Cited by 1,000Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury ResearchNeuroinflammation and Neurodegeneration Mechanisms

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Inflammation after trauma: Microglial activation and traumatic brain injury

Ramlackhansingh, Anil F., Brooks, David J., Greenwood, Richard J., Bose, Subrata K., Turkheimer, Federico E., Kinnunen, Kirsi M., Gentleman, Steve, Heckemann, Rolf A., Gunanayagam, Karen, Gelosa, Giorgio, Sharp, David J.·2011·Annals of Neurology

DOI 10.1002/ana.22455

Open this paper in CoChat — free account

Abstract

Objective: Patient outcome after traumatic brain injury (TBI) is highly variable. The underlying pathophysiology of this is poorly understood, but inflammation is potentially an important factor. Microglia orchestrate many aspects of this response. Their activation can be studied in vivo using the positron emission tomography (PET) ligand [11C](R)PK11195 (PK). In this study, we investigate whether an inflammatory response to TBI persists, and whether this response relates to structural brain abnormalities and cognitive function. Methods: Ten patients, studied at least 11 months after moderate to severe TBI, underwent PK PET and structural magnetic resonance imaging (including diffusion tensor imaging). PK binding potentials were calculated in and around the site of focal brain damage, and in selected distant and subcortical brain regions. Standardized neuropsychological tests were administered. Results: PK binding was significantly raised in the thalami, putamen, occipital cortices, and posterior limb of the internal capsules after TBI. There was no increase in PK binding at the original site of focal brain injury. High PK binding in the thalamus was associated with more severe cognitive impairment, although binding was not correlated with either the time since the injury or the extent of structural brain damage. Interpretation: We demonstrate that increased microglial activation can be present up to 17 years after TBI. This suggests that TBI triggers a chronic inflammatory response particularly in subcortical regions. This highlights the importance of considering the response to TBI as evolving over time and suggests interventions may be beneficial for longer intervals after trauma than previously assumed. ANN NEUROL 2011;

Integrity signals

Registry

Crossref · 10.1002/ana.22455

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Microglia: Intrinsic immuneffector cell of the brain
Gehrmann, J., Matsumoto, Y., & Kreutzberg, G. W. (1995) · Brain Research Reviews · doi:10.1016/0165-0173(94)00015-h · Cited by 1,111
A population-based study of seizures after traumatic brain injuries
Annegers, J. F., Hauser, W. A., Coan, S. P., & Rocca, W. A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801013380104 · Cited by 1,090
Systemic infections and inflammation affect chronic neurodegeneration
Perry, V. H., Cunningham, C., & Holmes, C. (2007) · Nature Reviews Immunology · doi:10.1038/nri2015 · Cited by 1,027
Automatic anatomical brain MRI segmentation combining label propagation and decision fusion
Heckemann, R. A., Hajnal, J. V., Aljabar, P., Rueckert, D., & Hammers, A. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.05.061 · Cited by 865
Self-citation
Inflammatory Neurodegeneration Mediated by Nitric Oxide from Activated Glia-Inhibiting Neuronal Respiration, Causing Glutamate Release and Excitotoxicity
Bal-Price, A., & Brown, G. C. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-17-06480.2001 · Cited by 686
White matter damage and cognitive impairment after traumatic brain injury
Kinnunen, K. M., Greenwood, R., Powell, J. H., Leech, R., Hawkins, P. C. T., Bonnelle, V., Patel, M. C., Counsell, S. J., & Sharp, D. J. (2010) · Brain · doi:10.1093/brain/awq347 · Cited by 685
Self-citation
Update of Neuropathology and Neurological Recovery After Traumatic Brain Injury
Povlishock, J. T., & Katz, D. I. (2005) · Journal of Head Trauma Rehabilitation · doi:10.1097/00001199-200501000-00008 · Cited by 676
The Mayo Classification System for Traumatic Brain Injury Severity
Malec, J. F., Brown, A. W., Leibson, C. L., Flaada, J. T., Mandrekar, J. N., Diehl, N. N., & Perkins, P. K. (2007) · Journal of Neurotrauma · doi:10.1089/neu.2006.0245 · Cited by 673
Essential protective roles of reactive astrocytes in traumatic brain injury
Myer, D. J. (2006) · Brain · doi:10.1093/brain/awl165 · Cited by 637
Head injury and the risk of AD in the MIRAGE study
Guo, Z., Cupples, L. A., Kurz, A., Auerbach, S. H., Volicer, L., Chui, H., Green, R. C., Sadovnick, A. D., Duara, R., DeCarli, C., et al. (2000) · Neurology · doi:10.1212/wnl.54.6.1316 · Cited by 506

