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Nicotine replacement therapy for smoking cessation

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Stead, Lindsay F, Perera, Rafael, Bullen, Chris, Mant, David, Hartmann-Boyce, Jamie, Cahill, Kate, Lancaster, Tim·2012·Cochrane Database of Systematic Reviews
DOI 10.1002/14651858.cd000146.pub4
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Abstract

BACKGROUND: The aim of nicotine replacement therapy (NRT) is to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence. OBJECTIVES: The aims of this review were: To determine the effect of NRT compared to placebo in aiding smoking cessation, and to consider whether there is a difference in effect for the different forms of NRT (chewing gum, transdermal patches, oral and nasal sprays, inhalers and tablets/lozenges) in achieving abstinence from cigarettes. To determine whether the effect is influenced by the dosage, form and timing of use of NRT; the intensity of additional advice and support offered to the smoker; or the clinical setting in which the smoker is recruited and treated. To determine whether combinations of NRT are more likely to lead to successful quitting than one type alone. To determine whether NRT is more or less likely to lead to successful quitting compared to other pharmacotherapies. SEARCH METHODS: We searched the Cochrane Tobacco Addiction Group trials register for papers mentioning 'NRT' or any type of nicotine replacement therapy in the title, abstract or keywords. Date of most recent search July 2012. SELECTION CRITERIA: Randomized trials in which NRT was compared to placebo or to no treatment, or where different doses of NRT were compared. We excluded trials which did not report cessation rates, and those with follow-up of less than six months. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the type of participants, the dose, duration and form of nicotine therapy, the outcome measures, method of randomization, and completeness of follow-up. The main outcome measure was abstinence from smoking after at least six months of follow-up. We used the most rigorous definition of abstinence for each trial, and biochemically validated rates if available. We calculated the risk ratio (RR) for each study. Where appropriate, we performed meta-analysis using a Mantel-Haenszel fixed-effect model. MAIN RESULTS: We identified 150 trials; 117 with over 50,000 participants contributed to the primary comparison between any type of NRT and a placebo or non-NRT control group. The risk ratio (RR) of abstinence for any form of NRT relative to control was 1.60 (95% confidence interval [CI] 1.53 to 1.68). The pooled RRs for each type were 1.49 (95% CI 1.40 to 1.60, 55 trials) for nicotine gum; 1.64 (95% CI 1.52 to 1.78, 43 trials) for nicotine patch; 1.95 (95% CI 1.61 to 2.36, 6 trials) for oral tablets/lozenges; 1.90 (95% CI 1.36 to 2.67, 4 trials) for nicotine inhaler; and 2.02 (95% CI 1.49 to 2.73, 4 trials) for nicotine nasal spray. One trial of oral spray had an RR of 2.48 (95% CI 1.24 to 4.94). The effects were largely independent of the duration of therapy, the intensity of additional support provided or the setting in which the NRT was offered. The effect was similar in a small group of studies that aimed to assess use of NRT obtained without a prescription. In highly dependent smokers there was a significant benefit of 4 mg gum compared with 2 mg gum, but weaker evidence of a benefit from higher doses of patch. There was evidence that combining a nicotine patch with a rapid delivery form of NRT was more effective than a single type of NRT (RR 1.34, 95% CI 1.18 to 1.51, 9 trials). The RR for NRT used for a short period prior to the quit date was 1.18 (95% CI 0.98 to 1.40, 8 trials), just missing statistical significance, though the efficacy increased when we pooled only patch trials and when we removed one trial in which confounding was likely. Five studies directly compared NRT to a non-nicotine pharmacotherapy, bupropion; there was no evidence of a difference in efficacy (RR 1.01; 95% CI 0.87 to 1.18). A combination of NRT and bupropion was more effective than bupropion alone (RR 1.24; 95% CI 1.06 to 1.45, 4 trials). Adverse effects from using NRT are related to the type of product, and include skin irritation from patches and irritation to the inside of the mouth from gum and tablets. There is no evidence that NRT increases the risk of heart attacks. AUTHORS' CONCLUSIONS: All of the commercially available forms of NRT (gum, transdermal patch, nasal spray, inhaler and sublingual tablets/lozenges) can help people who make a quit attempt to increase their chances of successfully stopping smoking. NRTs increase the rate of quitting by 50 to 70%, regardless of setting. The effectiveness of NRT appears to be largely independent of the intensity of additional support provided to the individual. Provision of more intense levels of support, although beneficial in facilitating the likelihood of quitting, is not essential to the success of NRT.

