Global Skin Disease Morbidity and Mortality: An Update From the Global Burden of Disease Study 2013
Open accessAbstract
Importance: Disability secondary to skin conditions is substantial worldwide. The Global Burden of Disease Study 2013 includes estimates of global morbidity and mortality due to skin diseases. Objective: To measure the burden of skin diseases worldwide. Data Sources: For nonfatal estimates, data were found by literature search using PubMed and Google Scholar in English and Spanish for years 1980 through 2013 and by accessing administrative data on hospital inpatient and outpatient episodes. Data for fatal estimates were based on vital registration and verbal autopsy data. Study Selection: Skin disease data were extracted from more than 4000 sources including systematic reviews, surveys, population-based disease registries, hospital inpatient data, outpatient data, cohort studies, and autopsy data. Data metrics included incidence, prevalence, remission, duration, severity, deaths, and mortality risk. Data Extraction and Synthesis: Data were extracted by age, time period, case definitions, and other study characteristics. Data points were modeled with Bayesian meta-regression to generate estimates of morbidity and mortality metrics for skin diseases. All estimates were made with 95% uncertainty intervals. Main Outcomes and Measures: Disability-adjusted life years (DALYs), years lived with disability, and years of life lost from 15 skin conditions in 188 countries. Results: Skin conditions contributed 1.79% to the global burden of disease measured in DALYs from 306 diseases and injuries in 2013. Individual skin diseases varied in size from 0.38% of total burden for dermatitis (atopic, contact, and seborrheic dermatitis), 0.29% for acne vulgaris, 0.19% for psoriasis, 0.19% for urticaria, 0.16% for viral skin diseases, 0.15% for fungal skin diseases, 0.07% for scabies, 0.06% for malignant skin melanoma, 0.05% for pyoderma, 0.04% for cellulitis, 0.03% for keratinocyte carcinoma, 0.03% for decubitus ulcer, and 0.01% for alopecia areata. All other skin and subcutaneous diseases composed 0.12% of total DALYs. Conclusions and Relevance: Skin and subcutaneous diseases were the 18th leading cause of global DALYs in Global Burden of Disease 2013. Excluding mortality, skin diseases were the fourth leading cause of disability worldwide.
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Skin diseases are the fourth leading cause of consultations in health centres.
“While SDs are the fourth leading cause of consultations in health centres [11,12]”
In 2013, skin conditions accounted for 1.79% of total global DALYs across 306 diseases and injuries.
“In 2013, skin conditions contributed 1.79% to the total global burden of disease measured in DALYs across 306 diseases and injuries.”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [6]
Dermatitis caused the greatest burden among the assessed skin disease categories, at 9.3 million DALYs.
“Dermatitis (encompassing atopic, seborrheic, and contact types) resulted in the greatest burden of the skin conditions, costing 9.3 million DALYs”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [6]
Melanoma causes the greatest skin disease burden in resource-rich regions such as Australia and North America.
“Melanoma causes the greatest burden in resource-rich regions such as Australia and North America”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [6]
Infectious skin conditions such as viral warts, pyoderma, cellulitis, and scabies cause greater burden among children.
“infectious causes of skin conditions, such as viral warts, pyoderma, cellulitis, and scabies, causing greater burden among children”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [6]
Older persons suffer disability burden from psoriasis, alopecia areata, urticaria, fungal skin diseases, and decubitus ulcers.
“Persons of older age suffer disability burden from psoriasis, alopecia areata, urticaria, fungal skin diseases, and decubitus ulcers.”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [6]
Dermatitis has the highest DALY rate in Sub-Saharan Africa.
“dermatitis has the highest DALY rate in Sub-Saharan Africa”
From Global Burden of Skin Disease: Inequities and Innovations (2017) · cites this paper as [6]
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Cites
Murray, C. J. L., Vos, T., Lozano, R., Naghavi, M., Flaxman, A. D., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61689-4 · Cited by 8,888 · see citing works
Self-citationVos, T., Barber, R. M., Bell, B., Bertozzi-Villa, A., Biryukov, S., Bolliger, I., Charlson, F., Davis, A., Degenhardt, L., Dicker, D., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60692-4 · Cited by 6,414 · see citing works
Self-citationMurray, C. J. L., Barber, R. M., Foreman, K. J., Özgören, A. A., Abd-Allah, F., Abera, S. F., Aboyans, V., Abraham, J. P., Abubakar, I., Abu-Raddad, L. J., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)61340-x · Cited by 1,966 · see citing works
Measuring the global burden of disease
Murray, C. J. L., & Lopez, A. D. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1201534 · Cited by 1,818 · see citing works
Hay, R. J., Johns, N. E., Williams, H. C., Bolliger, I. W., Dellavalle, R. P., Margolis, D. J., Marks, R., Naldi, L., Weinstock, M. A., Wulf, S. K., et al. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.446 · Cited by 1,706 · cited 2× · see citing works
“J Eur Acad Dermatol Venereol 2007;21(5):643-9.”