Flagged first, then by citations

Show all 32 references

Sorted by citations

Items 801–900 of 1,000

On Overcoming Barriers to Application of Neuroinflammation Research
Tobinick, E., Ignatowski, T., & Spengler, R. (2017) · InTech eBooks · doi:10.5772/intechopen.68940 · Cited by 3
Cognitive-Emotional-Vestibular Triad in Mild Traumatic Brain Injury
Banerjee, N., Getz, S. J., & Levin, B. E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812344-7.00013-3 · Cited by 3
Increased Noise in Cortico-Cortical Integration After Mild TBI Measured With the Equivalent Noise Technique
Ruíz, T., Baldwin, A. S., Spiegel, D. P., Hess, R. F., & Farivar, R. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00767 · Cited by 2
Electrophysiological Biomarkers for Mood Disorders
Ramakrishnan, N., Murphy, N., Selvaraj, S., & Cho, R. Y. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.015 · Cited by 2
Neuroinflammation in Alzheimer's Disease
(2020) · Case Medical Research · doi:10.31525/ct1-nct04274998 · Cited by 2
Proteinopathies and Neurotrauma: Update on Degenerative Cascades.
Quintin, S. S., Sorrentino, Z. A., Mehkri, Y., Sriram, S., Weisman, S., Davidson, C. G., Lloyd, G. M., Sung, E., Figg, J., & Lucke-Wold, B. P. (2022) · PubMed · Cited by 2
A Repeated Measures Pilot Comparison of Trajectories of Fluctuating Endogenous Hormones in Young Women with Traumatic Brain Injury, Healthy Controls
Niemeier, J. P., Perrin, P. B., Hurst, B. S., Foureau, D., Huynh, T. T., Evans, S. L., Silverman, J. E., McClannahan, M. E., Brusch, B. D., Newman, M. A., et al. (2019) · Behavioural Neurology · doi:10.1155/2019/7694503 · Cited by 2
Hubungan antara trauma kepala dan fungsi kognitif pada usia dewasa muda
Pramana, R., & Imran, Y. (2019) · Jurnal Biomedika dan Kesehatan · doi:10.18051/jbiomedkes.2019.v2.149-153 · Cited by 4
From seed to flower: blossoming of microglia in development and brain repair
Neckles, V. N., & Feliciano, D. M. (2021) · Cell and Tissue Research · doi:10.1007/s00441-021-03486-9 · Cited by 2
Mismatch Negativity (MMN) and P3a Abnormalities in Traumatic Brain Injury
Kaipio, M.-L. (2016) · Työväentutkimus Vuosikirja · Cited by 2
Region-specific homeostatic identity of astrocytes is essential for defining their reactive phenotypes following pathological insultsPreprint
Makarava, N., Mychko, O., Molesworth, K., Chang, J. C., Henry, R. J., Tsymbalyuk, N., Gerzanich, V., Simard, J. M., Loane, D. J., & Baskakov, I. V. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.01.526708 · Cited by 2
Transcranial, red/near-infrared light-emitting diode therapy for chronic traumatic brain injury and poststroke aphasia: clinical studies
Naeser, M. A., Martin, P. I., Ho, M. D., Krengel, M., Bogdanova, Y., Knight, J., Fedoruk, A., Hamblin, M. R., & Koo, B. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815305-5.00025-7 · Cited by 1
Posttraumatic and Idiopathic Spike–Wave Discharges in Rats: Discrimination by Morphology and Thalamus Involvement
Komoltsev, I., Salyp, O., Volkova, A., Bashkatova, D., Shirobokova, N., Frankevich, S., Shalneva, D., Kostyunina, O., Chizhova, O., Kostrukov, P., et al. (2023) · Neurology International · doi:10.3390/neurolint15020038 · Cited by 1
Statins could improve short-term prognosis in patients with traumatic brain injury: a propensity-matched cohort study
Li, P., Liu, Q., Zhang, Z., & Nie, H. (2025) · Inflammopharmacology · doi:10.1007/s10787-025-01803-0 · Cited by 1
Realization of differential release of minocycline hydrochloride from electrosprayed polymeric or biomacromolecular microparticles for the repair of traumatic brain injury