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Research works printed but not linked: 440

  1. Abelin, 1989, Controlled trial of transdermal nicotine patch in tobacco withdrawal, Lancet, 1, 7, 10.1016/S0140-6736(89)91671-1 · DOI
  2. Abelin, 1989, Effectiveness of a transdermal nicotine system in smoking cessation studies, Methods and Findings in Experimental and Clinical Pharmacology, 11, 205
  3. Muller, 1990, The use of transdermal nicotine in smoking cessation, Lung, 168, 445, 10.1007/BF02718163 · DOI
  4. Ahluwalia, 1998, Smoking cessation among inner-city African Americans using the nicotine transdermal patch, Journal of General Internal Medicine, 13, 1, 10.1046/j.1525-1497.1998.00001.x · DOI
  5. Ahluwalia, 2006, The effects of nicotine gum and counseling among African American light smokers: A 2 x 2 factorial design, Addiction, 101, 883, 10.1111/j.1360-0443.2006.01461.x · DOI
  6. Berg, 2010, Predictors of smoking reduction among Blacks, Nicotine & Tobacco Research, 12, 423, 10.1093/ntr/ntq019 · DOI
  7. Nollen, 2006, Predictors of quitting among African American light smokers enrolled in a randomized, placebo-controlled trial, Journal of General Internal Medicine, 21, 590, 10.1111/j.1525-1497.2006.00404.x · DOI
  8. Okuyemi, 2007, Baseline characteristics and recruitment strategies in a randomized clinical trial of African-American light smokers, American Journal of Health Promotion, 21, 183, 10.4278/0890-1171-21.3.183 · DOI
  9. Okuyemi, 2007, Relationship between menthol cigarettes and smoking cessation among African American light smokers, Addiction, 102, 1979, 10.1111/j.1360-0443.2007.02010.x · DOI
  10. Okuyemi, 2007, Nicotine dependence among African American light smokers: a comparison of three scales, Addictive Behaviors, 32, 1989, 10.1016/j.addbeh.2007.01.002 · DOI
  11. Okuyemi, 2010, Relationship between smoking reduction and cessation among light smokers, Nicotine & Tobacco Research, 12, 1005, 10.1093/ntr/ntq138 · DOI
  12. Okuyemi, 2010, Predictors of adherence to nicotine gum and counseling among African-American light smokers, Journal of General Internal Medicine, 25, 969, 10.1007/s11606-010-1386-x · DOI
  13. Thomas, 2009, Psychometric properties of a Brief Smoking Consequences Questionnaire for Adults (SCQ-A) among African American light smokers, Substance Abuse, 30, 14, 10.1080/08897070802606345 · DOI
  14. Warren, 2010, Predicting home smoking restrictions among African American light smokers, American Journal of Health Behavior, 34, 110, 10.5993/AJHB.34.1.13 · DOI
  15. Warren, 2010, Development and validation of a multidimensional measure of stress among African American light smokers, Journal of the National Medical Association, 102, 890, 10.1016/S0027-9684(15)30707-0 · DOI
  16. Areechon, 1988, Smoking cessation through the use of nicotine chewing gum: a double-blind trial in Thailand, Clinical Therapeutics, 10, 183
  17. Blondal, 1989, Controlled trial of nicotine polacrilex gum with supportive measures, Archives of Internal Medicine, 149, 1818, 10.1001/archinte.1989.00390080080018 · DOI
  18. Blondal, 1997, A double-blind randomized trial of nicotine nasal spray as an aid in smoking cessation, European Respiratory Journal, 10, 1585, 10.1183/09031936.97.10071585 · DOI
  19. Blondal, 1993, Controlled trial of nicotine nasal spray as an aid to stopping smoking [abstract], European Respiratory Journal, 6, 631S
  20. Blondal, 1999, Nicotine nasal spray with nicotine patch for smoking cessation: randomised trial with six year follow up, BMJ, 318, 285, 10.1136/bmj.318.7179.285 · DOI · Paper page
  21. Blondal T Ludviksdottir D Gudmundsson L Olafsdottir I Gustavsson G Westin A Efficacy of nicotine nasal spray added to transdermal nicotine patches in smoking cessation [Abstract] Proceedings of the 10th World Conference on Tobacco or Health; Aug 24-28; Beijing, China 1997 48
  22. Bohadana, 2003, Gender differences in quit rates following smoking cessation with combination nicotine therapy: influence of baseline smoking behavior, Nicotine & Tobacco Research, 5, 111, 10.1080/1462220021000060482 · DOI · Paper page
  23. Bohadana, 2000, Nicotine inhaler and nicotine patch as a combination therapy for smoking cessation - A randomized, double-blind, placebo-controlled trial, Archives of Internal Medicine, 160, 3128, 10.1001/archinte.160.20.3128 · DOI
  24. Bohandana, 1999, Nicotine inhaler and nicotine patch: a combination therapy for smoking cessation [abstract], Nicotine & Tobacco Research, 1, 189
  25. Bolin, 1999, Transdermal nicotine: the long and the short of it, Psychology of Addictive Behaviors, 13, 152, 10.1037/0893-164X.13.2.152 · DOI
  26. Bolliger, 2000, Practical experiences in smoking reduction and cessation, Addiction, 95, S19, 10.1046/j.1360-0443.95.1s1.2.x · DOI
  27. Bolliger, 2002, Influence of long-term smoking reduction on health risk markers and quality of life, Nicotine & Tobacco Research, 4, 433, 10.1080/1462220021000018380 · DOI
  28. Bolliger, 2000, Smoking reduction with oral nicotine inhalers: double blind, randomised clinical trial of efficacy and safety, BMJ, 321, 329, 10.1136/bmj.321.7257.329 · DOI · Paper page
  29. Brantmark, 1973, Nicotine-containing chewing gum as an anti-smoking aid, Psychopharmacologia, 31, 191, 10.1007/BF00422509 · DOI
  30. Research Committee of the British Thoracic Society, 1983, Comparison of four methods of smoking withdrawal in patients with smoking related diseases. Report by a subcommittee of the Research Committee of the British Thoracic Society, British Medical Journal, 286, 595, 10.1136/bmj.286.6365.595 · DOI
