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Cited by 351

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Current Progress in Reactive Oxygen Species (ROS)‐Responsive Materials for Biomedical Applications

Open access
Lee, Sue Hyun, Gupta, Mukesh K., Bang, Jae Beum, Bae, Hojae, Sung, Hak‐Joon·2013·Advanced Healthcare Materials

Abstract

Recently, significant progress has been made in developing “stimuli‐sensitive” biomaterials as a new therapeutic approach to interact with dynamic physiological conditions. Reactive oxygen species (ROS) production has been implicated in important pathophysiological events, such as atherosclerosis, aging, and cancer. ROS are often overproduced locally in diseased cells and tissues, and they individually and synchronously contribute to many of the abnormalities associated with local pathogenesis. Therefore, the advantages of developing ROS‐responsive materials extend beyond site‐specific targeting of therapeutic delivery, and potentially include navigating, sensing, and repairing the cellular damages via programmed changes in material properties. Here we review the mechanism and development of biomaterials with ROS‐induced solubility switch or degradation, as well as their performance and potential for future biomedical applications.

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Crossref · 10.1002/adhm.201200423

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Metadata

Authors
Lee, S. H., Gupta, M. K., Bang, J. B., Bae, H., & Sung, H.
Venue
Advanced Healthcare Materials
Publisher
Wiley
Published
2013-01-25
Volume
2
Issue
6
Pages
908-915
ISSN
  • 2192-2640 (ISSN-L)
  • 2192-2659
OpenAlex
W2147503434
Cited by
351
References
6
FWCI
8.16
Type
journal article
Language
en
Open access
green

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.