The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Fusogenic Reactive Oxygen Species Triggered Charge‐Reversal Vector for Effective Gene Delivery
Abstract
A novel fusogenic lipidic polyplex (FLPP) vector is designed to fuse with cell membranes, mimicking viropexis, and eject the polyplex into the cytosol, where the cationic polymer is subsequently oxidized by intracellular reactive oxygen species and converts to being negatively charged, efficiently releasing the DNA. The vector delivering suicide gene achieves significantly better inhibition of tumor growth than doxorubicin.
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Cites
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
Farmer, H., McCabe, N., Lord, C. J., Tutt, A. N. J., Johnson, D. A., Richardson, T. B., Santarosa, M., Dillon, K. J., Hickson, I., Knights, C., et al. (2005) · Nature · doi:10.1038/nature03445 · Cited by 6,683
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Trachootham, D., Alexandre, J., & Huang, P. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2803 · Cited by 5,452
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
Naldini, L., Blömer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., & Trono, D. (1996) · Science · doi:10.1126/science.272.5259.263 · Cited by 4,903
Non-viral vectors for gene-based therapy
Yin, H., Kanasty, R. L., Eltoukhy, A. A., Vegas, A. J., Dorkin, J. R., & Anderson, D. G. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3763 · Cited by 3,123
Nonviral vectors for gene delivery
Mintzer, M. A., & Simanek, E. E. (2009) · Chemical Reviews · doi:10.1021/cr800409e · Cited by 2,366
Delivery materials for siRNA therapeutics
Kanasty, R., Dorkin, J. R., Vegas, A., & Anderson, D. (2013) · Nature Materials · doi:10.1038/nmat3765 · Cited by 1,800
PEGylated nanoparticles for biological and pharmaceutical applications
Otsuka, H., Nagasaki, Y., & Kataoka, K. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00226-0 · Cited by 1,588
Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid
Zabner, J., Fasbender, A. J., Moninger, T., Poellinger, K. A., & Welsh, M. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.32.18997 · Cited by 1,410
Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors
Sugahara, K. N., Teesalu, T., Karmali, P. P., Kotamraju, V. R., Agemy, L., Girard, O. M., Hanahan, D., Mattrey, R. F., & Ruoslahti, E. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.10.013 · Cited by 1,136
Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs
Sugahara, K. N., Teesalu, T., Karmali, P. P., Kotamraju, V. R., Agemy, L., Greenwald, D. R., & Ruoslahti, E. (2010) · Science · doi:10.1126/science.1183057 · Cited by 1,075
Cited by
Lin, T., Zhao, P., Jiang, Y., Tang, Y., Jin, H., Pan, Z., He, H., Yang, V. C., & Huang, Y. (2016) · ACS Nano · doi:10.1021/acsnano.6b04268 · Cited by 527
Self-citationDendrimer-based drug delivery systems: history, challenges, and latest developments
Wang, J., Li, B., Qiu, L., Qiao, X., & Yang, H. (2022) · Journal of Biological Engineering · doi:10.1186/s13036-022-00298-5 · Cited by 406
Core–Shell Microneedle Gel for Self-Regulated Insulin Delivery
Wang, J., Ye, Y., Yu, J., Kahkoska, A. R., Zhang, X., Wang, C., Sun, W., Corder, R. D., Chen, Z., Khan, S. A., et al. (2018) · ACS Nano · doi:10.1021/acsnano.7b08152 · Cited by 299
Leveraging Physiology for Precision Drug Delivery
Sun, W., Hu, Q., Ji, W., Wright, G., & Gu, Z. (2017) · Physiological Reviews · doi:10.1152/physrev.00015.2016 · Cited by 169
Li, J., Peng, H., Zhang, W., Li, M., Wang, N., Peng, C., Zhang, X., & Li, Y. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c08756 · Cited by 43
Metadata
- Authors
- Liu, X., Xiang, J., Zhu, D., Jiang, L., Zhou, Z., Tang, J., Liu, X., Huang, Y., & Shen, Y.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2015-12-14
- Volume
- 28
- Issue
- 9
- Pages
- 1743-1752
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2215236428
- Cited by
- 353
- References
- 77
- FWCI
- 14.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Liu, X., Xiang, J., Zhu, D., Jiang, L., Zhou, Z., Tang, J., Liu, X., Huang, Y., & Shen, Y. (2016). Fusogenic Reactive Oxygen Species Triggered Charge‐Reversal Vector for Effective Gene Delivery. Advanced Materials. https://doi.org/10.1002/adma.201504288
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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