Cited by 218Antimicrobial agents and applicationsBacterial biofilms and quorum sensingNitric Oxide and Endothelin Effects

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Nitric Oxide–Releasing Macromolecular Scaffolds for Antibacterial Applications

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Yang, Lei, Feura, Evan S., Ahonen, Mona Jasmine R., Schoenfisch, Mark H.·2018·Advanced Healthcare Materials

DOI 10.1002/adhm.201800155PMC PMC6159924

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Abstract

Exogenous nitric oxide (NO) represents an attractive antibacterial agent because of its ability to both disperse and directly kill bacterial biofilms while avoiding resistance. Due to the challenges associated with administering gaseous NO, NO‐releasing macromolecular scaffolds are developed to facilitate NO delivery. This progress report describes the rational design and application of NO‐releasing macromolecular scaffolds as antibacterial therapeutics. Special consideration is given to the role of the physicochemical properties of the NO storage vehicles on antibacterial or anti‐biofilm activity.

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1 retracted

Conjugating S-Nitrosothiols with Glutathiose Stabilized Silver Sulfide Quantum Dots for Controlled Nitric Oxide Release and Near-Infrared Fluorescence Imaging
Tan, L., Wan, A., & Li, H. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am4034153 · Cited by 66
Retracted
The biofilm matrix
Flemming, H.-C., & Wingender, J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2415 · Cited by 10,137
The bactericidal effect of silver nanoparticles
Morones‐Ramírez, J. R., Elechiguerra, J. L., Camacho, A., Holt, K. B., Kouri, J. B., Tapia-Ramı́rez, J., & Yacamán, M. J. (2005) · Nanotechnology · doi:10.1088/0957-4484/16/10/059 · Cited by 6,690
Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism
Sirelkhatim, A. H., Mahmud, S., Seeni, A., Kaus, N. H. M., Ann, L. C., Bakhori, S. K. M., Hasan, H. B., & Mohamad, D. (2015) · Nano-Micro Letters · doi:10.1007/s40820-015-0040-x · Cited by 4,792
Nitric oxide synthases: regulation and function
Forstermann, U., & Sessa, W. C. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr304 · Cited by 4,409
Size-controlled silver nanoparticles synthesized over the range 5–100 nm using the same protocol and their antibacterial efficacy
Agnihotri, S., Mukherji, S., & Mukherji, S. (2013) · RSC Advances · doi:10.1039/c3ra44507k · Cited by 1,887
Structures of Gram-Negative Cell Walls and Their Derived Membrane Vesicles
Beveridge, T. J. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.16.4725-4733.1999 · Cited by 1,533
Nitric oxide donors: chemical activities and biological applications
Wang, P. G., Xian, M., Tang, X., Wu, X., Wen, Z., Cai, T., & Janczuk, A. J. (2002) · Chemical Reviews · doi:10.1021/cr000040l · Cited by 1,337
DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its Progenitors
Wink, D. A., Kasprzak, K. S., Maragos, C. M., Elespuru, R. K., Misra, M., Dunams, T. M., Cebula, T. A., Koch, W. H., Andrews, A. W., Allen, J. S., et al. (1991) · Science · doi:10.1126/science.1948068 · Cited by 1,243
The global threat of antimicrobial resistance: science for intervention.
Roca, I., Akova, M., Baquero, F., Carlet, J., Cavaleri, M., Coenen, S., Cohen, J., Findlay, D., Gyssens, I., Heure, O. E., et al. (2015) · New Microbes and New Infections · doi:10.1016/j.nmni.2015.02.007 · Cited by 1,106

Show all 160 references

Research works printed but not linked: 3

Marcato P. D., 2013, Curr. Nanosci., 9, 1
10.1021/ja3022736 · DOI
Nurhasni H., 2015, Int. J. Nanomed., 10, 3065

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Tailoring nitric oxide release with additive manufacturing to create antimicrobial surfaces
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Authors: Yang, L., Feura, E. S., Ahonen, M. J. R., & Schoenfisch, M. H.
Affiliations: University of North Carolina at Chapel Hill (US)
Corresponding author: Schoenfisch, Mark H.
ORCID: Yang, Lei
Schoenfisch, Mark H.
Venue: Advanced Healthcare Materials
Publisher: Wiley
Published: 2018-05-14
Volume: 7
Issue: 13
Pages: e1800155-e1800155
ISSN: 2192-2640 (ISSN-L)
2192-2659
DOI: 10.1002/adhm.201800155
PMC: PMC6159924
OpenAlex: W2803124751
Cited by: 218
References: 160
Citations by year: 2026: 18 · 2025: 38 · 2024: 38 · 2023: 29 · 2022: 30 · 2021: 31 · 2020: 19 · 2019: 12 · 2018: 2
FWCI: 1.09
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Advanced Healthcare Materials (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (AI112029, DE025207)
Topics: Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Keywords: nitric oxide, antibacterial therapeutics, bacterial biofilms, physicochemical properties, antibiotic resistance
MeSH terms: Anti-Bacterial Agents, Humans, Liposomes, Molecular Weight, Nitrates, Nitric Oxide, Polymers, Surface Properties, Biofilms, Nitric Oxide Donors, Macromolecular Substances, Nanoparticles

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Nitric Oxide–Releasing Macromolecular Scaffolds for Antibacterial Applications

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