Self-citationDisability weights for the Global Burden of Disease 2013 study
Salomon, J. A., Haagsma, J. A., Davis, A., de Noordhout, C. M., Polinder, S., Havelaar, A. H., Cassini, A., Devleesschauwer, B., Kretzschmar, M., Speybroeck, N., et al. (2015) · The Lancet Global Health · doi:10.1016/s2214-109x(15)00069-8 · Cited by 1,217 · see citing works
Self-citationGBD 2010: design, definitions, and metrics
Murray, C. J., Ezzati, M., Flaxman, A. D., Lim, S., Lozano, R., Michaud, C., Naghavi, M., Salomon, J. A., Shibuya, K., Vos, T., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61899-6 · Cited by 1,103 · cited 7× · see citing works
“J Eur Acad Dermatol Venereol 2007;21(2):163-8.”
BackgroundInfluentialSelf-citationKnowledge, moral claims and the exercise of power in global health
Shiffman, J. (2014) · International Journal of Health Policy and Management · doi:10.15171/ijhpm.2014.120 · Cited by 243 · see citing works
Global Burden of Skin Disease as Reflected in <i>Cochrane Database of Systematic Reviews</i>
Karimkhani, C., Boyers, L. N., Prescott, L., Welch, V., Delamere, F. M., Nasser, M., Zaveri, A., Hay, R. J., Vos, T., Murray, C. J. L., et al. (2014) · JAMA Dermatology · doi:10.1001/jamadermatol.2014.709 · Cited by 87 · see citing works
Self-citationThe global challenge for skin health
Hay, R. J., Augustin, M., Griffiths, C. E. M., Sterry, W., & the Board of the International League of Dermatological Societies and the Grand Challenges Consultation groups (2015) · British Journal of Dermatology · doi:10.1111/bjd.13854 · Cited by 78 · see citing works
Self-citationLekalakala, P. T., Khammissa, R. A. G., Kramer, B., Ayo-Yusuf, O. A., Lemmer, J., & Feller, L. (2015) · Journal of Skin Cancer · doi:10.1155/2015/167847 · Cited by 70 · see citing works
Global health metrics needs collaboration and competition
Rudan, I., & Chan, K. Y. (2014) · The Lancet · doi:10.1016/s0140-6736(14)62006-7 · Cited by 62 · see citing works
A clinicopathologic review of lethal nonmelanoma skin cancers in Western Australia
Nolan, R. C., Chan, M. T.-L., & Heenan, P. J. (2004) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2004.08.016 · Cited by 39 · see citing works
CUTANEOUS MANIFESTATIONS OF SYSTEMIC DISEASES
Robson, K. J., & Piette, W. W. (1998) · Medical Clinics of North America · doi:10.1016/s0025-7125(05)70419-3 · Cited by 36 · see citing works
Freeman, E. E. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.355 · Cited by 20 · see citing works
Neal, R. D., Cannings-John, R. L., Hood, K., Sowden, J. M., Lawrence, H., Jones, C. H., & Jones, J. H. (2008) · Family Practice · doi:10.1093/fampra/cmn036 · Cited by 15 · see citing works
The International Foundation for Dermatology
Fuller, L. C., & Hay, R. J. (2015) · British Journal of Dermatology · doi:10.1111/bjd.13856 · Cited by 4 · see citing works
Self-citation
Flagged first, then by citations
1 of the 19 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [14]Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015; 386(9995): 743- 800. 26063472 PMC4561509
Cited by
Sorted by citations
Weidinger, S., Beck, L. A., Bieber, T., Kabashima, K., & Irvine, A. D. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0001-z · Cited by 1,549 · see citing works
National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study
Parisi, R., Iskandar, I. Y. K., Kontopantelis, E., Augustin, M., Griffiths, C. E. M., & Ashcroft, D. M. (2020) · BMJ · doi:10.1136/bmj.m1590 · Cited by 1,195 · see citing works
A deep learning system for differential diagnosis of skin diseases
Liu, Y., Jain, A., Eng, C., Way, D. H., Lee, K., Bui, P., Kanada, K., de Oliveira Marinho, G., Gallegos, J., Gabriele, S., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0842-3 · Cited by 853 · see citing works
Martinengo, L., Olsson, M. M., Bajpai, R. C., Soljak, M., Upton, Z., Schmidtchen, A., Car, J., & Järbrink, K. (2018) · Annals of Epidemiology · doi:10.1016/j.annepidem.2018.10.005 · Cited by 724 · see citing works
