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A Sensitive H2O2 Assay Based on Dumbbell‐like PtPd‐Fe3O4 Nanoparticles
Abstract
Dumbbell-like Pt(48)Pd(52)-Fe(3)O(4) nanoparticles are synthesized and functionalized with oleylamine-polyethyleneglycol to serve as an efficient catalyst for H(2)O(2) reduction and tetramethylbenzidine (TMB) oxidation in biological solutions. The Pt(48)Pd(52)-Fe(3)O(4)/TMB kit is even more active than the natural enzyme for H(2)O(2) detection with a detection limit reaching 2 μM, and is successfully used to quantitatively monitor the extracellular H(2)O(2) generated by neutrophils.
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Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Oxidative stress and aberrant signaling in aging and cognitive decline
Dröge, W., & Schipper, H. M. (2007) · Aging Cell · doi:10.1111/j.1474-9726.2007.00294.x · Cited by 479
Cited by
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Wei, H., & Wang, E. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35486e · Cited by 3,779
Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes
Lin, Y., Ren, J., & Qu, X. (2014) · Accounts of Chemical Research · doi:10.1021/ar400250z · Cited by 1,252
Tao, Y., Ju, E., Ren, J., & Qu, X. (2015) · Advanced Materials · doi:10.1002/adma.201405105 · Cited by 620
Organic Phase Syntheses of Magnetic Nanoparticles and Their Applications
Wu, L., Mendoza-Garcia, A., Li, Q., & Sun, S. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00687 · Cited by 601
Self-citationMorphology-dependent nanocatalysts: Rod-shaped oxides
Li, Y., & Shen, W. (2014) · Chem. Soc. Rev. · doi:10.1039/c3cs60296f · Cited by 531
Metadata
- Authors
- Sun, X., Guo, S., Chung, C., Zhu, W., & Sun, S.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2012-10-12
- Volume
- 25
- Issue
- 1
- Pages
- 132-136
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2025549169
- Cited by
- 215
- References
- 2
- FWCI
- 7.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sun, X., Guo, S., Chung, C., Zhu, W., & Sun, S. (2013). A Sensitive H2O2 Assay Based on Dumbbell‐like PtPd‐Fe3O4 Nanoparticles. Advanced Materials. https://doi.org/10.1002/adma.201203218
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