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Alcoholics Anonymous and other 12-step programmes for alcohol dependence

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Ferri, Marica, Amato, Laura, Davoli, Marina·2006·Cochrane Database of Systematic Reviews

Abstract

BACKGROUND: Alcoholics Anonymous (AA) is an international organization of recovering alcoholics that offers emotional support through self-help groups and a model of abstinence for people recovering from alcohol dependence, using a 12-step approach. Although it is the most common, AA is not the only 12-step intervention available there are other 12-step approaches (labelled Twelve Step Facilitation (TSF)). OBJECTIVES: To assess the effectiveness of AA or TSF programmes compared to other psychosocial interventions in reducing alcohol intake, achieving abstinence, maintaining abstinence, improving the quality of life of affected people and their families, and reducing alcohol associated accidents and health problems. SEARCH STRATEGY: We searched the Specialized Register of Trials of the Cochrane Group on Drugs and Alcohol, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE from 1966, EMBASE from 1980, CINAHL from 1982, PsychINFO from 1967. Searches were updated in February 2005. We also inspected lists of references for relevant studies. SELECTION CRITERIA: Studies involving adults (<18) of both genders with alcohol dependence attending on a voluntary or coerced basis AA or TSF programmes comparing no treatment, other psychological interventions, 12-step variants. DATA COLLECTION AND ANALYSIS: One reviewer (MF) assessed studies for inclusion and extracted data using a pre-defined data extraction form. Studies were evaluated for methodological quality and discussed by all reviewers. MAIN RESULTS: Eight trials involving 3417 people were included. AA may help patients to accept treatment and keep patients in treatment more than alternative treatments, though the evidence for this is from one small study that combined AA with other interventions and should not be regarded as conclusive. Other studies reported similar retention rates regardless of treatment group. Three studies compared AA combined with other interventions against other treatments and found few differences in the amount of drinks and percentage of drinking days. Severity of addiction and drinking consequence did not seem to be differentially influenced by TSF versus comparison treatment interventions, and no conclusive differences in treatment drop out rates were reported. Included studies did not allow a conclusive assessment of the effect of TSF in promoting complete abstinence. AUTHORS' CONCLUSIONS: No experimental studies unequivocally demonstrated the effectiveness of AA or TSF approaches for reducing alcohol dependence or problems. One large study focused on the prognostic factors associated with interventions that were assumed to be successful rather than on the effectiveness of interventions themselves, so more efficacy studies are needed.

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  • The protective function of 12-Step attendance has been well documented.

    “The protective function of 12-Step attendance has been well documented”

    From Development and initial evaluation of the Brief Addiction Monitor (BAM) (2013) · cites this paper as Ferri, Amato, & Davoli, 2006

    The authors’ conclusions (Background; page unavailable) state that no experimental studies unequivocally demonstrated the effectiveness of AA or other 12-step approaches in reducing alcohol problems. The Discussion adds that evidence for an abstinence benefit was inconclusive. This contradicts the claim that a protective function of attendance was well documented; it does not establish that attendance is ineffective. (LLM, conf=0.89)

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Research works printed but not linked: 60

