Novel machine learning approach to identify preoperative risk factors associated with super-utilization of medicare expenditure following surgery
Open accessAbstract
Importance: Typically defined as the top 5% of health care users, super-utilizers are responsible for an estimated 40% to 55% of all health care costs. Little is known about which factors may be associated with increased risk of long-term postoperative super-utilization. Objective: To identify clusters of patients with distinct constellations of clinical and comorbid patterns who may be associated with an elevated risk of super-utilization in the year following elective surgery. Design, Setting, and Participants: A retrospective longitudinal cohort study of 1 049 160 patients who underwent abdominal aortic aneurysm repair, coronary artery bypass graft, colectomy, total hip arthroplasty, total knee arthroplasty, or lung resection were identified from the 100% Medicare inpatient and outpatient Standard Analytic Files at all inpatient facilities performing 1 or more of the evaluated surgical procedures from 2013 to 2015. Data from 2012 to 2016 were used to evaluate expenditures in the year preceding and following surgery. Using a machine learning approach known as Logic Forest, comorbidities and interactions of comorbidities that put patients at an increased chance of becoming a super-utilizer were identified. All comorbidities, as defined by the Charlson (range, 0-24) and Elixhauser (range, 0-29) comorbidity indices, were used in the analysis. Higher scores indicated higher comorbidity burden. Data analysis was completed on November 16, 2018. Main Outcome and Measures: Super-utilization of health care in the year following surgery. Results: In total, 1 049 160 patients met inclusion criteria and were included in the analytic cohort. Their median (interquartile range) age was 73 (69-78) years, and approximately 40% were male. Super-utilizers comprised 4.8% of the overall cohort (n = 79 746) yet incurred 31.7% of the expenditures. Although the difference in overall expenditures per person between super-utilizers ($4049) and low users ($2148) was relatively modest prior to surgery, the difference in expenditures between super-utilizers ($79 698) vs low users ($2977) was marked in the year following surgery. Risk factors associated with super-utilization of health care included hemiplegia/paraplegia (odds ratio, 5.2; 95% CI, 4.4-6.2), weight loss (odds ratio, 3.5; 95% CI, 2.9-4.2), and congestive heart failure with chronic kidney disease stages I to IV (odds ratio, 3.4; 95% CI, 3.0-3.9). Conclusions and Relevance: Super-utilizers comprised only a small fraction of the surgical population yet were responsible for a disproportionate amount of Medicare expenditure. Certain subpopulations were associated with super-utilization of health care following surgical intervention despite having lower overall use in the preoperative period.
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Other ML models have been developed and validated to predict the risk of super-utilization and plan accordingly, starting in the preoperative setting.
“Other ML models have also been developed and validated to predict the risk of super-utilization and plan accordingly, starting in the preoperative setting in an increased effort to enhance value-based care (17).”
From Accessing Artificial Intelligence for Clinical Decision-Making (2021) · cites this paper as [17]
A growing nationwide effort is seeking to enhance preoperative and perioperative support for high-risk patients and high-cost populations.
“A growing nationwide effort is seeking to enhance preoperative and perioperative support for high-risk patients and high-cost populations (16, 17).”
From Accessing Artificial Intelligence for Clinical Decision-Making (2021) · cites this paper as [17]
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Fight for the People's Health: The Application of Al Multiagent Systems in Medical Consortia
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- Authors
- Hyer, J. M., Ejaz, A., Tsilimigras, D. I., Paredes, A. Z., Mehta, R., & Pawlik, T. M.
- Affiliations
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- Corresponding author
- Pawlik, Timothy M.
- ORCID
- Venue
- JAMA Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 2019-11-01
- Volume
- 154
- Issue
- 11
- Pages
- 1014
- ISSN
- 2168-6254 (ISSN-L)
- PMC
- PMC6694398
- OpenAlex
- W2967100253
- Cited by
- 49
- References
- 51
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 6 · 2023: 5 · 2022: 10 · 2021: 7 · 2020: 8 · 2019: 3
- FWCI
- 5.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Surgery (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Healthcare Policy and Management
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Keywords
- Medicare spending, postoperative care, comorbidities, comorbidity burden, patient clustering, elective surgery, abdominal aortic aneurysm repair, coronary artery bypass grafting, colectomy, total hip arthroplasty, total knee arthroplasty, lung resection, health care costs, risk factors, Charlson Comorbidity Index
- MeSH terms
- Machine Learning, Aged, Health Expenditures, Female, Medicare, Humans, Male, Patient Acceptance of Health Care, Postoperative Care, Preoperative Care, Retrospective Studies, Risk Factors, United States, Elective Surgical Procedures, Risk Assessment
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