The global burden of atopic dermatitis: lessons from the Global Burden of Disease Study 1990–2017*
Laughter, M. R., Maymone, M. B. C., Mashayekhi, S., Arents, B. W. M., Karimkhani, C., Langan, S., Dellavalle, R. P., & Flohr, C. (2020) · British Journal of Dermatology · doi:10.1111/bjd.19580 · Cited by 644 · see citing works
Self-citationGuidelines of care for the management of acne vulgaris
Reynolds, R. V., Yeung, H., Cheng, C. E., Cook-Bolden, F., Desai, S. R., Druby, K. M., Freeman, E. E., Keri, J. E., Stein Gold, L. F., Tan, J. K. L., et al. (2024) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2023.12.017 · Cited by 518 · see citing works
Damiani, G. B., Bragazzi, N. L., Aksut, C. K., Wu, D., Alicandro, G., McGonagle, D., Guo, C., Dellavalle, R. P., Grada, A. A., Wong, P., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.743180 · Cited by 383 · see citing works
Self-citationGlobal Burden of Skin Disease: Inequities and Innovations
Seth, D., Cheldize, K., Brown, D., & Freeman, E. E. (2017) · Current Dermatology Reports · doi:10.1007/s13671-017-0192-7 · Cited by 366 · see citing works
Karimkhani, C., Colombara, D. V., Drucker, A. M., Norton, S. A., Hay, R. J., Engelman, D., Steer, A. C., Whitfeld, M. J., Naghavi, M., & Dellavalle, R. P. (2017) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(17)30483-8 · Cited by 363 · see citing works
Self-citationMaverakis, E. M., Marzano, A. V., Le, S. T., Callen, J. P., Brüggen, M., Guenova, E., Dissemond, J., Shinkai, K., & Langan, S. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0213-x · Cited by 313 · see citing works
Self-citationAcne, the Skin Microbiome, and Antibiotic Treatment
Xu, H., & Li, H. (2019) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-00417-3 · Cited by 294 · see citing works
United States burden of melanoma and non-melanoma skin cancer from 1990 to 2019
Aggarwal, P., Knabel, P., & Fleischer, A. B. (2021) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2021.03.109 · Cited by 286 · see citing works
IoT-based telemedicine for disease prevention and health promotion: State-of-the-Art
Albahri, A. S., Alwan, J. K., Taha, Z. K., Ismail, S. F., Hamid, R. A., Zaidan, A. A., Albahri, O. S., Zaidan, B. B., Alamoodi, A. H., & Alsalem, M. A. (2020) · Journal of Network and Computer Applications · doi:10.1016/j.jnca.2020.102873 · Cited by 294 · see citing works
Hameed, N., Shabut, A. M., Ghosh, M. K., & Hossain, M. A. (2019) · Expert Systems with Applications · doi:10.1016/j.eswa.2019.112961 · Cited by 217 · see citing works
The progress and perspectives of terahertz technology for diagnosis of neoplasms: a review
Zaytsev, K. I., Dolganova, I. N., Chernomyrdin, N. V., Katyba, G. M., Gavdush, A. A., Черкасова, О. П., Komandin, G. A., Анатольевна, Щ. М., Khodan, A. N., Ponomarev, D. S., et al. (2019) · Journal of Optics · doi:10.1088/2040-8986/ab4dc3 · Cited by 208 · see citing works
Boguniewicz, M., Alexis, A. F., Beck, L. A., Block, J. K., Eichenfield, L. F., Fonacier, L. S., Guttman‐Yassky, E., Paller, A. S., Pariser, D. M., Silverberg, J. I., et al. (2017) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2017.08.005 · Cited by 190 · see citing works
Self-citationPressure ulcer/injury classification today: An international perspective
Kottner, J., Cuddigan, J., Carville, K., Balzer, K., Berlowitz, D. R., Law, S., Litchford, M. D., Mitchell, P., Moore, Z. E. H., Pittman, J. A., et al. (2020) · Journal of Tissue Viability · doi:10.1016/j.jtv.2020.04.003 · Cited by 194 · see citing works
Engineering Bioactive Scaffolds for Skin Regeneration
Hosseini, M., & Shafiee, A. (2021) · Small · doi:10.1002/smll.202101384 · Cited by 181 · see citing works
Reviewing the global burden of acne: how could we improve care to reduce the burden?*
Layton, A., Thiboutot, D. M., & Tan, J. K. L. (2020) · British Journal of Dermatology · doi:10.1111/bjd.19477 · Cited by 173 · see citing works
Extracellular vesicles as modulators of wound healing
Cabral, J., Ryan, A. E., Griffin, M. D., & Ritter, T. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.01.018 · Cited by 168 · see citing works
