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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

A Graphene Nanoprobe for Rapid, Sensitive, and Multicolor Fluorescent DNA Analysis

He, Shijiang, Song, Bo, Li, Di, Zhu, Changfeng, Qi, Wenpeng, Wen, Yanqin, Wang, Lihua, Song, Shiping, Fang, Haiping, Fan, Chunhai·2010·Advanced Functional Materials

Abstract

Coupling nanomaterials with biomolecular recognition events represents a new direction in nanotechnology toward the development of novel molecular diagnostic tools. Here a graphene oxide (GO)‐based multicolor fluorescent DNA nanoprobe that allows rapid, sensitive, and selective detection of DNA targets in homogeneous solution by exploiting interactions between GO and DNA molecules is reported. Because of the extraordinarily high quenching efficiency of GO, the fluorescent ssDNA probe exhibits minimal background fluorescence, while strong emission is observed when it forms a double helix with the specific targets, leading to a high signal‐to‐background ratio. Importantly, the large planar surface of GO allows simultaneous quenching of multiple DNA probes labeled with different dyes, leading to a multicolor sensor for the detection of multiple DNA targets in the same solution. It is also demonstrated that this GO‐based sensing platform is suitable for the detection of a range of analytes when complemented with the use of functional DNA structures.

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Metadata

Authors
He, S., Song, B., Li, D., Zhu, C., Qi, W., Wen, Y., Wang, L., Song, S., Fang, H., & Fan, C.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2010-01-27
Volume
20
Issue
3
Pages
453-459
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W1982636587
Cited by
1,376
References
3
FWCI
48.44
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Graphene Nanoprobe for Rapid, Sensitive, and Multicolor Fluorescent DNA Analysis. https://app.cochat.ai/papers/10.1002/adfm.200901639
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He, S., Song, B., Li, D., Zhu, C., Qi, W., Wen, Y., Wang, L., Song, S., Fang, H., & Fan, C. (2010). A Graphene Nanoprobe for Rapid, Sensitive, and Multicolor Fluorescent DNA Analysis. Advanced Functional Materials. https://doi.org/10.1002/adfm.200901639

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