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Controlled PEGylation of Monodisperse Fe3O4 Nanoparticles for Reduced Non‐Specific Uptake by Macrophage Cells

Xie, J., Xu, C., Kohler, N., Hou, Y., Sun, S.·2007·Advanced Materials

Abstract

A dopamine-PEG based ligand is synthesized and used to stabilize monodisperse 9 nm Fe3O4 nanoparticles in physiological conditions and against non-specific uptake by macrophage cells. Such stable nanoparticles can be used to enhance the efficiency in target-specific drug delivery and to increase the signal-to-noise ratio in magnetic resonance imaging (MRI).

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Crossref · 10.1002/adma.200701975

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Metadata

Authors
Xie, J., Xu, C., Kohler, N., Hou, Y., & Sun, S.
Venue
Advanced Materials
Publisher
Wiley
Published
2007-10-17
Volume
19
Issue
20
Pages
3163-3166
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W2064636526
Cited by
686
References
0
FWCI
12.37
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.