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Transdermal drug delivery

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Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

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Polymers for the sustained release of proteins and other macromolecules

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Large Porous Particles for Pulmonary Drug Delivery

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Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

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Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

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Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

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Nanoparticle vaccines

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Polysorbates 20 and 80 Used in the Formulation of Protein Biotherapeutics: Structure and Degradation Pathways

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Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

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Direct inhibition of the NOTCH transcription factor complex

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Therapeutic cell engineering with surface-conjugated synthetic nanoparticles

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State of the art in PEGylation: The great versatility achieved after forty years of research

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Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent

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Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer

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Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

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Enhanced antibody half-life improves in vivo activity

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A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

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Investigating the Impact of Nanoparticle Size on Active and Passive Tumor Targeting Efficiency

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Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation

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Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle

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Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide)

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Biodegradable block copolymers for delivery of proteins and water-insoluble drugs

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Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo

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Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding

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Is the oral route possible for peptide and protein drug delivery?

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Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy

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Albumin as a versatile platform for drug half-life extension

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A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture

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A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner

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Improving protein therapeutics with sustained-release formulations

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Perfused multiwell plate for 3D liver tissue engineering

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First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip

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Reversible Self-Association Increases the Viscosity of a Concentrated Monoclonal Antibody in Aqueous Solution

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Darbepoetin alfa has a longer circulating half-life and greater in vivo potency than recombinant human erythropoietin

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Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

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Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery

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A Stapled BID BH3 Helix Directly Binds and Activates BAX

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Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B

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Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR

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Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

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Formulation and delivery issues for monoclonal antibody therapeutics

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Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models

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Effect of Dextran on Protein Stability and Conformation Attributed to Macromolecular Crowding

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Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis

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Targeted gene knockout by direct delivery of zinc-finger nuclease proteins

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Antitumor Activity of a Novel Bispecific Antibody That Targets the ErbB2/ErbB3 Oncogenic Unit and Inhibits Heregulin-Induced Activation of ErbB3

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A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo

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RNAi Therapies: Drugging the Undruggable

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Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

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Factors Affecting the Viscosity in High Concentration Solutions of Different Monoclonal Antibodies

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Protein Instability and Immunogenicity: Roadblocks to Clinical Application of Injectable Protein Delivery Systems for Sustained Release

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Transdermal protein delivery by a coadministered peptide identified via phage display

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Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: The effect of cholate type, particle size and administered dose

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Encapsulation of Exenatide in Poly-( d,l -Lactide-Co-Glycolide) Microspheres Produced an Investigational Long-Acting Once-Weekly Formulation for Type 2 Diabetes

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Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates

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Production and Implantation of Renal Extracellular Matrix Scaffolds From Porcine Kidneys as a Platform for Renal Bioengineering Investigations

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Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic

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Electrochemically deposited metal nanoparticles for enhancing the performance of microfluidic MEMS in biochemical analysis

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Unsafe injections in low-income country health settings: need for injection safety promotion to prevent the spread of blood-borne viruses

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Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer

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Potent Delivery of Functional Proteins into Mammalian Cells in Vitro and in Vivo Using a Supercharged Protein

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Advances in Polymeric Systems for Tissue Engineering and Biomedical Applications

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Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

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Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4)

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Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats

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Observation of Small Cluster Formation in Concentrated Monoclonal Antibody Solutions and Its Implications to Solution Viscosity

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Micro and Nanoparticle‐Based Delivery Systems for Vaccine Immunotherapy: An Immunological and Materials Perspective

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