  1. Brown TG, Seraganian P, Tremblay J, Annis H. Matching substance abuse aftercare treatments to client characteristics. Addictive Behaviors 2002;27:585‐604. [DOI] [PubMed] [Google Scholar]
  2. Brown TG, Seraganian P, Tremblay J, Annis H. Process and outcome changes with relapse prevention versus 12‐Step aftercare programs for substance abusers. Addiction 2002;97:677‐89. [DOI] [PubMed] [Google Scholar]
  3. Cloud RN, Ziegler CH, Blondell RD. What is Alcoholics Anonymous affiliation?. Substance Use & Misuse 2004;39(7):1117‐36. [DOI] [PubMed] [Google Scholar]
  4. Davis WT, Campbell L, Tax J, Lieber CS. A trial of "standard" outpatient alcoholism treatment vs. a minimal treatment control. Journal of Substance Abuse Treatment 2002;23(1):9‐19. [DOI] [PubMed] [Google Scholar]
  5. Kahler CW, Read JP, Ramsey SE, Stuart GL, McCrady BS, Brown RA. Motivational enhancement for 12‐step involvement among patients undergoing alcohol detoxification. Journal of Consulting and Clinical Psychology 2004;72(4):736‐41. [DOI] [PubMed] [Google Scholar]
  6. Cutler RB, Fishbain DA. Are alcoholism treatments effective? The Project MATCH data. Are alcoholism treatments effective? The Project MATCH data. BMC Public Health 2005; Vol. 5, issue 1:75. [DOI] [PMC free article] [PubMed]
  7. Project MATCH Research Group. Matching alcoholism treatments to client heterogeneity: treatment main effects and matching effects on drinking during treatment. Journal of Studies on Alcohol 1998;59:631‐9. [DOI] [PubMed] [Google Scholar]
  8. Project MATCH research group. Matching alcoholism treatments to client heterogeneity: Project MATCH three‐year drinking outcomes. Alcoholism: Clinical & Experimental Research 1998;22:1300‐11. [DOI] [PubMed] [Google Scholar]
  9. McCrady BS, Epstein EE, Hirsch LS. Issues in the implementation of a randomised clinical trial that includes Alcoholics Anonymous: studying AA‐related behavior during treatment. Journal of Studies on Alcohol 1996;57(6):604‐12. [DOI] [PubMed] [Google Scholar]
  10. McCrady BS, Epstein EE, Kahler CW. Alcoholics anonymous and relapse prevention as maintenance strategies after conjoint behavioral alcohol treatment for men: 18‐month outcomes. Journal of Consulting and Clinical Psychology 2004;72(5):870‐8. [DOI] [PubMed] [Google Scholar]
  11. Walsh DC, Hingson RW, Merrigan DM, Levenson SM, Cupples LA, Heeren T, et al. A randomised trial of treatment options for alcohol‐abusing workers. The New England Journal of Medicine 1991;325(11):775‐82. [DOI] [PubMed] [Google Scholar]
  12. Zemore SE, Kaskutas LA. Helping, spirituality and alcoholics anonymous in recovery. Journal of Studies on Alcohol 2004;65(3):383‐91. [DOI] [PubMed] [Google Scholar]
  13. Zemore SE, Kaskutas LA, Ammon LN. In 12‐step groups, helping helps the helper. Addiction 2004;99(8):1015‐23. [DOI] [PubMed] [Google Scholar]
  14. Bond J, Kaskutas LA, Weisner C. The persistent influence of social networks and alcoholics anonymous on abstinence. J Stud Alcohol 2003;64(4):579‐88. [DOI] [PubMed] [Google Scholar]
  15. Bradley KA, Kivlahan DR, Zhou XH, et al. Using alcohol screening results and treatment history to assess the severity of at‐risk drinking in Veterans Affairs primary care patients. Alcohol Clin Exp Res 2004;28(3):448‐55. [DOI] [PubMed] [Google Scholar]
  16. Campos EA. [Representations of alcoholism in a former alcoholics' association: Alcoholics Anonymous]. Cad Saude Publica 2004;20(5):1379‐87. [DOI] [PubMed] [Google Scholar]
  17. Gossop M, Harris J, Best D, et al. Is attendance at Alcoholics Anonymous meetings after inpatient treatment related to improved outcomes? A 6‐month follow‐up study. Alcohol Alcohol 2003;38(5):421‐6. [DOI] [PubMed] [Google Scholar]
  18. Graham, K, Annis, H. M, Brett, P. J, Venesoen. P. A controlled field trial of group versus individual cognitive‐behavioural training for relapse prevention.. Addiction 1996 Aug;91(8):1127‐39. [DOI] [PubMed] [Google Scholar]
  19. Humphreys K, Wing S, McCarty D, et al. Self‐help organizations for alcohol and drug problems: toward evidence‐based practice and policy. J Subst Abuse Treat 2004;26(3):151‐8; discussion 159‐65. [DOI] [PubMed] [Google Scholar]
  20. Karno MP, Longabaugh R. Patient depressive symptoms and therapist focus on emotional material: a new look at Project MATCH. J Stud Alcohol 2003;64(5):607‐15. [DOI] [PubMed] [Google Scholar]
  21. Keso, L, Salaspuro. M. Inpatient treatment of employed alcoholics: a randomised clinical trial on Hazelden‐type and traditional treatment.. Alcohol Clin Exp Res 1990 Aug;14(4):584‐9. [DOI] [PubMed] [Google Scholar]
