The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Mobile Microrobots for Active Therapeutic Delivery
Open accessAbstract
Recent advances in the versatility and sophistication of design, fabrication, and control methods of mobile microrobots could have a transforming impact on future healthcare technologies. Self‐propelled or remotely actuated, synthetic, or biohybrid microrobots can navigate to difficult‐to‐reach regions in the human body to deliver therapeutics for microscopically localized medical interventions. Here, recent progress in the design of microrobotic systems concerning therapeutic delivery of drugs, cells, and genetic materials is reported. This perspective prioritizes the design aspects of microrobots for medical cargo loading, navigation in biologically relevant environments, and controlled cargo release. In the final section, future prospects and a discussion on the critical shortcomings for the benchside‐to‐bedside translation of medical microrobots are provided.
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Cites
Neutrophil recruitment and function in health and inflammation
Kolaczkowska, E., & Kubes, P. (2013) · Nature Reviews Immunology · doi:10.1038/nri3399 · Cited by 5,472
Doxil® — The first FDA-approved nano-drug: Lessons learned
Barenholz, Y. (. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.020 · Cited by 4,792
Innate and adaptive immune cells in the tumor microenvironment
Gajewski, T. F., Schreiber, H., & Fu, Y.-X. (2013) · Nature Immunology · doi:10.1038/ni.2703 · Cited by 4,148
Overcoming the challenges in administering biopharmaceuticals: Formulation and delivery strategies
Mitragotri, S., Burke, P. A., & Langer, R. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4363 · Cited by 1,702
Rasala, B. A., & Mayfield, S. P. (2011) · Bioengineered Bugs · doi:10.4161/bbug.2.1.13423 · Cited by 122
Targeting cancer cells via tumor-homing peptide CREKA functional PEG nanoparticles
Okur, A. C., Erkoc, P., & Kizilel, S. (2016) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2016.08.005 · Cited by 60
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Cited by
3D printing of functional microrobots
Li, J., & Pumera, M. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01062f · Cited by 303
Akolpoglu, M. B., Alapan, Y., Dogan, N. O., Baltaci, S. F., Yasa, O., Aybar Tural, G., & Sitti, M. (2022) · Science Advances · doi:10.1126/sciadv.abo6163 · Cited by 293
Self-citationDong, X., & Sitti, M. (2020) · The International Journal of Robotics Research · doi:10.1177/0278364920903107 · Cited by 198
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Metadata
- Authors
- Erkoc, P., Yasa, I. C., Ceylan, H., Yasa, O., Alapan, Y., & Sitti, M.
- Venue
- Advanced Therapeutics
- Publisher
- Wiley
- Published
- 2018-10-10
- Volume
- 2
- Issue
- 1
- ISSN
- 2366-3987 (ISSN-L)
- OpenAlex
- W2897012346
- Cited by
- 230
- References
- 6
- FWCI
- 13.58
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Erkoc, P., Yasa, I. C., Ceylan, H., Yasa, O., Alapan, Y., & Sitti, M. (2019). Mobile Microrobots for Active Therapeutic Delivery. Advanced Therapeutics. https://doi.org/10.1002/adtp.201800064
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