The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019
Yakupu, A., Aimaier, R., Yuan, B., Chen, B., Cheng, J., Zhao, Y., Peng, Y., Dong, J., & Lu, S. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1145513 · Cited by 177 · see citing works
Putting the burden of skin diseases on the global map
Flohr, C., & Hay, R. J. (2021) · British Journal of Dermatology · doi:10.1111/bjd.19704 · Cited by 164 · see citing works
Self-citationMartins‐Melo, F. R., Carneiro, M., Ramos, A. N., Heukelbach, J., Ribeiro, A. L. P., & Werneck, G. L. (2018) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006559 · Cited by 160 · see citing works
Seborrheic dermatitis—Looking beyond Malassezia
Wikramanayake, T. C., Borda, L. J., Miteva, M. I., & Paus, R. (2019) · Experimental Dermatology · doi:10.1111/exd.14006 · Cited by 164 · see citing works
Scheinman, P. L., Vocanson, M., Thyssen, J. P., Johansen, J. D., Nixon, R. L., Dear, K., Botto, N. C., Morot, J., & Goldminz, A. M. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00271-4 · Cited by 163 · see citing works
Aloe vera : A Medicinal Plant Used in Skin Wound Healing
Liang, J., Cui, L., Li, J., Guan, S., Zhang, K., & Li, J. (2020) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2020.0236 · Cited by 144 · see citing works
Microfluidic Skin‐on‐a‐Chip Models: Toward Biomimetic Artificial Skin
Sutterby, E., Thurgood, P., Baratchi, S., Khoshmanesh, K., & Pirogova, E. (2020) · Small · doi:10.1002/smll.202002515 · Cited by 142 · see citing works
How, K. N., Yap, W. H., Lim, C. L. H., Goh, B. H., & Lai, Z. W. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01105 · Cited by 138 · see citing works
Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
Lee, J., van der Valk, W. H., Serdy, S. A., Deakin, C., Kim, J., Le, A. P., & Koehler, K. R. (2022) · Nature Protocols · doi:10.1038/s41596-022-00681-y · Cited by 132 · see citing works
Sleep Disturbances and Atopic Dermatitis: Relationships, Methods for Assessment, and Therapies
Bawany, F., Northcott, C. A., Beck, L. A., & Pigeon, W. R. (2020) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2020.12.007 · Cited by 134 · see citing works
Chen, H., Zhang, T., Yin, X. L., Man, J., Yang, X., & Lü, M. (2021) · British Journal of Dermatology · doi:10.1111/bjd.20882 · Cited by 138 · see citing works
Zagórska-Dziok, M., & Sobczak, M. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12050396 · Cited by 126 · see citing works
Costa, C. S., Bagatin, E., Martimbianco, A. L. C., da Silva, E. M., Lúcio, M. M., Magin, P. J., & Riera, R. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009435.pub2 · Cited by 115 · see citing works
Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis
Mack, M. R., Brestoff, J. R., Berrien-Elliott, M. M., Trier, A. M., Yang, T.-L. B., McCullen, M. V. D., Collins, P. L., Niu, H., Bodet, N. D., Wagner, J. A., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay1005 · Cited by 109 · see citing works
Deciphering UV‐induced DNA Damage Responses to Prevent and Treat Skin Cancer
Lee, J. W., Ratnakumar, K., Hung, K., Rokunohe, D., & Kawasumi, M. (2020) · Photochemistry and Photobiology · doi:10.1111/php.13245 · Cited by 112 · see citing works
Tizek, L., Schielein, M. C., Seifert, F., Biedermann, T., Böhner, A., & Zink, A. (2019) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15494 · Cited by 108 · see citing works
Castillo, D. E., Nanda, S., & Keri, J. E. (2018) · Dermatology and Therapy · doi:10.1007/s13555-018-0275-9 · Cited by 103 · see citing works
The socioeconomics of atopic dermatitis
Chung, J., & Simpson, E. L. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.12.017 · Cited by 104 · see citing works
Expanding the applications of microneedles in dermatology
Sabri, A. H. B., Ogilvie, J., Hamid, K. A., Shpadaruk, V., McKenna, J., Segal, J. I., Scurr, D. J., & Marlow, M. (2019) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2019.05.001 · Cited by 101 · see citing works
