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A life course approach to cognitive reserve: A model for cognitive aging and development?
Open accessAbstract
The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.
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“Cognitive ability can be improved across the lifespan based on lifestyle and engagement [44].”
From Social isolation, cognitive reserve, and cognition in healthy older people (2018) · cites this paper as [44]
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Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
Hu, R. J. (2003) · Elsevier eBooks · doi:10.1016/b0-12-226870-9/01070-4 · Cited by 9,168
What is cognitive reserve? Theory and research application of the reserve concept
STERN, Y. (2002) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617702813248 · Cited by 3,951
Compensatory Enlargement of Human Atherosclerotic Coronary Arteries
Glagov, S., Weisenberg, E. S., Zarins, C. K., Stankunavicius, R., & Kolettis, G. (1987) · New England Journal of Medicine · doi:10.1056/nejm198705283162204 · Cited by 3,614
Navigation-related structural change in the hippocampi of taxi drivers
Maguire, E. A., Gadian, D. G., Johnsrude, I. S., Good, C. D., Ashburner, J., Frackowiak, R. S. J., & Frith, C. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.070039597 · Cited by 3,225
Ageing, fitness and neurocognitive function
Kramer, A. F., Hahn, S., Cohen, N. J., Banich, M. T., McAuley, E., Harrison, C. R., Chason, J., Vakil, E., Bardell, L., Boileau, R. A., et al. (1999) · Nature · doi:10.1038/22682 · Cited by 1,394
(2001) · The Lancet · doi:10.1016/s0140-6736(00)03589-3 · Cited by 1,338
Breast-feeding and cognitive development: a meta-analysis
Anderson, J. W., Johnstone, B. M., & Remley, D. T. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.4.525 · Cited by 1,276
Katzman, R., Terry, R., DeTeresa, R., Brown, T., Davies, P., Fuld, P., Renbing, X., & Peck, A. (1988) · Annals of Neurology · doi:10.1002/ana.410230206 · Cited by 1,225
Education and the prevalence of dementia and Alzheimer's disease
Katzman, R. (1993) · Neurology · doi:10.1212/wnl.43.1_part_1.13 · Cited by 1,186
Subcortical ischaemic vascular dementia
Román, G. C., Erkinjuntti, T., Wallin, A., Pantoni, L., & Chui, H. C. (2002) · The Lancet Neurology · doi:10.1016/s1474-4422(02)00190-4 · Cited by 1,067
Hofman, A., Ott, A., Breteler, M. M., Bots, M. L., Slooter, A. J., van Harskamp, F., van Duijn, C. N., Van Broeckhoven, C., & Grobbee, D. E. (1997) · The Lancet · doi:10.1016/s0140-6736(96)09328-2 · Cited by 1,062
Social Disengagement and Incident Cognitive Decline in Community-Dwelling Elderly Persons
Bassuk, S. S., Glass, T. A., & Berkman, L. F. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-131-3-199908030-00002 · Cited by 991
Satz, P. (1993) · Neuropsychology · doi:10.1037/0894-4105.7.3.273 · Cited by 893
Kempermann, G., Gast, D., & Gage, F. H. (2002) · Annals of Neurology · doi:10.1002/ana.10262 · Cited by 889
Cognitive Reserve and Lifestyle
