sugar. CONCLUSIONS: Our findings indicate that higher coffee and caffeine intake is associated with a significantly lower incidence of PD. This effect appears to be independent of smoking. The data suggest that the mechanism is related to caffeine intake and not to other nutrients contained in coffee. JAMA. 2000;283:2674-2679.
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In the citing paper
“For women, there is a U-shaped relationship between coffee consumption and Parkinson’s disease risk, with women drinking 1–3 cups of coffee per day having the lowest risk.”
From Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human (2020) · cites this paper as [110]
In the citing paper
“An inverse association between coffee consumption and PD risk has been found in several epidemiological studies [110,121,122,123].”
From Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human (2020) · cites this paper as [110]
In the citing paper
“A study by Ascherio et al. reported that men who consumed a moderate amount of coffee had a significantly lower risk of PD than men who did not drink coffee at all [110].”
From Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human (2020) · cites this paper as [110]
Citations
Cites
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
Lang, A. E., & Lozano, A. M. (1998) · New England Journal of Medicine · doi:10.1056/nejm199810083391506 · Cited by 2,072
Nehlig, A., Daval, J., & Debry, G. (1992) · Brain Research Reviews · doi:10.1016/0165-0173(92)90012-b · Cited by 1,463
Tanner, C. M., Ottman, R., Goldman, S. M., Ellenberg, J., Chan, P., Mayeux, R. P., & Langston, J. W. (1999) · JAMA · doi:10.1001/jama.281.4.341 · Cited by 876
Epidemiology of parkinson’s disease
Tanner, C. M., & Goldman, S. M. (1996) · Neurologic Clinics · doi:10.1016/s0733-8619(05)70259-0 · Cited by 640
Coffee, Alcohol and Risk of Coronary Heart Disease among Japanese Men Living in Hawaii
Yano, K., Rhoads, G. G., & Kagan, A. (1977) · New England Journal of Medicine · doi:10.1056/nejm197708252970801 · Cited by 524
Prevalence of Dementia in Older Japanese-American Men in Hawaii: The Honolulu-Asia Aging Study
White, L. (1996) · JAMA · doi:10.1001/jama.1996.03540120033030 · Cited by 437
TEN-YEAR INCIDENCE OF CORONARY HEART DISEASE IN THE HONOLULU HEART PROGRAM
Yano, K., REED, D. M., & McGee, D. (1984) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113787 · Cited by 370
Worldwide Occurrence of Parkinson's Disease: An Updated Review
Zhang, Z., & Román, G. C. (1993) · Neuroepidemiology · doi:10.1159/000110318 · Cited by 332
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Bate, C., & Williams, A. (2015) · Biology · doi:10.3390/biology4030591 · Cited by 22
Development and application of nano-flavor-drug carriers in neurodegenerative diseases
Ji, W., Xiao, Z.-B., Liu, G., & Zhang, X. (2017) · Chinese Chemical Letters · doi:10.1016/j.cclet.2017.06.024 · Cited by 22
Nutrition and the risk for Parkinson’s disease: review of the literature
Gaenslen, A., Gasser, T., & Berg, D. (2008) · Journal of Neural Transmission · doi:10.1007/s00702-007-0005-4 · Cited by 23
Reich, M. S., Dietrich, M. S., Finlayson, A. J. R., Fischer, E. F., & Martin, P. R. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00751.x · Cited by 23
Li, F., Hatano, T., & Hattori, N. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104764 · Cited by 21
Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases
Xiang, Y., Naik, S. G., Zhao, L., Shi, J., & Ke, H. (2024) · Medicinal Research Reviews · doi:10.1002/med.22017 · Cited by 21
Sonu, V. K., Singh, I. R., Bhattacharjee, K., Joshi, S. R., & Mitra, S. (2018) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2018.1426497 · Cited by 21
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Abbott, R. D., Ross, G. W., Duda, J. E., Shin, C., Uyehara‐Lock, J. H., Masaki, K., Launer, L. J., White, L. R., Tanner, C. M., & Petrovitch, H. (2019) · Neurology · doi:10.1212/wnl.0000000000008241 · Cited by 22
Self-citationHistory of Parkinson's disease
Goldman, J. G., & Goetz, C. G. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)83005-3 · Cited by 21
