Bioenergetic approaches for neuroprotection in Parkinson's disease

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Items 101–200 of 235

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2. Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson’s Disease
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3. L-carnitine prevents memory impairment induced by chronic REM-sleep deprivation
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4. Mitochondrial Metabolism Modulation: A New Therapeutic Approach for Parkinsons Disease
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5. Diapocynin prevents early Parkinson's disease symptoms in the leucine-rich repeat kinase 2 (LRRK2R1441G) transgenic mouse
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6. Targeting cellular energy production in neurological disorders
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7. Stimulation of H2O2 generation by calcium in brain mitochondria respiring on α‐glycerophosphate
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8. Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression.
   F. J. Fernandez-Gomez, M. Pastor, E. García-Martínez, R. M. D. de Mera, M. Gou-Fàbregas, M. Gomez-Lazaro, S. Calvo, R. Soler, M. Galindo, J. Jordán · 2006 · Neurobiology of Disease
9. The MPTP marmoset model of Parkinsonism: a multi-purpose non-human primate model for neurodegenerative diseases
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10. L-carnitine and Co Q10 ameliorate potassium dichromate -induced acute brain injury in rats targeting AMPK/AKT/NF-κβ
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11. Bioenergetic‐based neuroprotection and glaucoma
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12. Medical Management of Parkinsons Disease: Focus on Neuroprotection
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13. Therapeutic Strategies Targeting Mitochondrial Calcium Signaling: A New Hope for Neurological Diseases?
    Laura R. Rodríguez, Tamara Lapeña-Luzón, Noelia Benetó, Vicent Beltran-Beltran, Federico Vicente Pallardó, Pilar González‐Cabo, Juan A. Navarro · 2022 · Antioxidants
14. Mitochondrial Targeted Antioxidant in Cerebral Ischemia
    Ahmed, Ejaz, Donovan, Tucker, Yujiao, Lu, Zhang, Quanguang · 2015 · Journal of Neurology and Neuroscience
15. Carnitine reduces the lipoperoxidative damage of the membrane and apoptosis after induction of cell stress in experimental glaucoma
    Nicola Calandrella, C De Seta, Gianfranco Scarsella, Gianfranco Risuleo · 2010 · Cell Death and Disease
16. Toward prevention of alzheimers disease – Potential nutraceutical strategies for suppressing the production of amyloid beta peptides
    Mark Frederick McCarty · 2006 · Medical Hypotheses
17. Pharmacological Therapy in Parkinson's Disease: Focus on Neuroprotection
    Zsigmond Tamás Kincses, László Vécsei · 2010 · CNS Neuroscience & Therapeutics
18. Links between Nutrition, Drug Abuse, and the Metabolic Syndrome
    Ashraf Virmani, ZBIGNIEW K. BINIENDA, Syed F. Ali, Franco Gaetani · 2006 · Annals of the New York Academy of Sciences
19. The Bidirectional Interplay of α-Synuclein with Lipids in the Central Nervous System and Its Implications for the Pathogenesis of Parkinson’s Disease
    Kristina Battis, Wei Xiang, Jürgen Winkler · 2023 · International Journal of Molecular Sciences
20. Branched chain amino acids supplemented with L-acetylcarnitine versus BCAA treatment in hepatic coma: a randomized and controlled double blind study
    Mariano Malaguarnera, Corrado Risino, Lisa Cammalleri, Lucia Malaguarnera, Marinella Astuto, Ignazio Vecchio, Liborio Rampello · 2009 · European Journal of Gastroenterology & Hepatology
21. Neuroprotection in parkinson’s disease: An elusive goal
    William C. Koller, Maria Graciela Cersosimo · 2004 · Current Neurology and Neuroscience Reports
22. A metabolic biomarker predicts Parkinson’s disease at the early stages in patients and animal models
    David Mallet, Thibault Dufourd, Mélina Decourt, Carole Carcenac, Paola Bossù, Laure Verlin, Pierre‐Olivier Fernagut, Marianne Benoit‐Marand, Gianfranco Spalletta, Emmanuel Barbier et al. · 2021 · Journal of Clinical Investigation
23. Recent developments in the pharmacological treatment of Parkinson?s disease
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24. Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish
    Bonnie L. Robinson, Melanie Dumas, Elvis Cuevas, Qiang Gu, Merle G. Paule, Syed F. Ali, Jyotshna Kanungo · 2016 · Neurotoxicology and Teratology