  22. Lloyd G. One hundred alcoholic doctors: a 21‐year follow‐up. Alcohol Alcohol 2002;37(4):370‐4. [DOI] [PubMed] [Google Scholar]
  23. Longabaugh, R, Wirtz, P. W, Zweben, A, Stout. R. L. Network support for drinking, Alcoholics Anonymous and long‐term matching effects.. Addiction 1998 Sep;93(9):1313‐33. [DOI] [PubMed] [Google Scholar]
  24. Masudomi I, Isse K, Uchiyama M, Watanabe H. Self‐help groups reduce mortality risk: a 5‐year follow‐up study of alcoholics in the Tokyo metropolitan area. Psychiatry Clin Neurosci 2004;58(5):551‐7. [DOI] [PubMed] [Google Scholar]
  25. McKellar J, Stewart E, Humphreys K. Alcoholics anonymous involvement and positive alcohol‐related outcomes: cause, consequence, or just a correlate? A prospective 2‐year study of 2,319 alcohol‐dependent men. J Consult Clin Psychol 2003;71(2):302‐8. [DOI] [PubMed] [Google Scholar]
  26. McLatchie, BH, Lomp. K. G. An experimental investigation of the influence of aftercare on alcoholic relapse.. Br J Addict 1988 Sep;83(9):1045‐54. [DOI] [PubMed] [Google Scholar]
  27. Moos RH, Moos BS. The interplay between help‐seeking and alcohol‐related outcomes: divergent processes for professional treatment and self‐help groups. Drug Alcohol Depend 2004;75(2):155‐64. [DOI] [PubMed] [Google Scholar]
  28. Morgan MY, Landron F, Lehert P. Improvement in quality of life after treatment for alcohol dependence with acamprosate and psychosocial support. Alcohol Clin Exp Res 2004;28(1):64‐77. [DOI] [PubMed] [Google Scholar]
  29. Ouimette PC, Finney JW, Moos RH. Twelve‐step and cognitive‐‐behavioral treatment for substance abuse: a comparison of treatment effectiveness. J Consult Clin Psychol 1997 Apr;65(2):230‐40. [DOI] [PubMed] [Google Scholar]
  30. Staines G, Magura S, Rosenblum A, et al. Predictors of drinking outcomes among alcoholics. Am J Drug Alcohol Abuse 2003;29(1):203‐18. [DOI] [PubMed] [Google Scholar]
  31. Thomassen L. AA utilization after introduction in outpatient treatment. Subst Use Misuse 2002;37(2):239‐53. [DOI] [PubMed] [Google Scholar]
  32. Timko C, Moos RH, Finney JW, Connell EG. Gender differences in help‐utilization and the 8‐year course of alcohol abuse. Addiction 2002;97(7):877‐89. [DOI] [PubMed] [Google Scholar]
  33. Timko C, Sempel JM. Intensity of acute services, self‐help attendance and one‐year outcomes among dual diagnosis patients. J Stud Alcohol 2004;65(2):274‐82. [DOI] [PubMed] [Google Scholar]
  34. Tucker JA, Vuchinich RE, Rippens PD. A factor analytic study of influences on patterns of help‐seeking among treated and untreated alcohol dependent persons. J Subst Abuse Treat 2004;26(3):237‐42. [DOI] [PubMed] [Google Scholar]
  35. Verinis, J. S. and Taylor, J. Increasing alcoholic patients' aftercare attendance.. Int J Addict 1994 Sep;29(11):1487‐94. [DOI] [PubMed] [Google Scholar]
  36. Amato L, Davoli M, Ali R, Auriacombe M, Faggiano F, Farrell M, et al. Drugs and Alcohol Group. About the Cochrane Collaboration (Collaborative Review Groups (CRGs)). The Cochrane Library 2005, issue 3.
  37. Cutler RB, Fishbain DA. Are alcoholism treatments effective? The Project MATCH data.. BMC Public Health 2005; Vol. 5, issue 1:75. [DOI] [PMC free article] [PubMed]
  38. American psychiatric association. Diagnostic and Statistical Manual of Mental Disorders DSM‐IV‐TM. Washington DC: American psychiatric association, 1994. [Google Scholar]
  39. Emrick CD. Alcoholics Anonymous: membership characteristics and effectiveness as treatment. Recent Developments in Alcoholism 1989;7:37‐53. [DOI] [PubMed] [Google Scholar]
  40. Ferri M, Davoli M, Perucci C. Heroin maintenance treatment for chronic heroin‐dependent individuals: A Cochrane systematic review of effectiveness. Journal of Substance Abuse Treatment 2006;30:63‐72. [DOI] [PubMed] [Google Scholar]
  41. Gitlow S. Substance use disorders. Practical Guides in Psychiatry. Philadelphia: Lippincott Williams & Wilkins, 2001. [Google Scholar]
  42. Greenhalgh Trisha. How to read a paper. London: BMJ book, 1997. [Google Scholar]
  43. Hales RE, Yudofsky SC, Talbott JA. The American Psychiatric Press Textbook of Psychiatry. Thirth. Washington DC: American Psychiatric Press, 1999. [Google Scholar]
  44. Heath AC, Bucholz KK, Madden PA, Dinwiddie SH, Slutske WS, Berut LJ, et al. Genetic and Environmental contributions to alcohol dependence risk in a national twin sample: Consistency of findings in women and men. Psychology and Medicine 1997;27(6):1381‐96. [DOI] [PubMed] [Google Scholar]