Differences in Parkinson’s Disease Risk with Caffeine Intake and Postmenopausal Hormone Use
Kim, I. Y., O’Reilly, É. J., Hughes, K. C., Gao, X., Schwarzschild, M. A., & Ascherio, A. (2017) · Journal of Parkinson s Disease · doi:10.3233/jpd-171175 · Cited by 21
Parkinson's Disease: Genetics and Pathogenesis
Testa, C. M. (2007) · Wiley eBooks · doi:10.1002/9780470101001.hcn063 · Cited by 21
Glutathione-Mediated Neuroprotective Effect of Purine Derivatives
Matsumura, N., & Aoyama, K. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713067 · Cited by 21
Differential effects of age on human striatal adenosine A1and A2Areceptors
Mishina, M., Kimura, Y., Naganawa, M., Ishii, K., Oda, K., Sakata, M., Toyohara, J., Kobayashi, S., Katayama, Y., & Ishiwata, K. (2012) · Synapse · doi:10.1002/syn.21573 · Cited by 20
Tapias, V., González-Andrés, P., Fernández-Peña, L., Barbero, A., Núñez, L., & Villalobos, C. (2023) · Antioxidants · doi:10.3390/antiox12061282 · Cited by 21
Management of patients with Parkinson disease
Shin, J. Y., & Hendrix, C. C. (2013) · The Nurse Practitioner · doi:10.1097/01.npr.0000434090.96229.5c · Cited by 20
Chan, D. K. Y., Cordato, D. J., Bui, T., Mellick, G. D., & Woo, J. (2004) · Neuroepidemiology · doi:10.1159/000073970 · Cited by 20
Adenosine A2A antagonists: potential preventive and palliative treatment for Parkinson's disease
Morelli, M. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(03)00316-9 · Cited by 20
Smoking, alcohol, and coffee consumption preceding Parkinson’s disease
Deleu, D. (2001) · Neurology · doi:10.1212/wnl.56.7.984-a · Cited by 20
Zhao, Y., Zhou, Y., & Chen, J. (2023) · Chinese Journal of Traumatology · doi:10.1016/j.cjtee.2023.08.003 · Cited by 21
Nehlig, A., & Cunha, R. A. (2020) · Nutrients · doi:10.3390/nu12103141 · Cited by 19
Cao, R., Rossetti, G., Bauer, A., & Carloni, P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0126833 · Cited by 19
Gsandtner, I., & Freissmuth, M. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.026757 · Cited by 18
Cohort studies in health sciences librarianship.
Eldredge, J. D. (2002) · Europe PMC (PubMed Central) · Cited by 19
Cross-sensitization between caffeine- and l-dopa-induced behaviors in hemiparkinsonian mice
Yu, L., Schwarzschild, M. A., & Chen, J. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.09.036 · Cited by 19
Caffeine as a Neuroprotective Adenosine Receptor Antagonist
Dall'Igna, O. P. P., Souza, D. O., & Lara, D. R. (2004) · Annals of Pharmacotherapy · doi:10.1345/aph.1d307 · Cited by 19
Literature-Related Discovery (LRD)
Kostoff, R. N., Block, J. A., Solka, J. L., Briggs, M. B., Rushenberg, R. L., Stump, J. A., Johnson, D., Lyons, T. J., & Wyatt, J. R. (2007) · Defense Technical Information Center (DTIC) · doi:10.21236/ada473438 · Cited by 19
Indanone: a promising scaffold for new drug discovery against neurodegenerative disorders
Bansal, R., Singh, R., Dutta, T. S., Dar, Z. A., & Bajpai, A. (2024) · Drug Discovery Today · doi:10.1016/j.drudis.2024.104063 · Cited by 18
Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer′s Associated Tau Protein
Tira, R., Viola, G., Barracchia, C. G., Parolini, F., Munari, F., Capaldi, S., Assfalg, M., & D’Onofrio, M. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c01072 · Cited by 18
Tavares, A., Batis, J. C., Barret, O., Alagille, D., Vala, C., Kudej, G., Koren, A. O., Cosgrove, K., Nice, K., Kordower, J. H., et al. (2013) · Nuclear Medicine and Biology · doi:10.1016/j.nucmedbio.2012.12.005 · Cited by 18
Kinetic Modeling, Test–Retest, and Dosimetry of 123I-MNI-420 in Humans
Tavares, A., Batis, J. C., Papin, C., Jennings, D. L., Alagille, D., Russell, D., Vala, C., Lee, H. S., Baldwin, R. M., Zubal, I. G., et al. (2013) · Journal of Nuclear Medicine · doi:10.2967/jnumed.113.119933 · Cited by 18
Seliger, J., Žagar, V., Apih, T., Gregorovič, A., Latosińska, M., Olejniczak, G. A., & Latosińska, J. N. (2016) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2016.01.025 · Cited by 18
Ulanowska, K., Piosik, J., Gwizdek‐Wiśniewska, A., & Węgrzyn, G. (2007) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2007.05.025 · Cited by 18
Aromaticity of caffeine, xanthine and the dimethyl xanthines