  31. Buchkremer, 1989, Combination of behavioral smoking cessation with transdermal nicotine substitution, Addictive Behaviors, 14, 229, 10.1016/0306-4603(89)90054-3 · DOI
  32. Buchkremer, 1988, Long-term effects of a combination of transdermal nicotine administration with behavior therapy for smoking cessation, Nervenarzt, 59, 488
  33. Bullen, 2010, Pre-cessation nicotine replacement therapy: pragmatic randomized trial, Addiction, 105, 1474, 10.1111/j.1360-0443.2010.02989.x · DOI
  34. Campbell, 1987, Do nicotine chewing-gum and postal encouragement add to doctors' advice, Practitioner, 231, 114
  35. Campbell, 1991, Smoking cessation in hospital patients given repeated advice plus nicotine or placebo chewing gum, Respiratory Medicine, 85, 155, 10.1016/S0954-6111(06)80295-7 · DOI
  36. Burton S Campbell IA Prescott RJ Nicotine patches versus placebo in 235 hospital patients [abstract 191] Abstracts from the 8th World Conference on Tobacco or Health, Mar 30-Apr 3; Buenos Aires, Argentina 1992
  37. Campbell, 1996, Transdermal nicotine plus support in patients attending hospital with smoking-related diseases: a placebo-controlled study, Respiratory Medicine, 90, 47, 10.1016/S0954-6111(96)90244-9 · DOI
  38. Tonnesen, 1999, Higher dosage nicotine patches increase one-year smoking cessation rates: Results from the European CEASE trial, European Respiratory Journal, 13, 238, 10.1034/j.1399-3003.1999.13b04.x · DOI
  39. Cinciripini, 1996, Behavior therapy and the transdermal nicotine patch: Effects on cessation outcome, affect, and coping, Journal of Consulting and Clinical Psychology, 64, 314, 10.1037/0022-006X.64.2.314 · DOI
  40. Clavel, 1984, Tobacco withdrawal. Comparison of the efficacy of various methods. Intermediate results of a comparative study [French], Presse Médicale, 13, 975
  41. Clavel, 1985, Helping people to stop smoking: randomised comparison of groups being treated with acupuncture and nicotine gum with control group, British Medical Journal, 291, 1538, 10.1136/bmj.291.6508.1538 · DOI
  42. Clavel-Chapelon, 1992, A randomised 2 x 2 factorial design to evaluate different smoking cessation methods, Revue d'Epidemiologie et de Sante Publique, 40, 187
  43. Coleman, 2007, Protocol for the Smoking, Nicotine and Pregnancy (SNAP) trial: Double-blind, placebo-randomised, controlled trial of nicotine replacement therapy in pregnancy, BMC Health Services Research, 7, 2, 10.1186/1472-6963-7-2 · DOI
  44. Thornton, 2011, The smoking, nicotine and pregnancy (SNAP) trial: Main results, Archives of Disease in Childhood: Fetal and Neonatal Edition, 96, Fa109, 10.1136/adc.2011.300163.40 · DOI
  45. Cooney, 2009, Smoking cessation during alcohol treatment: a randomized trial of combination nicotine patch plus nicotine gum, Addiction, 104, 1588, 10.1111/j.1360-0443.2009.02624.x · DOI
  46. Cooper, 2005, A placebo controlled randomized trial of the effects of phenylpropanolamine and nicotine gum on cessation rates and postcessation weight gain in women, Addictive Behaviors, 30, 61, 10.1016/j.addbeh.2004.04.013 · DOI
  47. Croghan, 1998, Comparison of a 15 mg transdermal nicotine patch alone versus nicotine nasal spray alone versus both for smoking cessation, Journal of Addictive Diseases, 17, 121
  48. Croghan, 2003, Comparison of nicotine patch alone versus nicotine nasal sparay alone versus a combination for treating smokers: A minimal intervention, randomized multicenter trial in a nonspecialized setting, Nicotine & Tobacco Research, 5, 181, 10.1080/1462220031000073252 · DOI
  49. Dale, 1995, High-dose nicotine patch therapy - percentage of replacement and smoking cessation, JAMA, 274, 1353, 10.1001/jama.1995.03530170033028 · DOI
  50. Dale, 1998, Weight change after smoking cessation using variable doses of transdermal nicotine replacement, Journal of General Internal Medicine, 13, 9, 10.1046/j.1525-1497.1998.00002.x · DOI
  51. Daughton, 1991, Effect of transdermal nicotine delivery as an adjunct to low-intervention smoking cessation therapy. A randomized, placebo-controlled, double-blind study, Archives of Internal Medicine, 151, 749, 10.1001/archinte.1991.00400040091020 · DOI
  52. Daughton, 1992, Effects of transdermal nicotine as an adjunct in smoking cessation therapy. A double-blind randomized study controlled with placebo [Italian], Archivio Monaldi, 47, 17
  53. Daughton, 1998, Transdermal nicotine therapy and primary care. Importance of counseling, demographic, and participant selection factors on 1-year quit rates. The Nebraska Primary Practice Smoking Cessation Trial Group, Archives of Family Medicine, 7, 425, 10.1001/archfami.7.5.425 · DOI
  54. Dautzenberg B Peiffer G Toulouse F Yvinec MJ Jacob N Kienzler JL Randomized trial assessment of nicotinell lozenge 1mg, a new oral nicotine replacement therapy Abstract Book. Society for Research on Nicotine and Tobacco 3rd European Conference, Paris 2001 55
  55. Dautzenberg, 2001, First demonstration of the good efficacy/safety ratio of Nicotinell® 1mg Lozenge (NL 1mg), a new form of nicotine substitution, by randomised clinical trial, European Respiratory Journal, 18 Suppl 33, 12s
  56. Davidson, 1998, Efficacy and safety of an over-the-counter transdermal nicotine patch as an aid for smoking cessation, Archives of Family Medicine, 7, 569, 10.1001/archfami.7.6.569 · DOI
  57. Abelin, 1991, Clinical experience with a transdermal nicotine system in healthy nicotine-dependent smokers, 35
  58. Abelin, 1989, Effectiveness of a transdermal nicotine system in smoking cessation studies, Methods and Findings in Experimental and Clinical Pharmacology, 11, 205
