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A life course approach to cognitive reserve: A model for cognitive aging and development?

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Richards, Marcus, Deary, Ian J.·2005·Annals of Neurology

DOI 10.1002/ana.20637

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Abstract

The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.

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Authors: Richards, M., & Deary, I. J.
Affiliations: The Royal Free Hospital (GB)
Corresponding author: Richards, Marcus
ORCID: Richards, Marcus
Deary, Ian J.
Venue: Annals of Neurology
Publisher: Wiley
Published: 2005-09-21
Volume: 58
Issue: 4
Pages: 617-622
ISSN: 0364-5134 (ISSN-L)
1531-8249
DOI: 10.1002/ana.20637
OpenAlex: W2157174978
Cited by: 331
References: 68
Citations by year: 2026: 3 · 2025: 15 · 2024: 13 · 2023: 23 · 2022: 23 · 2021: 18 · 2020: 20 · 2019: 21 · 2018: 14 · 2017: 16 · 2016: 17 · 2015: 22 · 2014: 16 · 2013: 15 · 2012: 16
FWCI: 7.02
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Annals of Neurology (publishedVersion)
PubMed (publishedVersion)
Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
UCL Discovery (University College London) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Social Sciences › Psychology › Developmental and Educational Psychology › Aging and Gerontology Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
Keywords: cognitive reserve, life course, cognitive aging, cognitive development, neuropathology, brain structure, brain function
MeSH terms: Activities of Daily Living, Aging, Cognition, Humans, Human Development, Models, Biological, Neuropsychological Tests

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A life course approach to cognitive reserve: A model for cognitive aging and development?

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