Gibson, C. M., & Fowler, P. W. (2014) · Tetrahedron Letters · doi:10.1016/j.tetlet.2014.02.027 · Cited by 18
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Mishina, M., Ishii, K., Kimura, Y., Suzuki, M., Kitamura, S., Ishibashi, K., Sakata, M., Oda, K., Kobayashi, S., Kimura, K., et al. (2017) · Synapse · doi:10.1002/syn.21979 · Cited by 21
van Rensburg, H. D. J., Legoabe, L. J., Terre’Blanche, G., & der Walt, M. M. V. (2019) · MedChemComm · doi:10.1039/c8md00540k · Cited by 18
Barros, L., Eichwald, T., Solano, A. F., Scheffer, D. D. L., da Silva, R. A., Gaspar, J. M., & Latini, A. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.03.009 · Cited by 18
Gender-dependent effect of coffee consumption on tremor severity in de novo Parkinson’s disease
Cho, B., Choi, S., & Kim, B. C. (2019) · BMC Neurology · doi:10.1186/s12883-019-1427-y · Cited by 19
Living and dying with Parkinson's disease
Ross, G. W., & Abbott, R. D. (2014) · Movement Disorders · doi:10.1002/mds.25955 · Cited by 18
Self-citationRabin, M., Stevens‐Haas, C., Havrilla, E., Rosenstein, A. K., Toffey, B., Devi, T., Earnhardt, M. C., & Kurlan, R. (2015) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.12170 · Cited by 17
Norharman and harman in instant coffee and coffee substitutes
Alves, R. C., Mendes, E., Oliveira, M. B. P. P., & Casal, S. I. P. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.11.070 · Cited by 17
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Follmer, C. (2014) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2014.920235 · Cited by 18
You, D.-C., Kim, Y. S., Ha, A. W., Lee, Y.-N., Kim, S.-M., Kim, C.-H., Lee, S.-H., Choi, D., & Lee, J. (2011) · Toxicological Research · doi:10.5487/tr.2011.27.1.007 · Cited by 17
Hattori, N., Kikuchi, M., Adachi, N., Hewitt, D., Huyck, S. B., & Saito, T. (2016) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2016.08.020 · Cited by 17
Abbel, D., Åsvold, B. O., Kolberg, M., Selbæk, G., Noordam, R., & Skjellegrind, H. K. (2023) · Nutrients · doi:10.3390/nu15112469 · Cited by 16
Coffee, antioxidants, and brain inflammation
Rai, S. P., Ansari, A. H., Singh, D., & Singh, S. (2024) · Progress in brain research · doi:10.1016/bs.pbr.2024.06.005 · Cited by 20
Jia, H., Nogawa, S., Kawafune, K., Hachiya, T., Takahashi, S., Igarashi, M., Saito, K., & Kato, H. (2019) · BMC Genetics · doi:10.1186/s12863-019-0763-7 · Cited by 16
Ongini, E., Monopoli, A., Impagnatiello, F., Fredduzzi, S., Schwarzschild, M. A., & Chen, J. (2001) · Drug Development Research · doi:10.1002/ddr.1137 · Cited by 16
Caffeine induces age-dependent increases in brain complexity and criticality during sleep
Thölke, P., Arcand-Lavigne, M., Lajnef, T., Frenette, S., Carrier, J., & Jerbi, K. (2025) · Communications Biology · doi:10.1038/s42003-025-08090-z · Cited by 15
Tea, coffee and associated lifestyle factors
Hewlett, P., & Wadsworth, E. J. K. (2012) · British Food Journal · doi:10.1108/00070701211213500 · Cited by 15
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Onaolapo, O. J., Odeniyi, A. O., & Onaolapo, A. Y. (2021) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527320666210218082954 · Cited by 15
Apolipoprotein E Genotypes in Mexican Patients with Parkinson's Disease
Gallegos‐Arreola, M. P., Figuera, L. E., Ortiz, G. G., Jiménez-Gil, F. J., Ramírez-Vega, J., Ruíz‐Sandoval, J. L., Puebla‐Pérez, A. M., Troyo‐Sanromán, R., García‐Ortíz, J. E., Sánchez‐Corona, J., et al. (2009) · Disease Markers · doi:10.1155/2009/617863 · Cited by 15
Barati, S., Fabrizio, C., Strafella, C., Cascella, R., Caputo, V., Megalizzi, D., Peconi, C., Mela, J., Colantoni, L., Caltagirone, C., et al. (2022) · Genes · doi:10.3390/genes13081498 · Cited by 14
Marinesco bodies and substantia nigra neuron density in Parkinson's disease
Abbott, R. D., Nelson, J. S., Ross, G. W., Uyehara‐Lock, J. H., Tanner, C. M., Masaki, K., Launer, L. J., White, L. R., & Petrovitch, H. (2017) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12419 · Cited by 15
Self-citationCammisuli, D. M., Bonuccelli, U., Daniele, S., Martini, C., Fusi, J., & Franzoni, F. (2020) · Antioxidants · doi:10.3390/antiox9050380 · Cited by 17
