Cited by 2,049Dementia and Cognitive Impairment ResearchCognitive Functions and MemoryCognitive Abilities and Testing

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index; none of the 38 sources its claims cite is checked for support yet.

Effects of Cognitive Training Interventions With Older Adults: A Randomized Controlled Trial

Open access

Abstract

CONTEXT: Cognitive function in older adults is related to independent living and need for care. However, few studies have addressed whether improving cognitive functions might have short- or long-term effects on activities related to living independently. OBJECTIVE: To evaluate whether 3 cognitive training interventions improve mental abilities and daily functioning in older, independent-living adults. DESIGN: Randomized, controlled, single-blind trial with recruitment conducted from March 1998 to October 1999 and 2-year follow-up through December 2001. SETTING AND PARTICIPANTS: Volunteer sample of 2832 persons aged 65 to 94 years recruited from senior housing, community centers, and hospital/clinics in 6 metropolitan areas in the United States. INTERVENTIONS: Participants were randomly assigned to 1 of 4 groups: 10-session group training for memory (verbal episodic memory; n = 711), or reasoning (ability to solve problems that follow a serial pattern; n = 705), or speed of processing (visual search and identification; n = 712); or a no-contact control group (n = 704). For the 3 treatment groups, 4-session booster training was offered to a 60% random sample 11 months later. MAIN OUTCOME MEASURES: Cognitive function and cognitively demanding everyday functioning. RESULTS: Thirty participants were incorrectly randomized and were excluded from the analysis. Each intervention improved the targeted cognitive ability compared with baseline, durable to 2 years (P<.001 for all). Eighty-seven percent of speed-, 74% of reasoning-, and 26% of memory-trained participants demonstrated reliable cognitive improvement immediately after the intervention period. Booster training enhanced training gains in speed (P<.001) and reasoning (P<.001) interventions (speed booster, 92%; no booster, 68%; reasoning booster, 72%; no booster, 49%), which were maintained at 2-year follow-up (P<.001 for both). No training effects on everyday functioning were detected at 2 years. CONCLUSIONS: Results support the effectiveness and durability of the cognitive training interventions in improving targeted cognitive abilities. Training effects were of a magnitude equivalent to the amount of decline expected in elderly persons without dementia over 7- to 14-year intervals. Because of minimal functional decline across all groups, longer follow-up is likely required to observe training effects on everyday function.

Overview

Integrity signals

Registry

Crossref · 10.1001/jama.288.18.2271

Cites

52 of 52 references verified0 citation errors · 0 not checkable

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  • It may state two separate claims as one. 25
  • The quote only partly states this claim. 1
  • Probably not a substantial claim. 10
32 of 32
  • The paper relies on this without support.

    Many cognitive abilities and processes are linked to functional status, need for care, and quality of life.

    “Although there is substantial evidence that many cognitive abilities and processes are related to measures of functional status, need for care, and quality of life”
  • The paper relies on this without support.

    Few studies have tested whether improving cognition affects short- or long-term activities needed for independent living.

    “few studies have addressed whether improving cognitive functions might have shortor long-term effects on activities related to living independently.”
  • The paper relies on this without support.

    Neural plasticity persists throughout life.

    “neural plasticity endures across the lifespan”
  • The paper relies on this without support.

    Environmental cognitive stimulation is a key predictor of improving and maintaining cognitive functioning, even in old age.

    “cognitive stimulation in the environment is an important predictor of enhancement and maintenance of cognitive functioning, even in old age.”
  • The paper relies on this without support.

    Earlier cognitive training studies in older adults often gave little attention to suitable control groups, participant representativeness or heterogeneity, generalizability beyond specific laboratories, or adherence to training protocols.

    “prior cognitive training studies with older adults have often paid relatively little attention to the use of appropriate control groups, the representativeness or heterogeneity of participants, the generalizability of training findings beyond particular laboratories, or adherence of participants to training protocols.”
  • The paper relies on this without support.

    The wider effects of training on daily functioning in older adults have largely not been studied.

    “the broader implications of training on daily functioning in older adults, for the most part, have not been studied.”
  • The paper relies on this without support.

    Prior cognitive interventions, especially memory training, have not demonstrated two-year durability.

    “since prior interventions (especially memory) have not shown 2-year durability.”
  • The paper relies on this without support.

