The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Manganese‐Dioxide‐Coating‐Instructed Plasmonic Modulation of Gold Nanorods for Activatable Duplex‐Imaging‐Guided NIR‐II Photothermal‐Chemodynamic Therapy
Abstract
Nanotheranostic agents of gold nanomaterials in the second near‐infrared (NIR‐II) window have attracted significant attention in cancer management, owing to the reduced background signal and deeper penetration depth in tissues. However, it is still challenging to modulate the localized surface plasmon resonance (LSPR) of gold nanomaterials from the first near‐infrared (NIR‐I) to NIR‐II region. Herein, a plasmonic modulation strategy of gold nanorods (GNRs) through manganese dioxide coating is developed for NIR‐II photoacoustic/magnetic resonance (MR) duplex‐imaging‐guided NIR‐II photothermal chemodynamic therapy. GNRs are coated with silica dioxide (SiO 2) and then covered with magnesium dioxide (MnO 2) to obtain the final product of GNR@SiO 2@MnO 2 (denoted as GSM). The LSPR peak of GNRs could be tuned by adjusting the thickness of the MnO 2 layer. Theoretical simulations reveal that this plasmonic modulation is mainly due to the change of refraction index around the GNRs after coating with the MnO 2 layer. Additionally, the MnO 2 layer is demonstrated to degrade into Mn 2+ ions in response to peroxide and acidic protons in the tumor microenvironment, which allows for MR imaging and chemodynamic therapy. This plasmonic modulation strategy can be adapted to other metal nanomaterials and the construction of a new class of NIR‐II nanotheranostics.
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Cites
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Strategies for enhancing cancer chemodynamic therapy performance
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Metadata
- Authors
- He, T., Jiang, C., He, J., Zhang, Y., He, G., Wu, J., Lin, J., Zhou, X., & Huang, P.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2021-03
- Volume
- 33
- Issue
- 13
- Pages
- e2008540-e2008540
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W3133785598
- Cited by
- 304
- References
- 34
- FWCI
- 17.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- He, T., Jiang, C., He, J., Zhang, Y., He, G., Wu, J., Lin, J., Zhou, X., & Huang, P. (2021). Manganese‐Dioxide‐Coating‐Instructed Plasmonic Modulation of Gold Nanorods for Activatable Duplex‐Imaging‐Guided NIR‐II Photothermal‐Chemodynamic Therapy. Advanced Materials. https://doi.org/10.1002/adma.202008540
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