The DOI matches its Crossref record; 194 of the 194 references it cites were found in a registry or an index.
Polymeric Materials for Gene Delivery and DNA Vaccination
Open accessAbstract
Gene delivery holds great potential for the treatment of many different diseases. Vaccination with DNA holds particular promise, and may provide a solution to many technical challenges that hinder traditional vaccine systems including rapid development and production and induction of robust cell‐mediated immune responses. However, few candidate DNA vaccines have progressed past preclinical development and none have been approved for human use. This Review focuses on the recent progress and challenges facing materials design for nonviral DNA vaccine drug delivery systems. In particular, we highlight work on new polymeric materials and their effects on protective immune activation, gene delivery, and current efforts to optimize polymeric delivery systems for DNA vaccination.
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Cites
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Cited by
A materials-science perspective on tackling COVID-19
Tang, Z., Kong, N., Zhang, X., Liu, Y., Hu, P., Mou, S., Liljeström, P., Shi, J., Tan, W., Kim, J. S., et al. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-00247-y · Cited by 303
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Metadata
- Authors
- Nguyen, D. N., Green, J. J., Chan, J. M., Langer, R., & Anderson, D. G.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2009-02-19
- Volume
- 21
- Issue
- 8
- Pages
- 847-867
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W1987811891
- Cited by
- 273
- References
- 194
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- green
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- Nguyen, D. N., Green, J. J., Chan, J. M., Langer, R., & Anderson, D. G. (2009). Polymeric Materials for Gene Delivery and DNA Vaccination. Advanced Materials. https://doi.org/10.1002/adma.200801478
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