  59. Ehrsam, 1991, Weaning of young smokers using a transdermal nicotine patch [German], Schweizerische Rundschau fur Medizin Praxis, 80, 145
  60. Muller, 1990, The use of transdermal nicotine in smoking cessation, Lung, 168, 445, 10.1007/BF02718163 · DOI
  61. Etter, 2009, Nicotine gum treatment before smoking cessation: a randomized trial, Archives of Internal Medicine, 169, 1028, 10.1001/archinternmed.2009.12 · DOI
  62. Fagerstrom, 1982, A comparison of psychological and pharmacological treatment in smoking cessation, Journal of Behavioral Medicine, 5, 343, 10.1007/BF00846161 · DOI
  63. Fagerstrom, 1983, Tolerance, withdrawal and dependence on tobacco and smoking termination, International Review of Applied Psychology, 32, 29, 10.1111/j.1464-0597.1983.tb01185.x · DOI
  64. Fagerstrom, 1984, Effects of nicotine chewing gum and follow-up appointments in physician-based smoking cessation, Preventive Medicine, 13, 517, 10.1016/0091-7435(84)90020-3 · DOI
  65. Fee, 1982, A controlled trial of nicotine chewing gum in a smoking withdrawal clinic, Practitioner, 226, 148
  66. Fiore, 1994, Two studies of the clinical effectiveness of the nicotine patch with different counseling treatments, Chest, 105, 524, 10.1378/chest.105.2.524 · DOI
  67. Fiore, 1994, Two studies of the clinical effectiveness of the nicotine patch with different counseling treatments, Chest, 105, 524, 10.1378/chest.105.2.524 · DOI
  68. Fortmann, 1995, Nicotine gum and self-help behavioral treatment for smoking relapse prevention - resuIts from a trial using population-based recruitment, Journal of Consulting and Clinical Psychology, 63, 460, 10.1037/0022-006X.63.3.460 · DOI
  69. Quilez Garcia, 1993, Treatment for smoking with nicotine gum in primary care. A double blind trial [Spanish], Revista Clinica Espanol, 192, 157
  70. Quilez Garcia, 1989, Double-blind study of the efficacy of nicotine chewing gum for smoking cessation in the primary care setting [Spanish], Atencion Primaria, 6, 719
  71. Gariti, 2009, Comparing smoking treatment programs for lighter smokers with and without a history of heavier smoking, Journal of Substance Abuse Treatment, 37, 247, 10.1016/j.jsat.2009.01.006 · DOI
  72. Doherty, 1996, Nicotine gum dose and weight gain after smoking cessation, Journal of Consulting and Clinical Psychology, 64, 799, 10.1037/0022-006X.64.4.799 · DOI
  73. Ferguson, 2011, Effect of compliance with nicotine gum dosing on weight gained during a quit attempt, Addiction, 106, 651, 10.1111/j.1360-0443.2010.03244.x · DOI
  74. Garvey, 2000, Effects of nicotine gum dose by level of nicotine dependence, Nicotine & Tobacco Research, 2, 53, 10.1080/14622200050011303 · DOI
  75. Kinnunen, 1996, Depression and smoking cessation - characteristics of depressed smokers and effects of nicotine replacement, Journal of Consulting and Clinical Psychology, 64, 791, 10.1037/0022-006X.64.4.791 · doi:10.1037/0022-006x.64.4.791
  76. Nordstrom, 1999, Long-term effects of nicotine gum on weight gain after smoking cessation, Nicotine & Tobacco Research, 1, 259, 10.1080/14622299050011381 · DOI
  77. Gilbert, 1989, Smoking cessation in primary care. A randomized controlled trial of nicotine-bearing chewing gum, Journal of Family Practice, 28, 49
  78. Glavas, 2003, Smoking cessation with nicotine replacement therapy among health care workers: randomized double-blind study, Croatian Medical Journal, 44, 219
  79. Glavas, 2003, Smoking cessation using the transdermal nicotine system [Croatian], Lijecnicki Vjesnik, 125, 8
  80. Glover E Glover P Franzon M Sullivan R Cerullo C Safety and efficacy of a nicotine sublingual tablet for smoking cessation [abstract] Smoke Free 21st Century, 2nd European Conference on Tobacco or Health; Las Palmas de Gran Canaria 1999
  81. Glover ED Franzon M Sullivan CR Cerullo CL A nicotine sublingual tablet for treating tobacco dependence [Abstract] Society for Research on Nicotine and Tobacco 3rd Europe Conference, Paris September 2001 Abstract Book 2001 48
  82. Glover, 2002, A comparison of a nicotine sublingual tablet and placebo for smoking cessation, Nicotine & Tobacco Research, 4, 441, 10.1080/1462220021000018443 · DOI
  83. Glover ED Glover PN Franzon M Sullivan R Sullivan P Howell R A nicotine sublingual tablet for smoking cessation: 6-month data [Abstract] Proceedings of the 10th World Conference on Tobacco or Health; Aug 24-28 Beijing, China 1997
  84. Goldstein, 1989, Effects of behavioral skills training and schedule of nicotine gum administration on smoking cessation, American Journal of Psychiatry, 146, 56, 10.1176/ajp.146.1.56 · DOI
  85. Gross, 1995, Dose effects of nicotine gum, Addictive Behaviors, 20, 371, 10.1016/0306-4603(94)00078-D · DOI
  86. Hall, 1985, Nicotine gum and behavioral treatment in smoking cessation, Journal of Consulting and Clinical Psychology, 53, 256, 10.1037/0022-006X.53.2.256 · DOI
  87. Hall, 1987, Nicotine gum and behavioral treatment: a placebo controlled trial, Journal of Consulting and Clinical Psychology, 55, 603, 10.1037/0022-006X.55.4.603 · DOI
  88. Hall, 1996, Mood management and nicotine gum in smoking treatment - a therapeutic contact and placebo-controlled study, Journal of Consulting and Clinical Psychology, 64, 1003, 10.1037/0022-006X.64.5.1003 · doi:10.1037/0022-006x.64.5.1003
  89. Hand, 2002, Controlled trial of three weeks nicotine replacement treatment in hospital patients also given advice and support, Thorax, 57, 715, 10.1136/thorax.57.8.715 · DOI
  90. Harackiewicz, 1988, Nicotine gum and self-help manuals in smoking cessation: an evaluation in a medical context, Addictive Behaviors, 13, 319, 10.1016/0306-4603(88)90038-X · DOI
