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Visible‐ and Near‐Infrared Light‐Driven Molecular Photoswitches for Biological Applications
Abstract
Molecular photoswitches can undergo isomerization under light exposure, making them uniquely attractive for high spatiotemporal resolution remote control of biological functions. Visible and near‐infrared (NIR) light, with their low energy consumption, high safety, and strong tissue penetration, are particularly suitable for biological applications. Therefore, developing visible‐ and NIR light‐driven molecular photoswitches for biological use is of great significance. This review introduces the most common visible‐ and NIR light‐driven molecular photoswitches and presents the state‐of‐art of their applications in bioimaging, biosensing, drug delivery, photocontrolled cancer phototherapy, and photopharmacology. The opportunities and challenges of the photoswitches for their future development in biological applications are outlined.
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- Baumgartner B., 2024, ChemRxiv, 1
- Baumgartner B., 2023, ChemRxiv, 1
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Second Near‐Infrared Window Fluorescence Materials for In Vivo Dynamic Multiplexed Imaging
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Self-citationOrganic small-molecule NIR-II fluorophores for tumor phototheranostics
Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22
Self-citation
Metadata
- Authors
- Xu, Y., Tang, Y., & Li, Q.
- Affiliations
- Southeast University (CN)
- Kent State University (US)
- Corresponding author
- Tang, Yuqi
- Li, Quan
- ORCID
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2024-12-19
- Volume
- 35
- Issue
- 22
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W4405616913
- Cited by
- 49
- References
- 340
- Citations by year
- 2026: 28 · 2025: 21
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Functional Materials (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Photochromic and Fluorescence Chemistry
- Physical Sciences › Chemistry › Organic Chemistry › Supramolecular Chemistry and Complexes
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer composites and self-healing
- Keywords
- photoswitches, visible light, near-infrared light, photoisomerization, bioimaging, biosensing, drug delivery, phototherapy, photopharmacology
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