    Prior cognitive training research did not use intention-to-treat analyses and excluded participants who dropped out or were noncompliant.

    “prior cognitive training research has not used intention-to-treat analyses, instead excluding participants who dropped out or were noncompliant.”
  • The paper relies on this without support.

    Prior research did not use samples diverse in education and ethnicity.

    “In addition, prior research has not used diverse samples in terms of education and ethnicity.”
  • The paper relies on this without support.

    Several decades of cognitive science research show that transfer from cognitive training to real-world outcomes is difficult to obtain.

    “In addition to several decades of cognitive science research demonstrating the difficulty of obtaining such transfer”
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Research works printed but not linked: 7

  1. Recanzone, GH. Cerebral cortical plasticity: perception and skill acquisition. In: Gazzaniga, S., editor. The New Cognitive Neurosciences. Cambridge, Mass: The MIT Press; 2000. p. 237-247.
  2. Pietrucha, M., editors. Mobility and Transportation in the Elderly. New York, NY: Springer Publishing Co Inc; 2000. p. 213-251.
  3. Folstein MF, Flolstein SE, McHugh PR. "Minimental state ": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198. [PubMed: 1202204]
  4. Kliegl R, Smith J, Baltes PB. On the locus and process of magnification of age differences during mnemonic training. Dev Psychol 1990;26:894-904.
  5. Ball K, Beard B, Roenker D, Miller R, Ball D. Visual search: age and practice. Invest Ophthalmol Vis Sci 1988;29:448.
  6. Rey A. L'examen psychologique dans les cas d'encephalopathie tramatique. Archives de Psychologie 1941;28:21.
  7. Gonda, J.; Schaie, K. Schaie-Thurstone Mental Abilities Test: Word Series Test. Palo Alto, Calif: Consulting Psychologists Press; 1985.

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Metadata

Authors
Ball, K., Berch, D. B., Helmers, K. F., Jobe, J. B., Leveck, M. D., Marsiske, M., Morris, J. N., Rebok, G. W., Smith, D. M., Tennstedt, S. L., Unverzagt, F. W., Willis, S. L., & for the ACTIVE Study Group
Affiliations
  • University of Alabama at Birmingham (US)
  • National Institutes of Health (US)
  • University of Florida (US)
  • Johns Hopkins University (US)
  • Indiana University Bloomington (US)
  • New England Research Institutes (US)
  • Pennsylvania State University (US)
Venue
JAMA
Published
2002-11-13
Volume
288
Issue
18
Pages
2271
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W2118104542
Cited by
2,049
References
52
Citations by year
2026: 49 · 2025: 70 · 2024: 67 · 2023: 70 · 2022: 76 · 2021: 85 · 2020: 90 · 2019: 112 · 2018: 98 · 2017: 107 · 2016: 106 · 2015: 129 · 2014: 140 · 2013: 119 · 2012: 116
FWCI
17.56
Type
journal article
Language
en
Open access
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • IUScholarWorks (Indiana University) (submittedVersion)
Funders
  • Boston College
  • Georgia Institute of Technology
  • Johns Hopkins University (AG14282, AG14260, AG14263, AG014276, NR04507, U01 AG14260, NR04508)
  • Case Western Reserve University
  • University of South Carolina
  • New England Research Institutes (AG14282, AG14260, U01 AG14282, NR04508, AG14263, AG014276, NR04507)
  • School of Medicine, Indiana University ((U01 NR04508), NR04508)
  • National Institute on Aging (AG14263, U01 AG14282, U01AG014260, U01 AG 14263, U01AG14260, AG014276, U01-AG14289, NR04508, U01AG014289, U01AG014263, AG14260, U01AG014276, NR04507, AG14282, U01AG014282)
  • National Institute of Nursing Research (U01NR004507, NR04508, U01NR04507, U01NR004508, AG14263, AG014276, U01 NR04508, NR04507)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Keywords
cognitive training, older adults, independent living, memory training, reasoning training, processing speed, booster training, daily functioning, cognitive decline, verbal episodic memory
MeSH terms
Activities of Daily Living, Aged, Aged, 80 and over, Cognition, Humans, Memory, Mental Processes, Psychological Tests, Cognitive Behavioral Therapy, Single-Blind Method, Treatment Outcome

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