25. Oxidative Stress, Neuroinflammation, and Neurodegeneration
    Hui‐Ming Gao, Hui Zhou, Jau‐Shyong Hong · 2014 · Springer eBooks
26. Inhibition of cytosolic and mitochondrial creatine kinase by siRNA in HaCaT- and HeLaS3-cells affects cell viability and mitochondrial morphology
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27. Acetyl-l-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism
    Vincenza Bagetta, Ilaria Barone, Veronica Ghiglieri, Massimiliano Di Filippo, Carmelo Sgobio, Giorgio Bernardi, Paolo Calabresi, Barbara Picconi · 2008 · Neuropharmacology
28. Oral creatine supplementation attenuates L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats
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29. Next generation antidepressants
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30. Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model
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31. Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia
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32. In the Rat Brain Acetyl-l-carnitine Treatment Modulates the Expression of Genes Involved in Neuronal Ceroid Lipofuscinosis
    Giovanna Traina, Rodolfo Bernardi, Enrico Cataldo, Monica Macchi, Mauro Durante, Marcello Brunelli · 2008 · Molecular Neurobiology
33. Detection of fortification of ginkgo products using nanoelectrospray ionization mass spectrometry
    Changqing Liu, Rupasri Mandal, Xing‐Fang Li · 2005 · The Analyst
34. Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease
    Satinder Kaur, Abhishek Sehrawat, Sarabjit Singh Mastana, Ramesh J. L. Kandimalla, Pushpender Kumar Sharma, Gurjit Kaur Bhatti, Jasvinder Singh Bhatti · 2023 · Life Sciences
35. Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction
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36. Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
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37. A metabolic biomarker predicts Parkinson’s disease at the early stages in patients and animal models
    David Mallet, Thibault Dufourd, Mélina Decourt, Carole Carcenac, Paola Bossù, Laure Verlin, Pierre‐Olivier Fernagut, Marianne Benoit‐Marand, Gianfranco Spalletta, Emmanuel Barbier et al. · 2022 · DOAJ (DOAJ: Directory of Open Access Journals)
38. Silencing of FABP3 promotes apoptosis and induces mitochondrion impairment in embryonic carcinoma cells
    Yahui Shen, Guixian Song, Yao-Qiu Liu, Wei Yue Sun, Lijuan Zhou, HAI-LANG LIU, Rong Yang, Yanhui Sheng, Lingmei Qian, Xiangqing Kong · 2012 · Journal of Bioenergetics and Biomembranes
39. Current management of Parkinson′s disease
    FK Salawu, Abdulfatai Bamidele Olokoba, Ali Danburam · 2010 · Annals of African Medicine
40. Mitochondria: Prospective Targets for Neuroprotection in Parkinson’s Disease
    Anuradha Yadav, Swati Agarwal, Shashi Kant Tiwari, Rajnish Kumar Chaturvedi · 2014 · Current Pharmaceutical Design
41. Gateways for Glutamate Neuroprotection in Parkinson’s Disease (PD): Essential Role of EAAT3 and NCX1 Revealed in an In Vitro Model of PD
    Silvia Piccirillo, Simona Magi, Alessandra Preziuso, Pasqualina Castaldo, Salvatore Amoroso, Vincenzo Lariccia · 2020 · Cells
42. The role of α-synuclein in neurodegeneration — An update
    K. A. Jellinger · 2012 · Translational Neuroscience
43. Opposing effects of ketamine and acetyl l-carnitine on the serotonergic system of zebrafish
    Bonnie L. Robinson, Melanie Dumas, Merle G. Paule, Syed F. Ali, Jyotshna Kanungo · 2015 · Neuroscience Letters
44. Beneficial Effects of a Q-ter® Based Nutritional Mixture on Functional Performance, Mitochondrial Function, and Oxidative Stress in Rats
    Jinze Xu, Arnold Young Seo, Darya A. Vorobyeva, Christy S. Carter, Stephen Douglas Anton, Angela Maria Serena Lezza, Christiaan Leeuwenburgh · 2010 · PLoS ONE
45. Effect of intraperitoneal acetyl-L-carnitine (ALCAR) on anxiety-like behaviours in rats
    Joseph Levine, Zeev Kaplan, Jay W. Pettegrew, Richard J. McClure, Samuel Gershon, Igor Buriakovsky, Hagit Cohen · 2005 · The International Journal of Neuropsychopharmacology
46. A Creatine Transporter Is Operative at the Brush Border Level of the Rat Jejunal Enterocyte
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47. Current and future treatments in progressive supranuclear palsy
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48. Literature-Related Discovery (LRD)