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Sources of variation of energy and nutrient intake among adolescents in São Paulo, Brazil
Verly, E., Fisberg, R. M., César, C. L. G., & Marchioni, D. M. L. (2010) · Cadernos de Saúde Pública · doi:10.1590/s0102-311x2010001100014 · Cited by 14
Biocatalytic Production and Purification of the High-value Biochemical Paraxanthine
Mock, M. B., Mills, S. B., Cyrus, A., Campo, H., Dreischarf, T., Strock, S., & Summers, R. M. (2022) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-021-0301-0 · Cited by 14
Coffee and its Active Compounds are Neuroprotective
Kim, J., & Lee, K. W. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-409517-5.00046-2 · Cited by 14
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Meletis, C. D. (2006) · Alternative and Complementary Therapies · doi:10.1089/act.2006.12.7 · Cited by 14
Adenosine 2A Receptor Antagonists for the Treatment of Motor Symptoms in Parkinson's Disease
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Zhao, J., Wu, Z., Cai, F., Yu, X., & Song, Z. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1529197 · Cited by 14
Murata, T., Tago, K., Miyata, K., Moriwaki, Y., Misawa, H., Kobata, K., Nakazawa, Y., Tamura, H., & Funakoshi‐Tago, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010316 · Cited by 17
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Thanikachalam, S., Chandrasekharan, A., Vijayakumar, H., Chidambaram, S., & Bhaskar, L. V. (2014) · Cited by 13
Góngora-Alfaro, J. L. (2010) · Revista de Neurología · doi:10.33588/rn.5004.2009563 · Cited by 13
van Rensburg, H. D. J., Legoabe, L. J., Terre’Blanche, G., & der Walt, M. M. V. (2019) · Drug Research · doi:10.1055/a-0808-3993 · Cited by 13
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Chen, H., Hossain, M. A., Kim, J., & Cho, J. Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168864 · Cited by 13
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Douna, H., Bavelaar, B. M., Pellikaan, H., Olivier, B., & Pieters, T. (2012) · The Open Pharmacology Journal · doi:10.2174/1874143601206010012 · Cited by 13
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Kasabova-Angelova, A., Tzankova, D., Mitkov, J., Georgieva, M., Tzankova, V., Zlatkov, A., & Kondeva-Burdina, M. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180821153316 · Cited by 13
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Grujičić, S. Š., Vlajinac, H., Maksimovic, J. M., Marinković, J., Dzoljic, E. D., Ratkov, I., & Kostić, V. S. (2011) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2011.00593.x · Cited by 14
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Masino, S. A., & Dunwiddie, T. V. (2001) · Springer eBooks · doi:10.1007/978-3-662-09604-8_9 · Cited by 13
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Matinolli, M. (2009) · Cited by 13
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Cao, Z., Yuan, Y., White, A. J., Li, C., Luo, Z., D’Aloisio, A. A., Huang, X., Kaufman, J. D., Sandler, D. P., & Chen, H. (2024) · Environmental Health Perspectives · doi:10.1289/ehp13009 · Cited by 12
Australian Parkinson’s Genetics Study (APGS): pilot (n=1532)
Bivol, S., Mellick, G. D., Gratten, J., Parker, R., Mulcahy, A., Mosley, P. E., Poortvliet, P. C., Campos, A. I., Mitchell, B. L., García‐Marín, L. M., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-052032 · Cited by 12
Coffee aroma constituents and odorant metabolites in human urine
Wagenstaller, M., & Buettner, A. (2013) · Metabolomics · doi:10.1007/s11306-013-0581-2 · Cited by 12
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Pharmacological Bases of Coffee Nutrients for Diabetes Prevention
Oka, K. (2007) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.127.1825 · Cited by 12
Tennent, R., Ali, A., Wham, C. A., & Rutherfurd-Markwick, K. J. (2020) · Journal of Caffeine and Adenosine Research · doi:10.1089/caff.2020.0016 · Cited by 13
Góngora-Alfaro, J. L., Moo-Puc, R. E., Villanueva-Toledo, J. R., Álvarez-Cervera, F. J., Bata-García, J. L., Heredia-López, F. J., & Pineda, J. C. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.07.084 · Cited by 12
A Diet for Dopaminergic Neurons?