Detection and Classification of Skin Cancer by Using a Parallel CNN Model
Rezaoana, N., Hossain, M. S., & Andersson, K. (2020) · IEEE International Women in Engineering (WIE) Conference on Electrical and Computer Engineering (WIECON-ECE) · doi:10.1109/wiecon-ece52138.2020.9397987 · Cited by 101 · see citing works
Cannabinoids in the Pathophysiology of Skin Inflammation
Scheau, C., Bădărău, I. A., Mihai, L.-G., Scheau, A.-E., Costache, D. O., Constantin, C., Călina, D. C., Căruntu, C., Costache, R. S., & Căruntu, A. (2020) · Molecules · doi:10.3390/molecules25030652 · Cited by 98 · see citing works
Topical delivery of siRNA into skin using ionic liquids
Dharamdasani, V., Mandal, A., Qi, Q. M., Suzuki, I., Bentley, M. V. L. B., & Mitragotri, S. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.04.038 · Cited by 100 · see citing works
Urban, K., Chu, S., Giesey, R. L., Mehrmal, S., Uppal, P., Nedley, N., & Delost, G. R. (2020) · JAAD International · doi:10.1016/j.jdin.2020.10.002 · Cited by 98 · see citing works
Urban, K., Chu, S., Giesey, R. L., Mehrmal, S., Uppal, P., Delost, M. E., & Delost, G. R. (2020) · JAAD International · doi:10.1016/j.jdin.2020.10.006 · Cited by 95 · see citing works
Fairness of Classifiers Across Skin Tones in Dermatology
Kinyanjui, N. M., Odonga, T., Cintas, C., Codella, N., Panda, R., Sattigeri, P., & Varshney, K. R. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-59725-2_31 · Cited by 94 · see citing works
Pangti, R., Mathur, J., Chouhan, V., Kumar, S. M., Rajput, L., Shah, S., Gupta, A., Dixit, A., Dholakia, D., Gupta, S., et al. (2020) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.16967 · Cited by 87 · see citing works
Reframing racial and ethnic disparities in atopic dermatitis in Black and Latinx populations
Croce, E. A., Levy, M., Adamson, A., & Matsui, E. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.09.015 · Cited by 62 · see citing works
Skin organoids: a new human model for developmental and translational research
Lee, J., & Koehler, K. R. (2021) · Experimental Dermatology · doi:10.1111/exd.14292 · Cited by 85 · see citing works
Li, Y., Yang, Y., Chen, H., Mei, L., & Zeng, X. (2021) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2021.07.002 · Cited by 85 · see citing works
Marks, D. H., Penzi, L. R., Ibler, E., Manatis-Lornell, A. J., Hagigeorges, D., Yasuda, M. R., Drake, L. A., & Senna, M. M. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0405-2 · Cited by 82 · see citing works
Personalized medicine—concepts, technologies, and applications in inflammatory skin diseases
Litman, T. (2019) · Apmis · doi:10.1111/apm.12934 · Cited by 81 · see citing works
Microalgae as Potential Anti-Inflammatory Natural Product Against Human Inflammatory Skin Diseases
Choo, W., Teoh, M., Phang, S., Convey, P., Yap, W.-H., Goh, B. H., & Beardall, J. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01086 · Cited by 78 · see citing works
Yadav, P. R., Munni, M. N., Campbell, L., Mostofa, G., Dobson, L. J., Shittu, M., Pattanayek, S. K., Uddin, M. J., & Das, D. B. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13081132 · Cited by 77 · see citing works
Ko, K. I., Merlet, J., DerGarabedian, B. P., Huang, Z., Suzuki-Horiuchi, Y., Hedberg, M. L., Hu, E. Y., Nguyen, A., Prouty, S. M., Alawi, F., et al. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abj0324 · Cited by 76 · see citing works
Cárcamo-Martínez, Á., Mallon, B., Anjani, Q. K., Domínguez‐Robles, J., Utomo, E., Vora, L. K., Tekko, I. A., Larrañeta, E., & Donnelly, R. F. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.120152 · Cited by 74 · see citing works
Probiotics: Protecting Our Health from the Gut
Varela-Trinidad, G. U., Domínguez-Díaz, C., Solórzano-Castanedo, K., Íñiguez-Gutiérrez, L., Hernández-Flores, T. D. J., & Fafutis‐Morris, M. (2022) · Microorganisms · doi:10.3390/microorganisms10071428 · Cited by 78 · see citing works
Hypofractionated radiation therapy for basal and squamous cell skin cancer: A meta-analysis
