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Exercise for women receiving adjuvant therapy for breast cancer
Open accessAbstract
Main resultsFor this 2015 update we included a total of 32 studies with 2626 randomised women, 8 studies from the original search and 24 studies from the updated search.We found evidence that physical exercise during adjuvant treatment for breast cancer probably improves physical fitness (SMD 0.42, 95% confidence interval (CI) 0.25 to 0.59; 15 studies; 1310 women; moderate-quality evidence) and slightly reduces fatigue (SMD -0.28, 95% CI -0.41 to -0.16; 19 studies; 1698 women; moderate-quality evidence).Exercise may lead to little or no improvement in health-related quality of life (MD 1.10, 95% CI -5.28 to 7.48; 1 study; 68 women; low-quality evidence), a slight improvement in cancer site-specific quality of life (MD 4.24, 95% CI -1.81 to 10.29; 4 studies; 262 women; low-quality evidence), and an improvement in cognitive function (MD -11.55, 95% CI -22.06 to -1.05; 2 studies; 213 women; low-quality evidence).Exercise probably leads to little or no difference in cancer-specific quality of life (SMD 0.12, 95% CI 0.00 to 0.25; 12 studies; 1012 women; moderate-quality evidence) and little or no difference in depression (SMD -0.15, 95% CI -0.30 to 0.01; 5 studies; 674 women; moderate-quality evidence).Evidence for other outcomes ranged from low to moderate quality.Seven trials reported a very small number of adverse events.Importantly, physical exercise did not harm most women.Very few women experienced discomfort or pain in their arms or legs. What does this mean?Exercise for women receiving adjuvant therapy for breast cancer (Review)
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“We considered studies with between-group baseline differences that may affect the outcome, less than 75% adherence in the intervention group, and contamination in the control group (i.e., control group participants engaged in exercise), as high risk of ‘other sources of bias’ [29].”
From Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis (2019) · cites this paper as [29]
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Agier, S. (2019) · theses.fr (ABES) · doi:10.70675/3077b0ffz266fz4b6fz806fzc8189bd16910
Mallard, J. (2022) · theses.fr (ABES) · doi:10.70675/f8b2c96bzc4cdz4249z8e59z5f87c7ca2462
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Metadata
- Authors
- Furmaniak, A. C., Menig, M., & Markes, M. H.
- Affiliations
- University of Bonn (DE)
- Federal Office of Public Health (CH)
- Institute for Quality and Efficiency in Health Care (DE)
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- Wiley
- Published
- 2016-09-21
- Volume
- 2016
- Issue
- 9
- ISSN
- 1361-6137 (ISSN-L)
- 1465-1858
- OpenAlex
- W4319293029
- Cited by
- 276
- References
- 198
- Citations by year
- 2026: 11 · 2025: 14 · 2024: 39 · 2023: 30 · 2022: 48 · 2021: 31 · 2020: 36 · 2019: 33 · 2018: 17 · 2017: 16
- FWCI
- 2.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Funders
- National Breast Cancer Foundation
- National Health and Medical Research Council
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Keywords
- physical activity, breast cancer, adjuvant therapy, physical fitness, fatigue, health-related quality of life, cognitive function, depression, adverse events
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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