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A life course approach to cognitive reserve: A model for cognitive aging and development?
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The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.
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“Cognitive ability can be improved across the lifespan based on lifestyle and engagement [44].”
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Metadata
- Authors
- Richards, M., & Deary, I. J.
- Affiliations
- The Royal Free Hospital (GB)
- Corresponding author
- Richards, Marcus
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2005-09-21
- Volume
- 58
- Issue
- 4
- Pages
- 617-622
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2157174978
- Cited by
- 331
- References
- 68
- Citations by year
- 2026: 3 · 2025: 15 · 2024: 13 · 2023: 23 · 2022: 23 · 2021: 18 · 2020: 20 · 2019: 21 · 2018: 14 · 2017: 16 · 2016: 17 · 2015: 22 · 2014: 16 · 2013: 15 · 2012: 16
- FWCI
- 7.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Aging and Gerontology Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Keywords
- cognitive reserve, life course, cognitive aging, cognitive development, neuropathology, brain structure, brain function
- MeSH terms
- Activities of Daily Living, Aging, Cognition, Humans, Human Development, Models, Biological, Neuropsychological Tests
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