Scarmeas, N., & Stern, Y. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.625.14576 · Cited by 869
The mechanisms mediating the effects of poverty on children’s intellectual development
Guo, G., & Harris, K. M. (2000) · Demography · doi:10.1353/dem.2000.0005 · Cited by 758
The Preclinical Phase of Alzheimer Disease: A 22-Year Prospective Study of the Framingham Cohort
Elias, M. F., Beiser, A., Wolf, P. A., Au, R., White, R. F., & D'Agostino, R. B. (2000) · Archives of Neurology · doi:10.1001/archneur.57.6.808 · Cited by 716
Snowdon, D. A. (1996) · JAMA · doi:10.1001/jama.1996.03530310034029 · Cited by 696
Education modifies the relation of AD pathology to level of cognitive function in older persons
Bennett, D. A., Wilson, R. S., Schneider, J. A., Evans, D. A., Mendes de Leon, C. F., Arnold, S. E., Barnes, L. L., & Bienias, J. L. (2003) · Neurology · doi:10.1212/01.wnl.0000069923.64550.9f · Cited by 549
Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease
Stern, Y., Alexander, G. E., Prohovnik, I., & Mayeux, R. (1992) · Annals of Neurology · doi:10.1002/ana.410320311 · Cited by 470
The Concept of Cognitive Reserve: A Catalyst for Research
Stern, Y. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.589.14571 · Cited by 410
Intellectual Development in Adulthood
Schaie, K. W. (1990) · Elsevier eBooks · doi:10.1016/b978-0-12-101280-9.50023-1 · Cited by 402
Anstey, K., & Christensen, H. (2000) · Gerontology · doi:10.1159/000022153 · Cited by 377
Lifetime Antecedents of Cognitive Reserve
Richards, M., & Sacker, A. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.614.14581 · Cited by 369
Self-citationAssessment of Lifetime Participation in Cognitively Stimulating Activities
Wilson, R. S., Barnes, L. L., & Bennett, D. A. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.634.14572 · Cited by 337
Jefferis, B. J. M. H., Power, C., & Hertzman, C. (2002) · BMJ · doi:10.1136/bmj.325.7359.305 · Cited by 322
Matte, T., Bresnahan, M. A., Begg, M. D., & Susser, E. (2001) · BMJ · doi:10.1136/bmj.323.7308.310 · Cited by 302
Head Circumference, Education and Risk of Dementia: Findings from the Nun Study
Mortimer, J. A., Snowdon, D. A., & Markesbery, W. R. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.671.14584 · Cited by 297
Cognitive change and the APOE ɛ4 allele
Deary, I. J., Whiteman, M. C., Pattie, A., Starr, J. M., Hayward, C., Wright, A. F., Carothers, A. D., & Whalley, L. J. (2002) · Nature · doi:10.1038/418932a · Cited by 296
What provides cerebral reserve?
Staff, R. T., Murray, A. D., Deary, I. J., & Whalley, L. J. (2004) · Brain · doi:10.1093/brain/awh144 · Cited by 285
Kesler, S. R., Adams, H. F., Blasey, C. M., & Bigler, E. D. (2003) · Applied Neuropsychology · doi:10.1207/s15324826an1003_04 · Cited by 280
Childhood mental ability and dementia
Whalley, L. J., Starr, J. M., Athawes, R. W. B., Hunter, D. C., Pattie, A., & Deary, I. J. (2000) · Neurology · doi:10.1212/wnl.55.10.1455 · Cited by 276
Does active leisure protect cognition? Evidence from a national birth cohort.
