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The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Dextran Sulfate Sodium (DSS)‐Induced Colitis in Mice

Open access
Chassaing, Benoit, Aitken, Jesse D., Malleshappa, Madhu, Vijay‐Kumar, Matam·2014·Current Protocols in Immunology

Abstract

Inflammatory bowel diseases (IBD), mainly comprising ulcerative colitis and Crohn's Disease, are complex and multifactorial diseases with unknown etiology. For the past 20 years, to study human IBD mechanistically, a number of murine models of colitis have been developed. These models are indispensable tools to decipher underlying mechanisms of IBD pathogenesis as well as to evaluate a number of potential therapeutics. Among various chemically induced colitis models, the dextran sulfate sodium (DSS)‐induced colitis model is widely used because of its simplicity and many similarities with human ulcerative colitis. This model has both advantages and disadvantages that must be considered when employed. This protocol describes the DSS‐induced colitis model, focusing on details and factors that could affect DSS‐induced pathology. Curr. Protoc. Immunol. 104:15.25.1‐15.25.14. © 2014 by John Wiley & Sons, Inc.

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Metadata

Authors
Chassaing, B., Aitken, J. D., Malleshappa, M., & Vijay‐Kumar, M.
Venue
Current Protocols in Immunology
Publisher
Wiley
Published
2014-02
Volume
104
Issue
1
Pages
15.25.1-15.25.14
ISSN
  • 1934-3671 (ISSN-L)
  • 1934-368X
OpenAlex
W1596258860
Cited by
2,090
References
6
FWCI
32.10
Type
journal article
Language
en
Open access
green

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.