  91. Hays, 1999, Over-the-counter nicotine patch therapy for smoking cessation: Results from randomized, double-blind, placebo-controlled and open label trials, American Journal of Public Health, 89, 1701, 10.2105/AJPH.89.11.1701 · DOI
  92. Hays, 1997, Over-the-Counter (OTC) transdermal nicotine patch therapy [abstract], Journal of Addictive Diseases, 16, 136
  93. Hays JT Croghan IT Offord KP Hurt RD Schroeder DR Wolter TD Over the counter 22mg nicotine patch therapy for smoking cessation: results from randomized double-blind placebo-controlled and open label trials Abstract Book. Society for Research on Nicotine and Tobacco 5th Annual Meeting, San Diego (CA) 1999 · DOI
  94. Herrera, 1995, Nicotine gum, 2 and 4 mg, for nicotine dependence. A double-blind placebo-controlled trial within a behavior modification support program, Chest, 108, 447, 10.1378/chest.108.2.447 · DOI · Paper page
  95. Hilleman, 1994, Comparison of fixed-dose transdermal nicotine, tapered-dose transdermal nicotine, and buspirone in smoking cessation, Journal of Clinical Pharmacology, 34, 222, 10.1002/j.1552-4604.1994.tb03989.x · DOI
  96. Hjalmarson, 1984, Effect of nicotine chewing gum in smoking cessation. A randomized, placebo-controlled, double-blind study, JAMA, 252, 2835, 10.1001/jama.1984.03350200021014 · DOI
  97. Hjalmarson, 1994, Effect of nicotine nasal spray on smoking cessation. A randomized, placebo-controlled, double-blind study, Archives of Internal Medicine, 154, 2567, 10.1001/archinte.1994.00420220059007 · DOI
  98. Hjalmarson, 1997, The nicotine inhaler in smoking cessation, Archives of Internal Medicine, 157, 1721, 10.1001/archinte.1997.00440360143016 · DOI
  99. Huber, 1988, Combined and separate treatment effects of nicotine chewing gum and self-control method, Pharmacopsychiatry, 21, 461, 10.1055/s-2007-1017054 · DOI
  100. Hughes, 1991, Long-term use of nicotine vs placebo gum, Archives of Internal Medicine, 151, 1993, 10.1001/archinte.1991.00400100073012 · DOI
  101. Hughes, 1989, Nicotine vs placebo gum in general medical practice, JAMA, 261, 1300, 10.1001/jama.1989.03420090064032 · DOI
  102. Hughes, 1990, Effect of dose on nicotine's reinforcing, withdrawal-suppression and self-reported effects, Journal of Pharmacology and Experimental Therapeutics, 252, 1175, 10.1016/S0022-3565(25)20177-X · DOI
  103. Hughes, 1991, Effect of cost on the self-administration and efficacy of nicotine gum: a preliminary study, Preventive Medicine, 20, 486, 10.1016/0091-7435(91)90046-7 · DOI
  104. Hughes, 1999, Are higher doses of nicotine replacement more effective for smoking cessation?, Nicotine & Tobacco Research, 1, 169, 10.1080/14622299050011281 · DOI
  105. Hughes, 2003, Efficacy of nicotine patch in smokers with a history of alcoholism, Alcoholism-Clinical and Experimental Research, 27, 946, 10.1111/j.1530-0277.2003.tb04419.x · DOI
  106. Hughes, 2010, A randomized, controlled trial of NRT-aided gradual vs. abrupt cessation in smokers actively trying to quit, Drug & Alcohol Dependence, 111, 105, 10.1016/j.drugalcdep.2010.04.007 · DOI
  107. Hurt, 1994, Nicotine patch therapy for smoking cessation combined with physician advice and nurse follow-up: One-year outcome and percentage of nicotine replacement, JAMA, 271, 595, 10.1001/jama.1994.03510320035026 · DOI · Paper page
  108. David, 2007, The serotonin transporter 5-HTTLPR polymorphism and treatment response to nicotine patch: follow-up of a randomized controlled trial, Nicotine & Tobacco Research, 9, 225, 10.1080/14622200601078566 · DOI
  109. Imperial Cancer Research Fund General Practice Research Group, 1993, Effectiveness of a nicotine patch in helping people stop smoking: results of a randomised trial in general practice., BMJ, 306, 1304, 10.1136/bmj.306.6888.1304 · DOI
  110. Imperial Cancer Research Fund General Practice research Group, 1994, Randomised trial of nicotine patches in general practice: results at one year., BMJ, 308, 1476, 10.1136/bmj.308.6942.1476 · DOI
  111. Johnstone, 2004, Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch, Pharmacogenetics, 14, 83, 10.1097/00008571-200402000-00002 · DOI
  112. Yudkin, 2003, Abstinence from smoking eight years after participation in randomised controlled trial of nicotine patch, BMJ, 327, 28, 10.1136/bmj.327.7405.28 · DOI
  113. Yudkin, 2004, Effectiveness of nicotine patches in relation to genotype in women versus men: randomised controlled trial, BMJ, 328, 989, 10.1136/bmj.38050.674826.AE · DOI
  114. Jamrozik, 1984, Placebo controlled trial of nicotine chewing gum in general practice, British Medical Journal, 289, 794, 10.1136/bmj.289.6448.794 · DOI
  115. Jarvis, 1982, Randomised controlled trial of nicotine chewing-gum, British Medical Journal, 285, 537, 10.1136/bmj.285.6341.537 · DOI · Paper page
  116. Jensen, 1990, Effect of nicotine, silver acetate, and ordinary chewing gum in combination with group counselling on smoking cessation, Thorax, 45, 831, 10.1136/thx.45.11.831 · DOI
  117. Jensen, 1991, Effect on smoking cessation of silver acetate, nicotine and ordinary chewing gum. Influence of smoking history, Psychopharmacology (Berl), 104, 470, 10.1007/BF02245651 · DOI
  118. Jensen, 1991, The effect of nicotine, silver acetate, and placebo chewing gum on the cessation of smoking. The influence of smoking type and nicotine dependence, International Journal of the Addictions, 26, 1223, 10.3109/10826089109062156 · DOI
  119. Jorenby, 1995, Varying nicotine patch dose and type of smoking cessation counseling, JAMA, 274, 1347, 10.1001/jama.1995.03530170027027 · DOI · Paper page