Richards, M., Hardy, R., & Wadsworth, M. E. J. (2003) · Social Science & Medicine · doi:10.1016/s0277-9536(02)00075-8 · Cited by 264
Self-citationGenetics and general cognitive ability
Plomin, R. J. (1999) · Nature · doi:10.1038/35011520 · Cited by 260
Assessment of lifetime participation in cognitively stimulating activities
Wilson, R. S., Barnes, L. L., & Bennett, D. A. (2013) · Psychology Press eBooks · doi:10.4324/9780203783047-18 · Cited by 259
SCHMAND, B., SMIT, J. H., GEERLINGS, M. I., & LINDEBOOM, J. (1997) · Psychological Medicine · doi:10.1017/s0033291797005461 · Cited by 258
FAMILY AND SCHOOL INFLUENCES ON COGNITIVE DEVELOPMENT
Rutter, M. L. (1985) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1985.tb00584.x · Cited by 251
Becker, J. T., Mintun, M. A., Aleva, K., Wiseman, M. B., Nichols, T. E., & DeKosky, S. T. (1996) · Neurology · doi:10.1212/wnl.46.3.692 · Cited by 242
Early Life Physical Activity and Cognition at Old Age
Dik, M. G., Deeg, D. J. H., Visser, M., & Jonker, C. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.643.14583 · Cited by 241
Intracranial capacity and brain volumes are associated with cognition in healthy elderly men
MacLullich, A. M. J., Ferguson, K. J., Deary, I. J., Seckl, J. R., Starr, J. M., & Wardlaw, J. M. (2002) · Neurology · doi:10.1212/wnl.59.2.169 · Cited by 229
Birthweight, postnatal growth and cognitive function in a national UK birth cohort
Richards, M. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.2.342 · Cited by 215
Self-citationPhysiologic Programming of the Fetus
Seckl, J. R. (1998) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30091-5 · Cited by 210
Pronunciation of irregular words is preserved in dementia, validating premorbid IQ estimation
McGurn, B., Starr, J. M., Topfer, J. A., Pattie, A., Whiteman, M. C., Lemmon, H. A., Whalley, L. J., & Deary, I. J. (2004) · Neurology · doi:10.1212/01.wnl.0000103169.80910.8b · Cited by 184
Does it All Go Together When it Goes? The Nineteenth Bartlett Memorial Lecture
Rabbitt, P. (1993) · The Quarterly Journal of Experimental Psychology Section A · doi:10.1080/14640749308401055 · Cited by 173
Exploring the Neural Basis of Cognitive Reserve
Stern, Y., Zarahn, E., Hilton, H. J., Flynn, J., DeLaPaz, R. L., & Rakitin, B. C. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.691.14573 · Cited by 169
An autopsy-verified study of the effect of education on degenerative dementia
del Ser, T., Hachinski, V., Merskey, H., & Muñoz, D. G. (1999) · Brain · doi:10.1093/brain/122.12.2309 · Cited by 165
The apolipoprotein E varepsilon2 allele and decline in episodic memory
Wilson, R. S. (2002) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.73.6.672 · Cited by 161
Long term effects of early adversity on cognitive function
Richards, M., & Wadsworth, M. E. J. (2004) · Archives of Disease in Childhood · doi:10.1136/adc.2003.032490 · Cited by 156
Self-citationScarmeas, N., Zarahn, E., Anderson, K. E., Hilton, J., Flynn, J., Heertum, R. L. V., Sackeïm, H. A., & Stern, Y. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00074-0 · Cited by 153
Taylor, M. D., Hart, C. L., Smith, G. D., Starr, J. M., Hole, D. J., Whalley, L. J., Wilson, V., & Deary, I. J. (2003) · Journal of Epidemiology & Community Health · doi:10.1136/jech.57.6.464 · Cited by 151
Short anxiety screening test—a brief instrument for detecting anxiety in the elderly
Sinoff, G., Ore, L., Zlotogorsky, D., & Tamir, A. (1999) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(199912)14:12 · Cited by 137
Birth weight and cognitive function at age 11 years: the Scottish Mental Survey 1932
Shenkin, S. D. (2001) · Archives of Disease in Childhood · doi:10.1136/adc.85.3.189 · Cited by 115
Head circumference and incident Alzheimer’s disease
Graves, A. B., Mortimer, J. A., Bowen, J. D., McCormick, W. C., McCurry, S. M., Schellenberg, G. D., & Larson, E. B. (2001) · Neurology · doi:10.1212/wnl.57.8.1453 · Cited by 103
Childhood mental ability and blood pressure at midlife
Starr, J. M., Taylor, M. D., Hart, C., Smith, G. D., Whalley, L. J., Hole, D. J., Wilson, V., & Deary, I. J. (2004) · Journal of Hypertension · doi:10.1097/00004872-200405000-00009 · Cited by 99
Individual differences in trajectory of intellectual development over 45 years of adulthood.