Giovanni, G. D. (2009) · Springer eBooks · doi:10.1007/978-3-211-92660-4_27 · Cited by 12
Blagov, A. V., Goncharov, A. G., Babich, O., Larina, V., Orekhov, A. N., & Melnichenko, A. А. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14112514 · Cited by 11
Yang, Y., Zhou, Z., Yi, L., Tan, B. J., & Tan, E.-K. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102381 · Cited by 13
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Raeis-Abdollahi, E., Raise‐Abdullahi, P., Rashidy‐Pour, A., Meamar, M., & Askari, H. (2024) · Progress in brain research · doi:10.1016/bs.pbr.2024.06.017 · Cited by 11
Bashir, B., Vishwas, S., Gupta, G., Paudel, K. R., Dureja, H., Kumar, P., Cho, H., Sugandhi, V. V., Kumbhar, P., Disouza, J., et al. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102693 · Cited by 11
Silva, R. S. D., Richetti, S. K., Tonial, E. M., Bogo, M. R., & Bonan, C. D. (2011) · Neurochemical Research · doi:10.1007/s11064-011-0577-0 · Cited by 11
Role of Adenosine A 2A Receptors in the Central Fatigue of Neurodegenerative Diseases
Alves, A. C. D. B., Bristot, V. J. D. O., Limana, M. D., Speck, A. E., Barros, L., Solano, A. F., & Aguiar, A. S. (2019) · Journal of Caffeine and Adenosine Research · doi:10.1089/caff.2019.0009 · Cited by 12
Predicting Parkinson’s Disease and Its Pathology via Simple Clinical Variables
Karabayir, İ., Butler, L., Goldman, S. M., Kamaleswaran, R., Güntürkün, F., Davis, R. L., Ross, G. W., Petrovitch, H., Masaki, K., Tanner, C. M., et al. (2021) · Journal of Parkinson s Disease · doi:10.3233/jpd-212876 · Cited by 11
Self-citationHuang, M., & Zhang, M. (2013) · Elsevier eBooks · doi:10.1533/9780857098672.3.513 · Cited by 11
Pienaar, I. S., & Chinnery, P. F. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.08.010 · Cited by 11
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Metadata
- Authors
- Ross, G. W.
- Affiliations
- United States Department of Veterans Affairs (US)
- Corresponding author
- Ross, G. Webster
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2000-05-24
- Volume
- 283
- Issue
- 20
- Pages
- 2674
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2128822428
- Cited by
- 778
- References
- 35
- Citations by year
- 2026: 8 · 2025: 24 · 2024: 28 · 2023: 34 · 2022: 22 · 2021: 39 · 2020: 26 · 2019: 35 · 2018: 26 · 2017: 36 · 2016: 24 · 2015: 29 · 2014: 39 · 2013: 37 · 2012: 36
- FWCI
- 17.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01hc005102-027, DAMD17-98-1-8621)
- National Institute on Aging (N01‐AG‐4‐2149)
- National Heart, Lung, and Blood Institute (N01 HC 05102, NO1-HC-05102)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- Parkinson's disease, coffee consumption, dietary caffeine, caffeine consumption, smoking, nicotinic acid, Honolulu Heart Program, Japanese-American men, disease incidence
- MeSH terms
- Aged, Caffeine, Coffee, Diet Surveys, Humans, Longitudinal Studies, Male, Middle Aged, Parkinson Disease, Regression Analysis, Risk Factors, Incidence
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