The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A Graphene Nanoprobe for Rapid, Sensitive, and Multicolor Fluorescent DNA Analysis
Abstract
Coupling nanomaterials with biomolecular recognition events represents a new direction in nanotechnology toward the development of novel molecular diagnostic tools. Here a graphene oxide (GO)‐based multicolor fluorescent DNA nanoprobe that allows rapid, sensitive, and selective detection of DNA targets in homogeneous solution by exploiting interactions between GO and DNA molecules is reported. Because of the extraordinarily high quenching efficiency of GO, the fluorescent ssDNA probe exhibits minimal background fluorescence, while strong emission is observed when it forms a double helix with the specific targets, leading to a high signal‐to‐background ratio. Importantly, the large planar surface of GO allows simultaneous quenching of multiple DNA probes labeled with different dyes, leading to a multicolor sensor for the detection of multiple DNA targets in the same solution. It is also demonstrated that this GO‐based sensing platform is suitable for the detection of a range of analytes when complemented with the use of functional DNA structures.
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Cites
Electric Field Effect in Atomically Thin Carbon Films
Novoselov, K. S., Geim, A. K., Morozov, S. V., Jiang, D., Zhang, Y., Dubonos, S. V., Grigorieva, I. V., & Firsov, A. A. (2004) · Science · doi:10.1126/science.1102896 · Cited by 66,834
Graphene-based composite materials
Stankovich, S., Dikin, D. A., Dommett, G. H. B., Kohlhaas, K. M., Zimney, E. J., Stach, E. A., Piner, R. D., Nguyen, S. T., & Ruoff, R. S. (2006) · Nature · doi:10.1038/nature04969 · Cited by 12,922
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Cited by
New Horizons for Diagnostics and Therapeutic Applications of Graphene and Graphene Oxide
Feng, L., Wu, L., & Qu, X. (2013) · Advanced Materials · doi:10.1002/adma.201203229 · Cited by 632
Liu, M., Zeng, G., Wang, K., Wan, Q., Tao, L., Zhang, X., & Wei, Y. (2016) · Nanoscale · doi:10.1039/c5nr09078d · Cited by 561
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Graphene Oxide as an Optical Biosensing Platform
Morales‐Narváez, E., & Merkoçi, A. (2012) · Advanced Materials · doi:10.1002/adma.201200373 · Cited by 508
Yola, M. L., Gupta, V. K., Eren, T., Şen, A. E., & Atar, N. (2014) · Electrochimica Acta · doi:10.1016/j.electacta.2013.12.086 · Cited by 417
Metadata
- Authors
- He, S., Song, B., Li, D., Zhu, C., Qi, W., Wen, Y., Wang, L., Song, S., Fang, H., & Fan, C.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2010-01-27
- Volume
- 20
- Issue
- 3
- Pages
- 453-459
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W1982636587
- Cited by
- 1,376
- References
- 3
- FWCI
- 48.44
- Type
- journal article
- Language
- en
- Open access
- closed
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