Zaorsky, N. G., Lee, C. T., Zhang, E., Keith, S. W., & Galloway, T. J. (2017) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2017.08.011 · Cited by 73 · see citing works
The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin
Lin, M.-H., Hung, C., Sung, H., Yang, S.-C., Yu, H., & Fang, J. (2021) · Journal of Food and Drug Analysis · doi:10.38212/2224-6614.1151 · Cited by 76 · see citing works
The Burden of Skin and Subcutaneous Diseases in the United States From 1990 to 2017
Laughter, M. R., Maymone, M. B. C., Karimkhani, C., Rundle, C. W., Hu, S., Wolfe, S. M., Abuabara, K., Hollingsworth, P., Weintraub, G. S., Dunnick, C. A., et al. (2020) · JAMA Dermatology · doi:10.1001/jamadermatol.2020.1573 · Cited by 71 · see citing works
Self-citationConsensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology
Bagatin, E., Costa, C. S., Rocha, M., Picosse, F. R., Kamamoto, C. S. L., Pirmez, R., Ianhez, M., & Miot, H. A. (2020) · Anais Brasileiros de Dermatologia · doi:10.1016/j.abd.2020.09.001 · Cited by 77 · see citing works
Lipid Based Nanocarriers: Promising Drug Delivery System for Topical Application
Patel, D., Patel, B., & Thakkar, H. P. (2021) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.202000264 · Cited by 71 · see citing works
Dissolving Candlelit Microneedle for Chronic Inflammatory Skin Diseases
Ohn, J., Jang, M., Kang, B. M., Yang, H., Hong, J. T., Kim, K. H., Kwon, O., & Jung, H. (2021) · Advanced Science · doi:10.1002/advs.202004873 · Cited by 71 · see citing works
A Skin Disease Classification Model Based on DenseNet and ConvNeXt Fusion
Wei, M., Wu, Q., Ji, H., Wang, J., Lyu, T., Liu, J., & Zhao, L. Y. (2023) · Electronics · doi:10.3390/electronics12020438 · Cited by 74 · see citing works
Artificial intelligence-assisted smartphone-based sensing for bioanalytical applications: A review
Yang, Y., Xu, F., Chen, J., Tao, C., Li, Y., Chen, Q., Tang, S. N., Lee, H. K., & Shen, W. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115233 · Cited by 69 · see citing works
A Computer-aided diagnosis system for classifying prominent skin lesions using machine learning
Hameed, N., Shabut, A. M., & Hossain, M. A. (2018) · Computer Science and Electronic Engineering Conference · doi:10.1109/ceec.2018.8674183 · Cited by 73 · see citing works
Yi, X., Bao, W., Zhou, J., Zhao, Q., Hong, S.-Z., Yang, B., Ren, J., Wang, P., Yin, B., Chu, C., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.861053 · Cited by 67 · see citing works
Association of Race/Ethnicity and Sex With Differences in Health Care Use and Treatment for Acne
Barbieri, J. S., Shin, D. B., Wang, S., Margolis, D. J., & Takeshita, J. (2020) · JAMA Dermatology · doi:10.1001/jamadermatol.2019.4818 · Cited by 65 · see citing works
Gustafson, E., Pacheco, J., Wehbe, F., Silverberg, J., & Thompson, W. (2017) · 2017 IEEE International Conference on Healthcare Informatics (ICHI) · doi:10.1109/ichi.2017.31 · Cited by 65 · see citing works
Self-citationThe global burden of decubitus ulcers from 1990 to 2019
Zhang, X., Zhu, N., Li, Z., Xie, X., Liu, T., & Ouyang, G. (2021) · Scientific Reports · doi:10.1038/s41598-021-01188-4 · Cited by 64 · see citing works
Bowen, A. C., Carapetis, J. R., Currie, B. J., Fowler, V. G., Chambers, H. F. “., & Tong, S. Y. C. (2017) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofx232 · Cited by 62 · see citing works
Skin aging: the dermal perspective
Strnadová, K., Sandera, V., Dvořánková, B., Kodet, O., Dušková, M., Smetana, K., & Lacina, L. (2019) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2019.04.005 · Cited by 62 · see citing works
The link between atopic dermatitis and asthma-immunological imbalance and beyond
Yaneva, M., & Darlenski, R. (2021) · Asthma Research and Practice · doi:10.1186/s40733-021-00082-0 · Cited by 60 · see citing works
Topical Antiseptic Formulations for Skin and Soft Tissue Infections
Hoang, T. P. N., Ghori, M. U., & Conway, B. R. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13040558 · Cited by 60 · see citing works