  120. Durcan, 2002, Impact of prior nicotine replacement therapy on smoking cessation efficacy, American Journal of Health Behaviors, 26, 213, 10.5993/AJHB.26.3.6 · DOI
  121. Jamerson, 2001, Late-term smoking cessation despite initial failure: an evaluation of bupropion sustained release, nicotine patch, combination therapy, and placebo, Clinical Therapeutics, 23, 744, 10.1016/S0149-2918(01)80023-0 · DOI
  122. Joseph, 1999, Lack of efficacy of transdermal nicotine in smoking cessation, New England Journal of Medicine, 341, 1157, 10.1056/NEJM199910073411514 · DOI
  123. Kalman, 2006, High-dose nicotine patch therapy for smokers with a history of alcohol dependence: 36-week outcomes, Journal of Substance Abuse Treatment, 30, 213, 10.1016/j.jsat.2006.01.001 · DOI
  124. Kalman, 2004, Twelve-week outcomes from an investigation of high-dose nicotine patch therapy for heavy smokers with a past history of alcohol dependence, Psychology of Addictive Behaviors, 18, 78, 10.1037/0893-164X.18.1.78 · DOI
  125. Kalman, 2002, An investigation of predictors of nicotine abstinence in a smoking cessation treatment study of smokers with a past history of alcohol dependence, Psychology of Addictive Behaviors, 16, 346, 10.1037/0893-164X.16.4.346 · DOI
  126. Killen, 1984, Nicotine gum and self-regulation training in smoking relapse prevention, Behavior Therapy, 15, 234, 10.1016/S0005-7894(84)80026-X · DOI
  127. Fortmann, 1988, Minimal contact treatment for smoking cessation. A placebo controlled trial of nicotine polacrilex and self-directed relapse prevention: initial results of the Stanford Stop Smoking Project, JAMA, 260, 1575, 10.1001/jama.1988.03410110083032 · DOI
  128. Killen, 1990, Evaluation of a treatment approach combining nicotine gum with self-guided behavioral treatments for smoking relapse prevention, Journal of Consulting and Clinical Psychology, 58, 85, 10.1037/0022-006X.58.1.85 · DOI
  129. Bailey, 2010, Perceived drug assignment and treatment outcome in smokers given nicotine patch therapy, Journal of Substance Abuse Treatment, 32, 150, 10.1016/j.jsat.2010.05.013 · DOI
  130. Killen, 1997, Nicotine patch and self-help video for cigarette smoking cessation, Journal of Consulting and Clinical Psychology, 65, 663, 10.1037/0022-006X.65.4.663 · DOI
  131. Killen, 1999, Do heavy smokers benefit from higher dose nicotine patch therapy?, Experimental and Clinical Psychopharmacology, 7, 226, 10.1037/1064-1297.7.3.226 · DOI
  132. Kornitzer, 1987, A double blind study of 2 mg versus 4 mg nicotine-gum in an industrial setting, Journal of Psychosomatic Research, 31, 171, 10.1016/0022-3999(87)90073-0 · DOI
  133. Kornitzer, 1995, Combined use of nicotine patch and gum in smoking cessation: a placebo-controlled clinical trial, Preventive Medicine, 24, 41, 10.1006/pmed.1995.1006 · DOI · Paper page
  134. Kornitzer, 1993, Efficiency and safety of combined use of nicotine patches and nicotine gum in smoking cessation: a placebo controlled double-blind trial [abstract], European Respiratory Journal, 6, 630S
  135. Kralikova, 2002, The clinical benefits of NRT-supported smoking reduction, Nicotine & Tobacco Research, 4, 243
  136. Kralikova, 2009, Smoking cessation or reduction with nicotine replacement therapy: a placebo-controlled double blind trial with nicotine gum and inhaler, BMC Public Health, 9, 433, 10.1186/1471-2458-9-433 · DOI
  137. Leischow, 1996, Efficacy of the nicotine inhaler as an adjunct to smoking cessation, American Journal of Health Behavior, 20, 364
  138. Leischow, 1999, OTC nicotine patch: effectiveness alone and with brief physician intervention, American Journal of Health Behavior, 23, 61, 10.5993/AJHB.23.1.7 · DOI
  139. Leischow, 2004, Effectiveness of the nicotine inhaler for smoking cessation in an OTC setting, American Journal of Health Behavior, 28, 291, 10.5993/AJHB.28.4.1 · DOI
  140. Leischow SJ Ranger-Moore J Muramoto ML Matthews E The safety and effectiveness of the nicotine inhaler for smoking cessation in an over-the-counter setting (POS4-78) Abstract Book. Society for Research on Nicotine and Tobacco 9th Annual Meeting, New Orleans, LA 2003 100 · DOI
  141. Lerman, 2006, Role of functional genetic variation in the dopamine D2 receptor (DRD2) in response to bupropion and nicotine replacement therapy for tobacco dependence: results of two randomized clinical trials, Neuropsychopharmacology, 31, 231, 10.1038/sj.npp.1300861 · DOI · Paper page
  142. Lerman, 2006, Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation, Clinical Pharmacology & Therapeutics, 79, 600, 10.1016/j.clpt.2006.02.006 · DOI · Paper page
  143. Lerman, 2004, The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial, Pharmacogenomics Journal, 4, 184, 10.1038/sj.tpj.6500238 · DOI · Paper page
  144. Malaiyandi, 2006, Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy, Molecular Psychiatry, 11, 400, 10.1038/sj.mp.4001794 · DOI · Paper page
  145. Patterson, 2003, Predictors of attendance in a randomized clinical trial of nicotine replacement therapy with behavioral counseling, Drug and Alcohol Dependence, 72, 123, 10.1016/S0376-8716(03)00194-7 · DOI
  146. Lewis, 1998, Transdermal nicotine replacement for hospitalized patients: A randomized clinical trial, Preventive Medicine, 27, 296, 10.1006/pmed.1998.0266 · DOI
  147. Salvador Llivina, 1988, Treatment of smoking: efficacy of the use of nicotine chewing gum. Double-blind study [Spanish], Medicina Clinica Barcelona, 90, 646
  148. Malcolm, 1980, The use of nicotine chewing gum as an aid to stopping smoking, Psychopharmacology Series, 70, 295, 10.1007/BF00427889 · DOI