  45. Alejandro Jadad. Randomised Controlled Trials. Vol. 2, London: BMJ books, 1998. [Google Scholar]
  46. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, et al. Lifetime and 12‐month prevalence of DSM‐III‐R psychiatric disorders in the United States. Archive of General Psychiatry 1994;51:8‐19. [DOI] [PubMed] [Google Scholar]
  47. Kownacki, RJ, Shadish WR. Does Alcoholics Anonymous work? The results from a meta‐analysis of controlled experiments. Substance Use & Misuse 1999;34(13):1897‐916. [DOI] [PubMed] [Google Scholar]
  48. Marlatt GA, Gordon JR. Relapse Prevention: maintenance strategies in the treatment of cocaine of addictive behaviours. New York: Guilford, 1995. [Google Scholar]
  49. Project MATCH Research Group. Project MATCH secondary a priori hypotheses. Addiction 1997;92:1671‐98. [PubMed] [Google Scholar]
  50. Project MATCH research group. Matching Alcoholism Treatments to Client Heterogeneity: Project MATCH posttreatment drinking outcomes. Journal of Studies on Alcohol 1997;58:7‐29. [PubMed] [Google Scholar]
  51. Project MATCH research group. Matching alcoholism treatments to client heterogeneity: Project MATCH three‐year drinking outcomes. Alcoholism: Clinical & Experimental Research 1998;22:1300‐11. [DOI] [PubMed] [Google Scholar]
  52. McLellan AT, Luborsky L, Woody GE, O'Brien CP. An improved diagnostic evaluation instrument for substance abuse patients: the Addiction Severity Index. Journal of Nervous and Mental Diseases 1980;168(1):26‐33. [DOI] [PubMed] [Google Scholar]
  53. Moyer A, Finney JW, Elworth JT, Kraemer HC. Can methodological features account for patient‐treatment matching findings in the alcohol field?. Journal of Studies on Alcohol 2001;62(1):62‐73. [DOI] [PubMed] [Google Scholar]
  54. NIAA. Why Do Some People Dr i n k Too Mu c h ? The Role of Genetic and Psychosocial Influences. Alcohol Research & Health 2000;24(1):17‐26. [PMC free article] [PubMed] [Google Scholar]
  55. National Institute of Alcohol Abuse and Alcoholism. Helping people with alcohol problems. A Health practitioner's guide (www.niaa.nih.gov). NIH Publication January 2003;03:3769. [Google Scholar]
  56. Parks GA, Anderson BK, Marlatt AG. Relapse prevention therapy. In: Heather N, Peters TJ, Stockwell T editor(s). International handbook of alcohol dependence and problems. Chichester: John Wiley and Sons, 2001. [Google Scholar]
  57. Regier DA, Narrow WE, Rae DS, Manderscheid RW, Locke BZ, Goodwin FK. The de facto US mental and addictive disorders service system: epidemiologic catchment area prospective 1‐year prevalence rates of disorders and services. Archive General Psychaitry 1993;50:85‐94. [DOI] [PubMed] [Google Scholar]
  58. The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 4.2 for Windows. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2003.
  59. Rehn N, Room R, Edwards G. Alcohol in the European Region – consumption, harm and policies. World Health Organization, June 2001. [Google Scholar]
  60. EURO/WHO. Alcohol policy in the WHO European Region: current status and the way forward. Fact sheet EURO/10/05. Copenhagen, Bucharest: World Health Organization, 12 September 2005. [Google Scholar]

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Authors
Ferri, M., Amato, L., & Davoli, M.
Affiliations
  • Agency of Public Health; Project Unit: EBM and Models of Health Assistance; Via di Santa Costanza 53 Rome Italy 00198
  • Azienda Sanitaria Locale Roma 3 (IT)
Venue
Cochrane Database of Systematic Reviews
Publisher
Wiley
Published
2006-07-19
Volume
2010
Issue
1
Pages
CD005032-CD005032
ISSN
  • 1361-6137 (ISSN-L)
  • 1465-1858
OpenAlex
W1541598409
Cited by
347
References
0
Citations by year
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FWCI
1.28
Type
journal article
Language
en
Open access
Locations
  • Cochrane Database of Systematic Reviews (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
  • Health Sciences › Health Professions › General Health Professions › Homelessness and Social Issues
Keywords
Alcoholics Anonymous, twelve-step facilitation, 12-step programs, alcoholism, self-help groups, abstinence, treatment retention, treatment discontinuation, alcohol consumption, psychosocial interventions, family quality of life, alcohol-related accidents
MeSH terms
Adult, Alcoholics Anonymous, Alcoholism, Humans, Self-Help Groups, Program Evaluation, Randomized Controlled Trials as Topic

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