The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Porphyrinic Metal–Organic Frameworks Coated Gold Nanorods as a Versatile Nanoplatform for Combined Photodynamic/Photothermal/Chemotherapy of Tumor
Abstract
In this paper, a simple, but effective method is reported to construct the core−shell gold nanorod@metal–organic frameworks (AuNR@MOFs) as a multifunctional theranostic platform by using functionalized AuNRs as seed crystal for the growth of porphyrinic MOFs on the surface of AuNR. Such a delicate tunable core−shell composite not only possesses the improved drug loading efficiency, near‐infrared light‐trigger drug release, and fluorescence imaging, but also can produce reactive oxygen species as well as photothermal activity to achieve combined cancer therapy. It is further demonstrated that the camptothecin loaded AuNR@MOFs show distinctively synergistic efficiency for damaging the cancer cell in vitro and inhibiting the tumor growth and metastasis in vivo. The development of this high‐performance incorporated nanostructure will provide more perspectives in the design of versatile nanomaterials for biomedical applications.
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Cites
Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Cited by
Phototherapy in cancer treatment: strategies and challenges
Cai, Y., Chai, T., Nguyen, W., Liu, J., Xiao, E., Ran, X., Ran, Y., Du, D., Chen, W., & Chen, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02140-y · Cited by 453
Recent advances in nanomaterials for enhanced photothermal therapy of tumors
Hu, J.-J., Cheng, Y.-J., & Zhang, X.-Z. (2018) · Nanoscale · doi:10.1039/c8nr07627h · Cited by 409
Self-citationConferring Ti‐Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy
Liang, S., Xiao, X., Bai, L., Liu, B., Yuan, M., Ma, P., Pang, M., Cheng, Z., & Lin, J. (2021) · Advanced Materials · doi:10.1002/adma.202100333 · Cited by 359
A Mn(III)-Sealed Metal–Organic Framework Nanosystem for Redox-Unlocked Tumor Theranostics
Wan, S.-S., Cheng, Q., Zeng, X., & Zhang, X.-Z. (2019) · ACS Nano · doi:10.1021/acsnano.9b00300 · Cited by 322
Self-citationZhou, Z., Vázquez-González, M., & Willner, I. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01030h · Cited by 308
Metadata
- Authors
- Zeng, J., Zhang, M., Peng, M., Gong, D., & Zhang, X.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2017-12-19
- Volume
- 28
- Issue
- 8
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2776575854
- Cited by
- 287
- References
- 1
- FWCI
- 13.97
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zeng, J., Zhang, M., Peng, M., Gong, D., & Zhang, X. (2018). Porphyrinic Metal–Organic Frameworks Coated Gold Nanorods as a Versatile Nanoplatform for Combined Photodynamic/Photothermal/Chemotherapy of Tumor. Advanced Functional Materials. https://doi.org/10.1002/adfm.201705451
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