  149. Marshall, 1985, Nicotine chewing gum in general practice: effect of follow up appointments, British Medical Journal, 290, 1397, 10.1136/bmj.290.6479.1397 · DOI
  150. McGovern, 1992, An assessment of nicotine gum as an adjunct to Freedom from Smoking cessation clinics, Addictive Behaviors, 17, 137, 10.1016/0306-4603(92)90018-Q · DOI
  151. Molyneux, 2003, Clinical trial comparing nicotine replacement therapy (NRT) plus brief counselling, brief counselling alone, and minimal intervention on smoking cessation in hospital inpatients, Thorax, 58, 484, 10.1136/thorax.58.6.484 · DOI
  152. Collins, 2010, Puffing behavior during the smoking of a single cigarette in tobacco-dependent adolescents, Nicotine & Tobacco Research, 12, 164, 10.1093/ntr/ntp176 · DOI
  153. Franken, 2006, Smoking rates and topography predict adolescent smoking cessation following treatment with nicotine replacement therapy, Cancer Epidemiology, Biomarkers & Prevention, 15, 154, 10.1158/1055-9965.EPI-05-0167 · DOI
  154. Jaszyna-Gasior, 2009, Age at menarche and weight concerns in relation to smoking trajectory and dependence among adolescent girls enrolled in a smoking cessation trial, Addictive Behaviors, 34, 92, 10.1016/j.addbeh.2008.08.001 · DOI
  155. Moolchan, 2005, Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addiction, Pediatrics, 115, e407, 10.1542/peds.2004-1894 · DOI · Paper page
  156. Robinson, 2006, Adolescent smokers screened for a nicotine replacement treatment trial: Correlates of eligibility and enrollment, Nicotine & Tobacco Research, 8, 447, 10.1080/14622200600670413 · DOI
  157. Thorner-Bantug, 2009, Weight gain, related concerns, and treatment outcomes among adolescent smokers enrolled in cessation treatment, Journal of the National Medical Association, 101, 1009, 10.1016/S0027-9684(15)31067-1 · DOI
  158. Mori T Shimao T Yulchiro G Namiki M Hyachi T A clinical trial of nicotine chewing gum for smoking cessation [abstract 428] 8th World Conference on Tobacco or Health; Buenos Aires, Argentina 1992
  159. Nakamura M Saito J Oshima A Miyamoto M Matushita A Endo S Effect of nicotine chewing gun in smoking cessation classes The Global War. Proceedings of the 7th World Conference on Tobacco and Health; Perth, Western Australia Perth Health Department of Western Australia 1990 665 7
  160. Nebot, 1992, Does nurse counseling or offer of nicotine gum improve the effectiveness of physician smoking-cessation advice?, Family Practice Research Journal, 12, 263
  161. Niaura, 1994, Matching high and low-dependence smokers to self-help treatment with or without nicotine replacement, Preventive Medicine, 23, 70, 10.1006/pmed.1994.1010 · DOI
  162. Niaura, 1999, Cue exposure treatment for smoking relapse prevention: A controlled clinical trial, Addiction, 94, 685, 10.1046/j.1360-0443.1999.9456856.x · DOI
  163. Ockene, 1994, The physician-delivered smoking intervention project: can short-term interventions produce long-term effects for a general outpatient population?, Health Psychology, 13, 278, 10.1037/0278-6133.13.3.278 · DOI · Paper page
  164. Kleppinger, 2010, Effects of smoking cessation on body composition in postmenopausal women, Journal of Women's Health, 19, 1651, 10.1089/jwh.2009.1853 · DOI
  165. Oncken, 2007, Transdermal nicotine for smoking cessation in postmenopausal women, Addictive Behaviors, 32, 296, 10.1016/j.addbeh.2006.04.004 · DOI
  166. Fish, 2009, Adherence to nicotine replacement therapy among pregnant smokers, Nicotine & Tobacco Research, 11, 514, 10.1093/ntr/ntp032 · DOI
  167. Swamy, 2009, Predictors of adverse events among pregnant smokers exposed in a nicotine replacement therapy trial, American Journal of Obstetrics & Gynecology, 201, 354, 10.1016/j.ajog.2009.06.006 · DOI
  168. Ortega, 2011, Effectiveness of a cognitive orientation program with and without nicotine replacement therapy in stopping smoking in hospitalised patients, Archivos de Bronconeumologia, 47, 3, 10.1016/S1579-2129(11)70002-7 · DOI
  169. Otero, 2006, Randomized clinical trial: effectiveness of the cognitive-behavioral approach and the use of nicotine replacement transdermal patches for smoking cessation among adults in Rio de Janeiro, Brazil [Portugese], Cadernos de Saude Publica, 22, 439, 10.1590/S0102-311X2006000200021 · DOI
  170. Page, 1986, Smoking cessation in family practice: the effects of advice and nicotine chewing gum prescription, Addictive Behaviors, 11, 443, 10.1016/0306-4603(86)90025-0 · DOI
  171. Cosci, 2009, Nicotine dependence, psychological distress and personality traits as possible predictors of smoking cessation. Results of a double-blind study with nicotine patch, Addictive Behaviors, 34, 28, 10.1016/j.addbeh.2008.08.003 · DOI
  172. Fornai, 2001, Smoking reduction in smokers compliant to a smoking cessation trial with nicotine patch, Monaldi Archives for Chest Disease, 56, 5
  173. Paoletti, 1996, Importance of baseline cotinine plasma values in smoking cessation: results from a double blind study with nicotine patch, European Respiratory Journal, 9, 643, 10.1183/09031936.96.09040643 · DOI
  174. Perng, 1999, Randomized, double-blind, placebo-controlled study of transdermal nicotine patch for smoking cessation, American Journal of Respiratory and Critical Care Medicine, 159, A735
  175. Perng, 1998, Randomized, double-blind, placebo-controlled study of transdermal nicotine patch for smoking cessation, Journal of the Formosan Medical Association, 97, 547
  176. Piper, 2007, Efficacy of bupropion alone and in combination with nicotine gum, Nicotine & Tobacco Research, 9, 947, 10.1080/14622200701540820 · DOI
