The DOI matches its Crossref record; 145 of the 145 references it cites were found in a registry or an index.
Smart Drug Delivery Nanocarriers with Self‐Assembled DNA Nanostructures
Abstract
Self‐assembled DNA nanostructures have emerged as a type of nano‐biomaterials with precise structures, versatile functions and numerous applications. One particularly promising application of these DNA nanostructures is to develop universal nanocarriers for smart and targeted drug delivery. DNA is the genetic material in nature, and inherently biocompatible. Nevertheless, cell membranes are barely permeable to naked DNA molecules, either single‐ or double‐ stranded; transport across the cell membrane is only possible with the assistance of transfection agents. Interestingly, recent studies revealed that many DNA nanostructures could readily go into cells with high cell uptake efficiency. In this Progress Report, we will review recent advances on using various DNA nanostructures, e.g., DNA nanotubes, DNA tetrahedra, and DNA origami nanorobot, as drug delivery nanocarriers, and demonstrate several examples aiming at therapeutic applications with CpG‐based immunostimulatory and siRNA‐based gene silencing oligonucleotides.
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Cites
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Supramolecular cancer nanotheranostics
Zhou, J., Rao, L., Yu, G., Cook, T. R., Chen, X., & Huang, F. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00011f · Cited by 411
Han, X., Jiang, Y., Li, S., Zhang, Y., Ma, X., Wu, Z., Wu, Z., & Qi, X. (2019) · Nanoscale · doi:10.1039/c8nr05546g · Cited by 77
Nanomedicine-based combination anticancer therapy between nucleic acids and small-molecular drugs
Huang, W., Chen, L., Kang, L., Jin, M., Sun, P., Xin, X., Gao, Z., & Bae, Y. H. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.06.004 · Cited by 77
Metadata
- Authors
- Li, J., Fan, C., Pei, H., Shi, J., & Huang, Q.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2013-06-13
- Volume
- 25
- Issue
- 32
- Pages
- 4386-4396
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W1986162845
- Cited by
- 441
- References
- 145
- FWCI
- 10.76
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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