Arbuckle, T. Y., Maag, U., Pushkar, D., & Chaikelson, J. S. (1998) · Psychology and Aging · doi:10.1037/0882-7974.13.4.663 · Cited by 97
Vascular abnormalities: the insidious pathogenesis of Alzheimer’s disease☆
Shi, J., Perry, G. L., Smith, M. A., & Friedland, R. P. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00119-6 · Cited by 89
Hassan, A. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.72.3.343 · Cited by 88
Deary, I. J., Whiteman, M. C., Pattie, A., Starr, J. M., Hayward, C., Wright, A. F., Visscher, P. M., Tynan, M. C., & Whalley, L. J. (2004) · Psychology and Aging · doi:10.1037/0882-7974.19.2.367 · Cited by 76
Roth, M., Tomlinson, B. E., & Blessed, G. (1967) · PubMed · Cited by 59
Genetic Evidence for Cognitive Reserve: Variations in Memory and Related Cognitive Functions
Lee, J. H. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.594.14582 · Cited by 59
Reynolds, M., Johnston, J. M., Dodge, H. H., DeKosky, S. T., & Ganguli, M. (1999) · Neurology · doi:10.1212/wnl.53.1.228 · Cited by 59
Progressive Decline in Nart Score with Increasing Dementia Severity
Cockburn, J., Keene, J., Hope, T., & Smith, P. (2000) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/1380-3395(200008)22:4;1-0;ft508 · Cited by 55
Barker, Brenner, and Babies—Early environment and renal disease in adulthood
Garrett, P., Bass, P. S., & Sandeman, D. D. (1994) · The Journal of Pathology · doi:10.1002/path.1711730402 · Cited by 29
National Adult Reading Test performance in established dementia
Taylor, R. (2000) · Archives of Gerontology and Geriatrics · doi:10.1016/s0167-4943(99)00042-4 · Cited by 25
Aspects of Psychiatry in the Elderly
Roth, M., Tomlinson, B. E., & Blessed, G. (1967) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591576706000327 · Cited by 20
McKhann, G. M. (2002) · Annals of Neurology · doi:10.1002/ana.10303 · Cited by 9
Research works printed but not linked: 1
- Barker DJP, 1998, Mothers, babies and health in later life
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The Impact of Age on Cognition
Murman, D. (2015) · Seminars in Hearing · doi:10.1055/s-0035-1555115 · Cited by 1,619
Age-associated cognitive decline
Deary, I. J., Corley, J., Gow, A. J., Harris, S. E., Houlihan, L. M., Marioni, R. E., Penke, L., Rafnsson, S. B., & Starr, J. M. (2009) · British Medical Bulletin · doi:10.1093/bmb/ldp033 · Cited by 1,295
Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
Qiu, C., Kivipelto, M., & von Strauss, E. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.2/cqiu · Cited by 1,261
Bilingualism delays age at onset of dementia, independent of education and immigration status
Alladi, S., Bak, T. H., Duggirala, V., Surampudi, B., Shailaja, M., Shukla, A. K., Chaudhuri, J. R., & Kaul, S. (2013) · Neurology · doi:10.1212/01.wnl.0000436620.33155.a4 · Cited by 543
Metadata
- Authors
- Richards, M., & Deary, I. J.
- Affiliations
- The Royal Free Hospital (GB)
- Corresponding author
- Richards, Marcus
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2005-09-21
- Volume
- 58
- Issue
- 4
- Pages
- 617-622
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2157174978
- Cited by
- 331
- References
- 68
- Citations by year
- 2026: 3 · 2025: 15 · 2024: 13 · 2023: 23 · 2022: 23 · 2021: 18 · 2020: 20 · 2019: 21 · 2018: 14 · 2017: 16 · 2016: 17 · 2015: 22 · 2014: 16 · 2013: 15 · 2012: 16
- FWCI
- 7.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Aging and Gerontology Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Keywords
- cognitive reserve, life course, cognitive aging, cognitive development, neuropathology, brain structure, brain function
- MeSH terms
- Activities of Daily Living, Aging, Cognition, Humans, Human Development, Models, Biological, Neuropsychological Tests
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