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49. Effect of ginsenoside‑Rg1 on experimental Parkinson's disease: A systematic review and meta‑analysis of animal studies
    Yibo He, Yonglin Liu, Zheng-Dong Yang, Jiahong Lu, Yao Hua Song, Yan-Ming Guan, Yi-Min Chen · 2021 · Experimental and Therapeutic Medicine
50. Effect of Simvastatin, Coenzyme Q10, Resveratrol, Acetylcysteine and Acetylcarnitine on Mitochondrial Respiration
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51. Targeted upregulation of uncoupling protein 2 within the basal ganglia output structure ameliorates dyskinesia after severe liver failure
    Yunhu Bai, Yang Bai, Shengming Wang, Feifei Wu, Dong Hui Wang, Jing Chen, Jing Huang, Hui Li, Yun-Qing Li, Sheng‐Xi Wu et al. · 2018 · Free Radical Biology and Medicine
52. Early Life Stress, Neuroinflammation, and Psychiatric Illness of Adulthood
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53. Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo
    Paul Ikgan Sia, John P. M. Wood, Glyn Chidlow, Robert James Casson · 2019 · Investigative Ophthalmology & Visual Science
54. Friedreich Ataxia: current state-of-the-art, and future prospects for mitochondrial-focused therapies
    Federico Vicente Pallardó, Giovanni Pagano, Laura R. Rodríguez, Pilar González‐Cabo, Alex Lyakhovich, Marco Trifuoggi · 2020 · Translational research
55. Valproate and Acetyl‐ l ‐carnitine Prevent Methamphetamine‐Induced Behavioral Sensitization in Mice
    Roberto Coccurello, Antonio Caprioli, Orlando Ghirardi, Ashraf Virmani · 2007 · Annals of the New York Academy of Sciences
56. α-Synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy
    Clifford W. Shults, Jennifer M. Barrett, Deborah Fontaine · 2006 · Neuroscience Letters
57. Effects of creatine in a rat intestinal model of ischemia/reperfusion injury
    M. Orsenigo, Cristina Porta, Chiara Sironi, Umberto Laforenza, G. Meyer, Marisa Tosco · 2011 · European Journal of Nutrition
58. Role of Acetylcholinesterase Inhibitors and Alzheimer Disease
    Zafar Saied Saify, Nighat Sultana · 2014 · Elsevier eBooks
59. Coenzyme Q1 depletes NAD(P)H and impairs recycling of ascorbate in astrocytes
    Magdalena Dragan, S. Jeffrey Dixon, Ewa M. Jaworski, Tom S. Chan, Peter James O'Brien, John Xavier Wilson · 2006 · Brain Research
60. A prospective, proof-of-concept investigation of KPAX002 in chronic fatigue syndrome.
    Jon D. Kaiser · 2015 · PubMed Central
61. Apparent Opportunities and Hidden Pitfalls: The Conflicting Results of Restoring NRF2-Regulated Redox Metabolism in Friedreich’s Ataxia Pre-Clinical Models and Clinical Trials
    Jessica Tiberi, Marco Segatto, Maria Teresa Fiorenza, Piergiorgio La Rosa · 2023 · Biomedicines
62. The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway
    Jian Xue, Jinbao Zhang, Jinru Zhang, Junyi Liu, Fen Wang, Chun‐Feng Liu, Chun‐Feng Liu · 2023 · Mitochondrion
63. L-carnitine alleviates sciatic nerve crush injury in rats: functional and electron microscopy assessments
    Ümmü Zeynep Avşar, Ümit Avşar, Ali Aydın, Muhammed Yayla, Berna Öztürk, Harun Ün, Murat Sarıtemur, Tolga Mercantepe · 2014 · Neural Regeneration Research
64. Neuroprotective potential of Myrciaria plinioides D. Legrand extract in an in vitro human neuroblastoma model
    Diorge Jônatas Marmitt, Celso Alves, Joana Silva, Susete Pintéus, Taiane Schneider, Roberto Christ Vianna Santos, Elisete Maria de Freitas, Rui Pedrosa, Stefan Laufer, Márcia Inês Goettert · 2019 · Inflammopharmacology
65. Paradigm shift: the end of "normal science" in medicine understanding function in nutrition, health, and disease.
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66. Update on critical evidence for use of carnitine analogs in clinical practice in CNS disorders
    Giovanna Traina · 2011 · Nutrition and Dietary Supplements
67. Improving general intelligence with a nutrient-based pharmacological intervention
    Con K. K. Stough, David Camfield, Christina Kure, Joanne Catherine Tarasuik, Luke A. Downey, Jenny Lloyd, Andrea Zangara, Andrew B Scholey, Josh Reynolds · 2011 · Intelligence
68. Stimulation of electron transport as potential novel therapy in Parkinson's disease with mitochondrial dysfunction
    Melissa Harju Vos, Patrik Verstreken, Christine Klein · 2015 · Biochemical Society Transactions
69. Parkinson's Disease and Mitotherapy-Based Approaches towards α-Synucleinopathies
    Vidhi Bhatt, Halak Shukla, Anand Krishna Tiwari · 2024 · Journal of Integrative Neuroscience
