Beal, M. Flint

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

Klivenyi, P., Andreassen, O. A., Ferrante, R. J., Dedeoglu, A., Mueller, G., Lancelot, E., Bogdanov, M., Andersen, J. K., Jiang, D., & Beal, M. F. (2000) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsRedox biology and oxidative stress

Cited by 1,111

Oxidative damage to mitochondrial DNA is increased in Alzheimer’s disease

Mecocci, P., MacGarvey, U., & Beal, M. F. (1994) · Annals of Neurology

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,037

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Cunnane, S. C., Trushina, E., Morland, C., Prigione, A., Casadesus, G., Andrews, Z. B., Beal, M. F., Bergersen, L. H., Brinton, R. D., de la Monte, S., et al. (2020) · Nature Reviews Drug Discovery

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,003

Mitochondrial Dysfunction in Neurodegenerative Diseases

Johri, A., & Beal, M. F. (2012) · The Journal of Pharmacology and Experimental Therapeutics

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 806

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

Yang, Y., Gehrke, S., Imai, Y., Huang, Z., Ouyang, Y., Wang, J.-W., Yang, L., Beal, M. F., Vogel, H., & Lu, B. (2006) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 798

Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo

Kaur, D., Yantiri, F., Rajagopalan, S., Kumar, J., Mo, J. Q., Boonplueang, R., Viswanath, V., Jacobs, R., Yang, L., Beal, M. F., et al. (2003) · Neuron

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 620

Coenzyme Q 10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

Matthews, R. T., Yang, L., Browne, S., Baik, M., & Beal, M. F. (1998) · Proceedings of the National Academy of Sciences

Coenzyme Q10 studies and effectsMitochondrial Function and Pathology

Cited by 557

Neuroprotective Effects of Creatine in a Transgenic Mouse Model of Huntington's Disease

Ferrante, R. J., Andreassen, O. A., Jenkins, B. G., Dedeoglu, A., Kuemmerle, S., Kubilus, J. K., Kaddurah-Daouk, R., Hersch, S. M., & Beal, M. F. (2000) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesParkinson's Disease Mechanisms and Treatments

Cited by 522

Oxidative stress in Huntington’s disease

Browne, S. E., Ferrante, R. J., & Beal, M. F. (1999) · Brain Pathology

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 508

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

Yin, F., Banerjee, R., Thomas, B., Zhou, P., Qian, L., Jia, T., Ma, X., Ma, Y., Iadecola, C., Beal, M. F., et al. (2010) · Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

Cited by 480

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice

Schulz, J. B., Matthews, R. T., Muqit, M. M. K., Browne, S. E., & Beal, M. F. (1995) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 417

Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2

Ramonet, D., Daher, J. P. L., Lin, B. M., Stafa, K., Kim, J., Banerjee, R., Westerlund, M., Pletnikova, O., Glauser, L., Yang, L., et al. (2011) · PLoS ONE

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 405

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10

Koroshetz, W. J., Jenkins, B. G., Rosen, B. R., & Beal, M. F. (1997) · Annals of Neurology

Genetic Neurodegenerative DiseasesCoenzyme Q10 studies and effects

Cited by 405

Therapeutic Effects of Coenzyme Q10and Remacemide in Transgenic Mouse Models of Huntington's Disease

Ferrante, R. J., Andreassen, O. A., Dedeoglu, A., Ferrante, K. L., Jenkins, B. G., Hersch, S. M., & Beal, M. F. (2002) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesCoenzyme Q10 studies and effects

Cited by 391

Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid

Brouillet, E., Jenkins, B. G., Hyman, B. T., Ferrante, R. J., Kowall, N. W., Srivastava, R., Roy, D. S., Rosen, B. R., & Beal, M. F. (1993) · Journal of Neurochemistry

Genetic Neurodegenerative DiseasesMitochondrial Function and Pathology

Cited by 367

Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects

Shults, C. W., Haas, R. H., Passov, D., & Beal, M. F. (1997) · Annals of Neurology

Coenzyme Q10 studies and effectsParkinson's Disease Mechanisms and Treatments

Cited by 326

Marked changes in mitochondrial DNA deletion levels in Alzheimer brains

Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., McKee, A. C., Beal, M. F., Graham, B. H., & Wallace, D. C. (1994) · Genomics

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 309

Excitotoxicity and nitric oxide in parkinson's disease pathogenesis

Beal, M. F. (1998) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 283

Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice

Beal, M. F., Matthews, R. T., Tieleman, A., & Shults, C. W. (1998) · Brain Research

Coenzyme Q10 studies and effectsParkinson's Disease Mechanisms and Treatments

Cited by 256

Reduced Numbers of Somatostatin Receptors in the Cerebral Cortex in Alzheimer's Disease

Beal, M. F., Mazurek, M. F., Tran, V. T., Chattha, G., Bird, E. D., & Martin, J. B. (1985) · Science

Alzheimer's disease research and treatmentsNeuropeptides and Animal Physiology

Cited by 251

The Energetics of Huntington's Disease

Browne, S. E., & Beal, M. F. (2004) · Neurochemical Research

Genetic Neurodegenerative DiseasesNeurological diseases and metabolism

Cited by 240

Bioenergetic approaches for neuroprotection in Parkinson's disease

Beal, M. F. (2003) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsCoenzyme Q10 studies and effects

Cited by 236

Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate

Beal, M. F., Henshaw, D. R., Jenkins, B. G., Rosen, B. R., & Schulz, J. B. (1994) · Annals of Neurology

Coenzyme Q10 studies and effectsMitochondrial Function and Pathology

Cited by 189

The role of mitochondria in inherited neurodegenerative diseases

Kwong, J. Q., Beal, M. F., & Manfredi, G. (2006) · Journal of Neurochemistry

Mitochondrial Function and PathologyHereditary Neurological Disorders

Cited by 180