Guo, Q., Wang, Y., Fu, M., Zhou, Z., Zhang, X., Chen, S., Xu, C., Wang, Y., & Wu, T. S. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102309 · Cited by 1
Triggering Receptor Expressed on Myeloid Cell 2-Mediated Microglial Phagocytosis in the Subacute Phase of Traumatic Brain Injury Exacerbates Impaired Memory
Xia, J., Sun, C., Su, T., Xia, S.-Y., Zhao, S.-Z., & Zhang, Y.-M. (2025) · Journal of Neurotrauma · doi:10.1177/08977151251388041 · Cited by 2
The Gut Microbiome as a Modulator of Traumatic Brain Injury Pathology and Symptoms
Haar, C. V., Celorrio, M., Martens, K. M., Friess, S. H., Villapol, S., Urban, R. J., Pyles, R. B., Mychasiuk, R., Simon, D. W., & Dave, A. M. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1337-25.2025 · Cited by 1
Sleep spindle density and morphology are resilient to post-traumatic gray matter volume loss
Kalantari, N., Daneault, V., Blais, H., André, C., Sanchez, E., Lina, J., Arbour, C., Gilbert, D., Carrier, J., & Gosselin, N. (2025) · NeuroImage Clinical · doi:10.1016/j.nicl.2025.103915 · Cited by 1
Nanomedicine in neurotrauma: A comprehensive review of gold nanoparticles for traumatic brain injury treatment
Monfared, E. H., Fathi-karkan, S., & Keshavarzi, Z. (2026) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.115922 · Cited by 2
Relevance of cerebral microbleeds with leaky blood brain barrier in traumatic brain injury and protective role of interferon-gamma: A cohort study
To, X. V., Urriola, J., Vegh, V., Donnelly, P., Maclachlan, L., Mahady, K., Apellaniz, E. M., Lim, R., Gonzalez, G. C., Wenger, R., et al. (2025) · Cerebral Circulation - Cognition and Behavior · doi:10.1016/j.cccb.2025.100523 · Cited by 1
Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome
Taylor, M. A., Boland, R., Houle, S., Tapp, Z. M., Davis, A. C., Cotter, C., Sheridan, J. F., Godbout, J., & Kokiko‐Cochran, O. N. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1689773 · Cited by 1
Advancing EEG-based assessment of consciousness and cognition in prolonged disorders of consciousness
du Bois, N., Korik, A., Hodge, S., Hudson, L., Elahi, A. S., Bigirimana, A., Dayan, N., Sanchez-Bornot, J. M., McCann, A., Yelden, K., et al. (2026) · Communications Medicine · doi:10.1038/s43856-026-01574-x · Cited by 2
A consensus roadmap for post‐traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials
Zanier, E. R., Lisi, I., O'Loughlin, E. K., Moro, F., Amorim, E., Brody, D. L., Correa, D. J., Duncan, D., Klein, P., Kobeissy, F. H., et al. (2026) · Epilepsia · doi:10.1002/epi.70238 · Cited by 1
Primary Blast-Induced Traumatic Brain Injury as a Risk Factor for (Cerebro)vascular Disorder: Clinical Manifestations, Blast Physics, Biomechanics, Pathobiology, and Critical Gaps
Agoston, D. V., & Meabon, J. S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27114669 · Cited by 3
Elevated translocator protein in skull bone marrow is linked to human chronic pain
Mohammadian, M., Efthimiou, N., Gabriel, K. A., Brusaferri, L., Cooper-Hohn, J., Kim, M., Murphy, J. P., Alshelh, Z., Grmek, G., Schnieders, J. H., et al. (2026) · Science Translational Medicine · doi:10.1126/scitranslmed.aed8729 · Cited by 4
Self-citation
Lack of effect of repetitive mild traumatic brain injury early in life on the neuropathological and behavioral hallmarks of Alzheimer's disease in 3xTg-AD mice
Barker, C., Koza, L. A., Almuhanna, L., Trujillo, K. R., & Linseman, D. A. (2026) · Journal of Alzheimer s Disease · doi:10.1177/13872877261476274 · Cited by 1