70. Can we prevent parkinson's disease?
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71. The mitochondrial uncoupling effects of nitazoxanide enhances cellular autophagy and promotes the clearance of α-synuclein: Potential role of AMPK-JNK pathway
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72. Current and future therapeutic approaches in progressive supranuclear palsy
    Irene van Balken, Irene Litvan · 2008 · Handbook of clinical neurology
73. Assessment of pharmacokinetic interaction between piracetam and l‐carnitine in healthy subjects
    Gustavo Duarte Mendes, Gabriela Traldi Zaffalon, Antonio Sérgio Silveira, Juliana Cama Ramacciato, Rogério Heládio Lopes Motta, Thiago Gagliano‐Jucá, Aníbal Gil Lopes, José Cássio de Almeida Magalhães, Gilberto De Nucci · 2015 · Biomedical Chromatography
74. Investigation of L-Carnitine Concentrations in Treated Patients with Maple Syrup Urine Disease
    Burcu Kumru, Burcu Öztürk Hişmi · 2019 · Journal of Pediatric Genetics
75. Treatment for Gulf War Illness (GWI) with KPAX002 (methylphenidate hydrochloride + GWI nutrient formula) in subjects meeting the Kansas case definition: A prospective, open-label trial
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76. Effects of Pergolide Mesilate on Metallothionein mRNAs Expression in a Mouse Model for Parkinson Disease
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77. Mitochondria and Parkinson's Disease
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78. Effects of Coenzyme Q10 Administration in Amyotrophic Lateral Sclerosis (ALS). Report of a Case and Review
    Terukazu Kawasaki · 2012 · The Open Nutraceuticals Journal
79. Glutamate and Neurodegeneration
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80. Novel Gene Therapeutic Strategies for Neurodegenerative Diseases
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81. Effects of Creatine Treatment on Jejunal Phenotypes in a Rat Model of Acidosis
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82. Parkinson Disease and the Nurse Practitioner: Diagnostic and Management Challenges
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83. Dietary intake of coenzyme Q10 reduces oxidative stress in patients with acute ischemic stroke: a double-blind, randomized placebo-controlled study
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84. Synergy in Nutrients
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85. Melatonin Deficits Result in Pathologic Metabolic Reprogramming in Differentiated Neurons
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86. Effects of Acetyl-L-Carnitine on Cardiac Arrhythmias and Infarct Size in Ischemic-Reperfused Isolated Rat Heart
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87. Functional foods and cognition
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88. Targeting cellular batteries for the therapy of neurological diseases
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89. Restoring energy in a power crisis: mitochondrial targets for drug development
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90. Neuroprotective agents in Parkinson's disease: clinical evidence and caveats
    Thomas D. Hälbig, Winona Tse, C. Warren Olanow · 2004 · Neurologic Clinics
91. Medical Treatment of Parkinson Disease
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92. Alternative and Non-traditional Treatments of Glaucoma
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93. Redox Imbalance
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94. Neurodegenerative Disorders: The Role of Genetic Factors in Their Origin and the Efficiency of Treatment
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95. Behavior of acetyl-l-carnitine injections (Nicetile® fiale) with different drugs used for combined therapy
    Maria Stefania Sinicropi, Francesco Leone, Nicola Rovito, Giuseppe Genchi · 2010 · Advances in Therapy
96. Mitochondrial Nutrients
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97. Functional proteomics of adenosine triphosphatase system in the rat striatum during aging.
    Roberto Federico Villa, Federica Ferrari, Antonella Gorini · 2012 · Europe PMC (PubMed Central)
98. Neuroprotective treatment for Parkinson’s disease
    Michael J. Aminoff · 2003 · Expert Review of Neurotherapeutics
99. 3-Acetyl-11-Keto-β-Boswellic acid (AKBA) Attenuated 6-Hydroxydopamine (6-OHDA)-Induced Toxicity in SH-SY5Y Cells via Modulation of Akt/mTOR Pathway
    Akram Mohammadi, Azar Hosseini, Maryam Ghobeh, Hamid Reza Sadeghnia · 2025 · Molecular Neurobiology
100. L-carnitine in Hyperammonemia and Hepatic Encephalopathy
     Jane Missler, Claudia Zwingm · 2012 · InTech eBooks