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Cited by 609

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing

Open access
Yang, Zifeng, Huang, Rongkang, Zheng, Bingna, Guo, Wentai, Li, Chuangkun, He, Wenyi, Wei, Yingqi, Du, Yang, Wang, Huaiming, Wu, Dingcai, Wang, Hui·2021·Advanced Science

Abstract

Treatment of wounds in special areas is challenging due to inevitable movements and difficult fixation. Common cotton gauze suffers from incomplete joint surface coverage, confinement of joint movement, lack of antibacterial function, and frequent replacements. Hydrogels have been considered as good candidates for wound dressing because of their good flexibility and biocompatibility. Nevertheless, the adhesive, mechanical, and antibacterial properties of conventional hydrogels are not satisfactory. Herein, cationic polyelectrolyte brushes grafted from bacterial cellulose (BC) nanofibers are introduced into polydopamine/polyacrylamide hydrogels. The 1D polymer brushes have rigid BC backbones to enhance mechanical property of hydrogels, realizing high tensile strength (21–51 kPa), large tensile strain (899–1047%), and ideal compressive property. Positively charged quaternary ammonium groups of tethered polymer brushes provide long‐lasting antibacterial property to hydrogels and promote crawling and proliferation of negatively charged epidermis cells. Moreover, the hydrogels are rich in catechol groups and capable of adhering to various surfaces, meeting adhesive demand of large movement for special areas. With the above merits, the hydrogels demonstrate less inflammatory response and faster healing speed for in vivo wound healing on rats. Therefore, the multifunctional hydrogels show stable covering, little displacement, long‐lasting antibacteria, and fast wound healing, demonstrating promise in wound dressing.

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Metadata

Authors
Yang, Z., Huang, R., Zheng, B., Guo, W., Li, C., He, W., Wei, Y., Du, Y., Wang, H., Wu, D., & Wang, H.
Venue
Advanced Science
Publisher
Wiley
Published
2021-03-05
Volume
8
Issue
8
Pages
2003627-2003627
ISSN
2198-3844 (ISSN-L)
OpenAlex
W3135081402
Cited by
609
References
52
FWCI
43.70
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing. https://app.cochat.ai/papers/10.1002/advs.202003627
The paper
Yang, Z., Huang, R., Zheng, B., Guo, W., Li, C., He, W., Wei, Y., Du, Y., Wang, H., Wu, D., & Wang, H. (2021). Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing. Advanced Science. https://doi.org/10.1002/advs.202003627

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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