  177. Asthana, 2010, Effects of smoking intensity and cessation on inflammatory markers in a large cohort of active smokers, American Heart Journal, 160, 458, 10.1016/j.ahj.2010.06.006 · DOI
  178. Gepner, 2011, Effects of smoking and smoking cessation on lipids and lipoproteins: outcomes from a randomized clinical trial, American Heart Journal, 161, 145, 10.1016/j.ahj.2010.09.023 · DOI · Paper page
  179. Japuntich, 2011, The effect of five smoking cessation pharmacotherapies on smoking cessation milestones, Journal of Consulting & Clinical Psychology, 79, 34, 10.1037/a0022154 · DOI
  180. Johnson, 2010, Effects of smoking and smoking cessation on endothelial function: 1-year outcomes from a randomized clinical trial, Journal of the American College of Cardiology, 55, 1988, 10.1016/j.jacc.2010.03.002 · DOI · Paper page
  181. Piper, 2009, A randomized placebo-controlled clinical trial of 5 smoking cessation pharmacotherapies, Archives of General Psychiatry, 66, 1253, 10.1001/archgenpsychiatry.2009.142 · DOI
  182. Pirie, 1992, Smoking cessation in women concerned about weight, American Journal of Public Health, 82, 1238, 10.2105/AJPH.82.9.1238 · DOI · Paper page
  183. Pollak, 2007, Nicotine replacement and behavioral therapy for smoking cessation in pregnancy, American Journal of Preventive Medicine, 33, 297, 10.1016/j.amepre.2007.05.006 · DOI · Paper page
  184. Prapavessis, 2007, The effects of exercise and nicotine replacement therapy on smoking rates in women, Addictive Behaviors, 32, 1416, 10.1016/j.addbeh.2006.10.005 · DOI
  185. Puska, 1979, Nicotine-containing chewing gum in smoking cessation: a double blind trial with half year follow-up, Addictive Behaviors, 4, 141, 10.1016/0306-4603(79)90048-0 · DOI
  186. Puska, 1995, Combined use of nicotine patch and gum compared with gum alone in smoking cessation: a clinical trial in North Karelia, Tobacco Control, 4, 231, 10.1136/tc.4.3.231 · DOI
  187. Richmond, 1990, General Practitioner interventions for smoking cessation: past results and future prospects, Behaviour Change, 7, 110, 10.1017/S0813483900007087 · DOI
  188. Richmond RL Makinson RJ Giugni AA Webster IW General Practitioner smoking interventions in Australia: results of studies over the past ten years The Global War, Proceedings of the 7th World Conference on Tobacco and Health. Perth, Western Australia Perth Health Department of Western Australia 1990 657 60
  189. Richmond, 1993, One-year evaluation of three smoking cessation interventions administered by general practitioners, Addictive Behaviors, 18, 187, 10.1016/0306-4603(93)90049-F · DOI
  190. Richmond, 1994, The transdermal nicotine patch: results of a randomised placebo-controlled trial, Medical Journal of Australia, 161, 130, 10.5694/j.1326-5377.1994.tb127344.x · DOI
  191. Richmond, 1997, Effectiveness of a 24-hour transdermal nicotine patch in conjunction with a cognitive behavioural programme: One year outcome, Addiction, 92, 27
  192. Rose, 1994, Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone, Clinical Pharmacology and Therapeutics, 56, 86, 10.1038/clpt.1994.105 · DOI
  193. Rose, 1996, Nicotine/mecamylamine combination treatment for smoking cessation [published erratum appears in Drug Development Research 1997;40:215], Drug Development Research, 38, 243, 10.1002/(SICI)1098-2299(199607/08)38:3/4<243::AID-DDR13>3.0.CO;2-# · DOI
  194. Rose, 1998, Nicotine-mecamylamine treatment for smoking cessation: the role of pre-cessation therapy, Experimental and Clinical Psychopharmacology, 6, 331, 10.1037/1064-1297.6.3.331 · doi:10.1037/1064-1297.6.3.331 · Paper page
  195. Rose, 1996, Nicotine/mecamylamine combination treatment for smoking cessation [published erratum appears in Drug Development Research 1997;40:215], Drug Development Research, 38, 243, 10.1002/(SICI)1098-2299(199607/08)38:3/4<243::AID-DDR13>3.0.CO;2-# · DOI
  196. Rose, 2006, Precessation treatment with nicotine skin patch facilitates smoking cessation, Nicotine & Tobacco Research, 8, 89, 10.1080/14622200500431866 · DOI
  197. Rose, 2011, Nicotine preloading: The importance of a pre-cessation reduction in smoking behavior, Psychopharmacology, 217, 453, 10.1007/s00213-011-2350-0 · DOI
  198. Rose, 2009, Precessation treatment with nicotine patch significantly increases abstinence rates relative to conventional treatment, Nicotine & Tobacco Research, 11, 1067, 10.1093/ntr/ntp103 · DOI
  199. Rose, 2011, Nicotine preloading: The importance of a pre-cessation reduction in smoking behavior, Psychopharmacology, 217, 453, 10.1007/s00213-011-2350-0 · DOI
  200. Rose, 2010, Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score, Molecular Medicine, 16, 247, 10.2119/molmed.2009.00159 · DOI

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Metadata

Authors
Stead, L. F., Perera, R., Bullen, C., Mant, D., Hartmann-Boyce, J., Cahill, K., & Lancaster, T.
Venue
Cochrane Database of Systematic Reviews
Publisher
Wiley
Published
2012-11-14
Volume
11
Pages
CD000146-CD000146
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
DOI
10.1002/14651858.cd000146.pub4
OpenAlex
W1955803833
Cited by
2,464
References
32
FWCI
126.80
Type
journal article
Language
en
Update notices
new_version (2018-05-31)
Open access
bronze

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Stead, L. F., Perera, R., Bullen, C., Mant, D., Hartmann-Boyce, J., Cahill, K., & Lancaster, T. (2012). Nicotine replacement therapy for smoking cessation. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd000146.pub4

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