Nanocarriers for treatment of dermatological diseases: Principle, perspective and practices
Ramanunny, A. K., Wadhwa, S., Gulati, M., Singh, S. K., Kapoor, B., Dureja, H., Chellappan, D. K., Anand, K., Dua, K., Khursheed, R., et al. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173691 · Cited by 60 · see citing works
Hawro, T., Przybyłowicz, K., Spindler, M., Hawro, M., Steć, M., Altrichter, S., Weller, K., Magerl, M. A. K., Reidel, U., Alarbeed, E., et al. (2020) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2020.08.035 · Cited by 59 · see citing works
The Economics Burden of Atopic Dermatitis
Adamson, A. S. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-64804-0_8 · Cited by 57 · see citing works
Skin CanceR Brachytherapy vs External beam radiation therapy (SCRiBE) meta-analysis
Zaorsky, N. G., Lee, C. T., Zhang, E., & Galloway, T. J. (2018) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2017.12.029 · Cited by 56 · see citing works
Noddeland, H. K., Lind, M. L., Jensen, L. B., Petersson, K., Skak‐Nielsen, T., Larsen, F. H., Malmsten, M., & Heinz, A. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.12.015 · Cited by 56 · see citing works
Abbas, S., Ahmed, F., Khan, W. A., Ahmad, M., Khan, M. A., & Ghazal, T. M. (2025) · Scientific Reports · doi:10.1038/s41598-024-83966-4 · Cited by 55 · see citing works
Liu, H., Yu, H., Xia, J., Liu, L., Liu, G. J., Sang, H., & Peinemann, F. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011368.pub2 · Cited by 55 · see citing works
Faye, O., Bagayoko, C., Dicko, A., Cissé, L., Berthé, S., Traoré, B., Fofana, Y., Niang, M., Traoré, S., Karabinta, Y., et al. (2018) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed3030088 · Cited by 54 · see citing works
Huang, K., Jiang, Z., Li, Y., Wu, Z., Wu, X., Zhu, W., Chen, M., Zhang, Y., Zuo, K., Li, Y., et al. (2021) · Journal of Medical Internet Research · doi:10.2196/26025 · Cited by 54 · see citing works
Dermal Drug Delivery of Phytochemicals with Phenolic Structure via Lipid-Based Nanotechnologies
Gugleva, V., Ivanova, N. A., Sotirova, Y., & Andonova, V. (2021) · Pharmaceuticals · doi:10.3390/ph14090837 · Cited by 54 · see citing works
Biologic Therapy for Atopic Dermatitis: Moving Beyond the Practice Parameter and Guidelines
Boguniewicz, M. (2017) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2017.08.031 · Cited by 53 · see citing works
Shen, M., Xiao, Y., Jing, D., Zhang, G., Su, J., Lin, S., Chen, X., & Liu, H. (2022) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2022.04.006 · Cited by 51 · see citing works
Yi, X., Zhou, J., Xu, B.-N., Li, Y., Bao, W., Cheng, X. L., He, Y., Xu, C. P., Ren, J., Zheng, Y. R., et al. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.861115 · Cited by 51 · see citing works
Hữu, S. N., Nguyen, L. H., Vu, G. T., Nguyen, C. T., Le, T. H. T., Tran, B. X., Latkin, C. A., Ho, C. S. H., & Ho, R. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16030305 · Cited by 50 · see citing works
Guthold, R., Johansson, E. W., Mathers, C. D., & Ross, D. A. (2021) · BMJ Global Health · doi:10.1136/bmjgh-2021-004996 · Cited by 49 · see citing works
Dong, W., An, J. W., Yu, M., Yin, P., Xu, T., Liu, B., Zuberbier, T., Zhao, Z., & Zhou, M. (2021) · World Allergy Organization Journal · doi:10.1016/j.waojou.2021.100604 · Cited by 48 · see citing works
Kumar, P., Ramachandran, S., Das, S., Bhattacharya, S. N., & Taneja, B. (2023) · Mycopathologia · doi:10.1007/s11046-023-00720-6 · Cited by 49 · see citing works
Yotsu, R. R., Fuller, L. C., Murdoch, M. E., van Brakel, W. H., Revankar, C. R., Barogui, M. Y. T., Ruiz-Postigo, J. A., Dagne, D. A., Asiedu, K. B., & Hay, R. J. (2023) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0011357 · Cited by 48 · see citing works
Self-citationUpdating the Fitzpatrick Classification: The Skin Color and Ethnicity Scale
Coleman, W. P., Mariwalla, K., & Grimes, P. E. (2023) · Dermatologic Surgery · doi:10.1097/dss.0000000000003860 · Cited by 48 · see citing works
