The DOI matches its Crossref record; 238 of the 240 references it cites were found in a registry or an index.
Antioxidants for male subfertility
Open accessAbstract
versus placebo or no treatment, Outcome 2 Live birth; placebo or no treatment........ Analysis 1.3.Comparison 1 Antioxidant(s) versus placebo or no treatment, Outcome 3 Live birth; IVF/ICSI.................................. Analysis 1.4.Comparison 1 Antioxidant(s) versus placebo or no treatment, Outcome 4 Live birth; as-treated analysis................ Analysis 1.5.Comparison 1 Antioxidant(s) versus placebo or no treatment, Outcome 5 Clinical pregnancy; type of antioxidant.... Analysis 1.6.Comparison 1 Antioxidant(s) versus placebo or no treatment, Outcome 6 Clinical pregnancy; placebo or no treatment.....................................
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In the citing paper
“Taken together with previous findings, our results indicate that while antioxidants may reduce ROS, this does not appear to translate into reduced sperm DNA fragmentation.”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
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In the citing paper
“The recent Cochrane meta-analysis, which included 5 trials with a variety of antioxidants with a total of 254 subjects, found that men treated with antioxidants had on average 5% lower DNA fragmentation, but the confidence interval was broad and crossed 0. (7)”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The recent Cochrane Review found that antioxidant use increased the odds of pregnancy by 2.97 fold and the odd of live birth by 1.8 fold. (7)”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
The cited source says what the claim attributes to it.
In the citing paper
“The recent Cochrane Review found that antioxidant use increased the odds of pregnancy by 2.97 fold and the odd of live birth by 1.8 fold. (7)”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
The cited source says what the claim attributes to it.
In the citing paper
“However, the Cochrane meta-analysis did find a 12% absolute increase in motility in men treated with combination antioxidants for 3 months compared to controls. (7)”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
The cited source says what the claim attributes to it.
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“A recent meta-analysis concluded that antioxidant supplementation taken by subfertile males may increase the chance of live birth; however, large randomized, well-designed, placebo-controlled trials were needed. (7)”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
The cited source says what the claim attributes to it.
In the citing paper
“Our negative findings contradict the overall conclusions from the Cochrane Review and meta-analysis.”
From The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial (2020) · cites this paper as [7]
In the citing paper
“Low-quality evidence suggests that antioxidant supplementation for men with infertility may improve live birth rates (Smits 2019).”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Smits 2019
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Citations
Cites
2 retracted
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Flagged first, then by citations
2 of the 240 references couldn’t be matched to a known paper.
Research works printed but not linked: 25
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Agarwal, A. K., Baskaran, S., Parekh, N. V., Cho, C., Henkel, R., Vij, S. C., Arafa, M. M., Selvam, M. K. P., & Shah, R. S. (2020) · The Lancet · doi:10.1016/s0140-6736(20)32667-2 · Cited by 1,497
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Sperm DNA Fragmentation: A New Guideline for Clinicians
Agarwal, A. K., Majzoub, A. A., Baskaran, S., Selvam, M. K. P., Cho, C., Henkel, R., Finelli, R., Leisegang, K., Sengupta, P., Zenoaga-Barbăroşie, C., et al. (2020) · The World Journal of Men s Health · doi:10.5534/wjmh.200128 · Cited by 341
Male infertility due to testicular disorders
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Oxidative stress and male infertility
Takeshima, T., Usui, K., Mori, K., Asai, T., Yasuda, K., Kuroda, S., & Yumura, Y. (2020) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12353 · Cited by 234
Metadata
- Authors
- Smits, R. M., Mackenzie-Proctor, R., Yazdani, A., Stankiewicz, M. T., Jordan, V., & Showell, M. G.
- Affiliations
- Radboud University Medical Center (NL)
- Auckland City Hospital (NZ)
- Queensland Fertility Group Research Foundation; 55 Little Edward St, Level 2 Boundary Court Spring Hill Brisbane Queensland Australia 4000
- Ashford Specialist Centre Suite 22; 57-59 Anzac Highway Ashford Adelaide SA Australia
- University of Auckland (NZ)
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- Wiley
- Published
- 2019-03-14
- Volume
- 2019
- Issue
- 3
- ISSN
- 1361-6137 (ISSN-L)
- 1465-1858
- OpenAlex
- W3049686564
- Cited by
- 277
- References
- 240
- Citations by year
- 2026: 8 · 2025: 21 · 2024: 28 · 2023: 47 · 2022: 52 · 2021: 52 · 2020: 52 · 2019: 15
- FWCI
- 6.05
- Type
- journal article
- Language
- en
- Update notices
- new_version (2022-05-04)
- Open access
- bronze
- doi.org
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- ResearchSpace (University of Auckland) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- antioxidants, male subfertility, male infertility, live birth, clinical pregnancy, in vitro fertilization, intracytoplasmic sperm injection, antioxidant supplementation
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