The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Reduction and pH Dual‐Sensitive Polymeric Vector for Long‐Circulating and Tumor‐Targeted siRNA Delivery
Abstract
A novel reduction and pH dual-sensitive nonviral vector for long-circulating and tumor-targeted siRNA delivery is described. The nanomedicine is negatively charged at neutral pH of bloodstream whereas it is positively charged at lower pH of tumor tissue (ca. 6.8). Interlayer crosslinking with disulfide bonds stabilizes the nanomedicine during blood circulation and allows quick intracellular siRNA release after endocytosis.
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Cites
Factors affecting the clearance and biodistribution of polymeric nanoparticles
Alexis, F., Pridgen, E., Molnar, L. K., & Farokhzad, O. C. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800051m · Cited by 3,699
Layer-by-Layer Nanoparticles with a pH-Sheddable Layer for in Vivo Targeting of Tumor Hypoxia
Poon, Z., Chang, D., Zhao, X., & Hammond, P. T. (2011) · ACS Nano · doi:10.1021/nn200876f · Cited by 343
Cited by
siRNA Delivery Strategies: A Comprehensive Review of Recent Developments
Tatiparti, K., Sau, S., Kashaw, S., & Iyer, A. (2017) · Nanomaterials · doi:10.3390/nano7040077 · Cited by 429
The acidic tumor microenvironment: a target for smart cancer nano-theranostics
Feng, L., Dong, Z., Tao, D., Zhang, Y., & Liu, Z. (2018) · National Science Review · doi:10.1093/nsr/nwx062 · Cited by 426
Sequentially Responsive Shell‐Stacked Nanoparticles for Deep Penetration into Solid Tumors
Chen, J., Ding, J., Wang, Y., Cheng, J., Ji, S., Zhuang, X., & Chen, X. (2017) · Advanced Materials · doi:10.1002/adma.201701170 · Cited by 420
Self-citationFusogenic Reactive Oxygen Species Triggered Charge‐Reversal Vector for Effective Gene Delivery
Liu, X., Xiang, J., Zhu, D., Jiang, L., Zhou, Z., Tang, J., Liu, X., Huang, Y., & Shen, Y. (2016) · Advanced Materials · doi:10.1002/adma.201504288 · Cited by 353
Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery
Kim, B., Park, J., & Sailor, M. J. (2019) · Advanced Materials · doi:10.1002/adma.201903637 · Cited by 298
Metadata
- Authors
- Li, J., Yu, X., Wang, Y., Yuan, Y., Xiao, H., Cheng, D., & Shuai, X.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2014-10-31
- Volume
- 26
- Issue
- 48
- Pages
- 8217-8224
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W1975603353
- Cited by
- 215
- References
- 2
- FWCI
- 9.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, J., Yu, X., Wang, Y., Yuan, Y., Xiao, H., Cheng, D., & Shuai, X. (2014). A Reduction and pH Dual‐Sensitive Polymeric Vector for Long‐Circulating and Tumor‐Targeted siRNA Delivery. Advanced Materials. https://doi.org/10.1002/adma.201403877
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