Accelerating Patterned Vascularization Using Granular Hydrogel Scaffolds and Surgical Micropuncture
Ataie, Z., Horchler, S., Jaberi, A., Koduru, S. V., El-Mallah, J. C., Sun, M., Kheirabadi, S., Kedzierski, A., Risbud, A., Silva, A. R. A. E., et al. (2023) · Small · doi:10.1002/smll.202307928 · Cited by 49 · see citing works
Stimuli-responsive drug delivery systems for inflammatory skin conditions
Gade, L., Boyd, B. J., Malmsten, M., & Heinz, A. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.08.037 · Cited by 48 · see citing works
The Challenge of Developing a Single-Dose Treatment for Scabies
Bernigaud, C., Samarawickrama, G. R., Jones, M. K., Gasser, R. B., & Fischer, K. (2019) · Trends in Parasitology · doi:10.1016/j.pt.2019.08.002 · Cited by 48 · see citing works
An Intelligent Computer-Aided Scheme for Classifying Multiple Skin Lesions
Hameed, N., Hameed, F., Shabut, A. M., Khan, S., Cirstea, S., & Hossain, A. (2019) · Computers · doi:10.3390/computers8030062 · Cited by 48 · see citing works
Association between atopic disease and anemia in pediatrics: a cross-sectional study
Rhew, K., & Oh, J. M. (2019) · BMC Pediatrics · doi:10.1186/s12887-019-1836-5 · Cited by 48 · see citing works
Mahant, S., Rao, R., Souto, E. B., & Nanda, S. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2020.1772750 · Cited by 48 · see citing works
Blanchard, G., Amarov, B., Fratti, M., Salamin, K., Bontems, O., Chang, Y., Sabou, M., Künzle, N., Monod, M., & Guenova, E. (2023) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.19253 · Cited by 47 · see citing works
Hydrogels: a promising therapeutic platform for inflammatory skin diseases treatment
Cao, H.-L., Wang, M., Ding, J., & Lin, Y. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb00887a · Cited by 48 · see citing works
- Authors
- Karimkhani, C., Dellavalle, R. P., Coffeng, L. E., Flohr, C., Hay, R. J., Langan, S. M., Nsoesie, E. O., Ferrari, A. J., Erskine, H. E., Silverberg, J. I., Vos, T., & Naghavi, M.
- Affiliations
- University Hospitals Case Western Medical Center, Cleveland, Ohio
- Colorado School of Public Health (US)
- University of Washington (US)
- King's College London (GB)
- King's College Hospital (GB)
- London School of Hygiene & Tropical Medicine (GB)
- The University of Queensland (AU)
- Northwestern University (US)
- ORCID
- Venue
- JAMA Dermatology
- Publisher
- American Medical Association (AMA)
- Published
- 2017-05-01
- Volume
- 153
- Issue
- 5
- Pages
- 406
- ISSN
- 2168-6068 (ISSN-L)
- PMC
- PMC5817488
- OpenAlex
- W2594455611
- Cited by
- 742
- References
- 19
- Citations by year
- 2026: 80 · 2025: 88 · 2024: 110 · 2023: 99 · 2022: 79 · 2021: 82 · 2020: 96 · 2019: 53 · 2018: 41 · 2017: 13
- FWCI
- 63.05
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- JAMA Dermatology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion, other-oa)
- RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Research Portal (King's College London) (submittedVersion, cc-by)
- RePub (Erasmus University Rotterdam) (submittedVersion)
- Funders
- Bill and Melinda Gates Foundation
- National Institute for Health and Care Research (NIHR/CS/010/014)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
- Health Sciences › Health Professions › Health Information Management › Global Health and Epidemiology
- Keywords
- skin diseases, global burden of disease, disability-adjusted life years, years lived with disability, years of life lost, morbidity, mortality, atopic dermatitis, contact dermatitis, seborrheic dermatitis, acne, psoriasis, urticaria, viral skin infections, fungal skin infection, scabies, melanoma, pyoderma, cellulitis
- MeSH terms
- Global Burden of Disease, Adolescent, Adult, Aged, Aged, 80 and over, Bayes Theorem, Child, Child, Preschool, Female, Persons with Disabilities, Humans, Infant, Infant, Newborn, Male, Middle Aged, Skin Diseases, Global Health, Prevalence, Quality-Adjusted Life Years, Young Adult
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