The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Cancer Nanotheranostics: Improving Imaging and Therapy by Targeted Delivery Across Biological Barriers
Open accessAbstract
Cancer nanotheranostics aims to combine imaging and therapy of cancer through use of nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the molecular level can significantly improve the effectiveness and specificity of therapy to cancers that are currently difficult to treat. In particular, metastatic cancers, drug‐resistant cancers, and cancer stem cells impose the greatest therapeutic challenge for targeted therapy. Targeted therapy can be achieved with appropriately designed drug delivery vehicles such as nanoparticles, adult stem cells, or T cells in immunotherapy. In this article, we first review the different types of nanotheranostic particles and their use in imaging, followed by the biological barriers they must bypass to reach the target cancer cells, including the blood, liver, kidneys, spleen, and particularly the blood‐brain barrier. We then review how nanotheranostics can be used to improve targeted delivery and treatment of cancer cells. Finally, we discuss development of nanoparticles to overcome current limitations in cancer therapy.
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Cites
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Cited by
Ge, Z., & Liu, S. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60048c · Cited by 914
Yao, C., Wang, W., Wang, P., Zhao, M., Li, X., & Zhang, F. (2018) · Advanced Materials · doi:10.1002/adma.201704833 · Cited by 447
Skin cancer and new treatment perspectives: A review
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Huang, C.-C., Chia, W.-T., Chung, M.-F., Lin, K.-J., Hsiao, C.-W., Jin, C., Lim, W.-H., Chen, C.-C., & Sung, H.-W. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b01784 · Cited by 372
Choi, K. Y., Han, H. S., Lee, E. S., Shin, J. M., Almquist, B. D., Lee, D. S., & Park, J. H. (2019) · Advanced Materials · doi:10.1002/adma.201803549 · Cited by 319
Metadata
- Authors
- Kievit, F. M., & Zhang, M.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2011-08-15
- Volume
- 23
- Issue
- 36
- Pages
- H217-47
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2112511163
- Cited by
- 496
- References
- 29
- FWCI
- 24.25
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
