The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Paintable and Rapidly Bondable Conductive Hydrogels as Therapeutic Cardiac Patches
Abstract
In recent years, cardiac patches have been developed for the treatment of myocardial infarction. However, the fixation approaches onto the tissue through suture or phototriggered reaction inevitably cause new tissue damage. Herein, a paintable hydrogel is constructed based on Fe 3+‐triggered simultaneous polymerization of covalently linked pyrrole and dopamine in the hyperbranched chains where the in situ formed conductive polypyrrole also uniquely serves to crosslink network. This conductive and adhesive hydrogel can be conveniently painted as a patch onto the heart surface without adverse liquid leakage. The functional patch whose conductivity is equivalent to that of normal myocardium is strongly bonded to the beating heart within 4 weeks, accordingly efficiently boosting the transmission of electrophysiological signals. Eventually, the reconstruction of cardiac function and revascularization of the infarct myocardium are remarkably improved. The translatable suture‐free strategy reported in this work is promising to address the human clinical challenges in cardiac tissue engineering.
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Tough adhesives for diverse wet surfaces
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Tough bonding of hydrogels to diverse non-porous surfaces
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Nanoparticle solutions as adhesives for gels and biological tissues
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Self-citationDarabi, M. A., Khosrozadeh, A., Mbeleck, R., Liu, Y., Chang, Q., Jiang, J., Cai, J., Wang, Q., Luo, G., & Xing, M. (2017) · Advanced Materials · doi:10.1002/adma.201700533 · Cited by 672
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Cited by
Yuk, H., Lu, B., & Zhao, X. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00595h · Cited by 2,108
Nam, S., & Mooney, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00798 · Cited by 764
Hydrogels and Their Applications in Targeted Drug Delivery
Narayanaswamy, R., & Torchilin, V. P. (2019) · Molecules · doi:10.3390/molecules24030603 · Cited by 664
Mussel-inspired hydrogels: From design principles to promising applications
Zhang, C., Wu, B., Zhou, Y., Zhou, F., Liu, W., & Wang, Z. (2020) · Chemical Society Reviews · doi:10.1039/c9cs00849g · Cited by 653
Self-citationHighly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing
Yang, Z., Huang, R., Zheng, B., Guo, W., Li, C., He, W., Wei, Y., Du, Y., Wang, H., Wu, D., et al. (2021) · Advanced Science · doi:10.1002/advs.202003627 · Cited by 609
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Metadata
- Authors
- Liang, S., Zhang, Y., Wang, H., Xu, Z., Chen, J., Bao, R., Tan, B., Cui, Y., Fan, G., Wang, W., Wang, W., & Liu, W.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2018-04-24
- Volume
- 30
- Issue
- 23
- Pages
- e1704235-e1704235
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2800098787
- Cited by
- 458
- References
- 34
- FWCI
- 40.06
- Type
- journal article
- Language
- en
- Open access
- closed
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- Liang, S., Zhang, Y., Wang, H., Xu, Z., Chen, J., Bao, R., Tan, B., Cui, Y., Fan, G., Wang, W., Wang, W., & Liu, W. (2018). Paintable and Rapidly Bondable Conductive Hydrogels as Therapeutic Cardiac Patches. Advanced Materials. https://doi.org/10.1002/adma.201704235
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