MICROGLIA ACTIVATION IN A RODENT MODEL OF AN ALCOHOL USE DISORDER: THE IMPORTANCE OF PHENOTYPE, INITIATION, AND DURATION OF ACTIVATION
Marshall, S. A. (2013) · UKnowledge (University of Kentucky) · Cited by 1
Monitoring of Acute Traumatic Brain Injury In Adults To Prevent Secondary Brain Damage
Bothe, M. K., & Stover, J. F. (2014) · Future Neurology · doi:10.2217/fnl.13.78 · Cited by 1
Acute, Subacute and Chronic Biomarkers for CNS Injury
Zhiqun Zhang, A. M. A. K. K. W. W. (2014) · CRC Press eBooks · doi:10.1201/b17644-11 · Cited by 1
Analyzing Mortality Risk and Medical Burden among Patients with Traumatic Brain Injury and Subsequent Dementia
Harnod, D., Harnod, T., Lin, C., & Kao, C. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8050686 · Cited by 1
Sports-Related Subconcussive Head Trauma
Johnson, B. (2021) · Springer eBooks · doi:10.1007/978-3-030-75564-5_12 · Cited by 1
Inflammation and posttraumatic epilepsy
Jonak, C. R., Peterson, A. R., & Binder, D. K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90099-7.00012-5 · Cited by 1
Cerebral Gray Matter May Not Explain Sleep Slow-Wave Characteristics after Severe Brain Injury
Kalantari, N., Daneault, V., Blais, H., André, C., Sanchez, E., Lina, J., Arbour, C., Gilbert, D., Carrier, J., & Gosselin, N. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1306-23.2024 · Cited by 2
FEATURES OF IMMUNOLOGICAL REACTIVITY OF PATIENTS WITH COMBAT TRAUMATIC BRAIN INJURY DEPENDING ON ITS TYPE AND CHRONICIT
Geiko, V. V., Лемонджава, З. М., & Посохов, М. Ф. (2025) · Ukrains kyi Visnyk Psykhonevrolohii · doi:10.36927/2079-0325-v33-is1-2025-2 · Cited by 1
PET Imaging of Microglia Activation in Neuropsychiatric Disorders with Potential Infectious Origin
Klein, H. C., de Witte, L. D., Bransfield, R. C., & Deyn, P. P. D. (2014) · Springer eBooks · doi:10.1007/978-3-642-54307-4_34 · Cited by 1
Viability Changes in Leucocytes in a Critical Trauma Patient: Monocyte, Lymphocyte, Granulocyte Response to the Acute Phase: Case Report
Benedek, O., Dobreanu, M., Azamfirei, L., Veres, M., & Copotoiu, S. (2016) · Acta Marisiensis. Seria Medica · doi:10.1515/amma-2015-0099 · Cited by 1
Can Sustained Glia-Mediated Brain Inflammation After Repeated Concussive Brain Injury Be Detected In Vivo?
Witcher, K. G., & Godbout, J. P. (2016) · JAMA Neurology · doi:10.1001/jamaneurol.2016.4539 · Cited by 1
Neurobiological and connectivity changes after sports-related concussion
Krongold, M., & Chow, N. (2017) · University of Western Ontario Medical Journal · doi:10.5206/uwomj.v86i1.2144 · Cited by 1
[Effects of cysteinyl leukotriene receptors on phagocytosis of mouse microglial cells].
Wang, X., Yunbi, L., Zhang, W., Wei, E., & Fang, S. (2018) · PubMed Central · doi:10.3785/j.issn.1008-9292.2018.02.02 · Cited by 1
Inflammation, Neurovascular Clearance and Associated Pathologies: A Translational Review Focusing on Traumatic Brain Injury
Lindblad, C., & Thelin, E. P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11528-4 · Cited by 1
PET Imaging of Microglia Activation and Infection in Neuropsychiatric Disorders with Potential Infectious Origin
Klein, H. C., de Witte, L. D., Bransfield, R. C., & Deyn, P. P. D. (2020) · Springer eBooks · doi:10.1007/978-3-030-53168-3_32 · Cited by 1
Brain Imaging and the Mechanisms of Antidepressant Action
Godlewska, B. R., Selvaraj, S., & Cowen, P. J. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.020 · Cited by 1
Effects of Lithium on Brain Structure in Bipolar Disorder
Kaur, J., Kafantaris, V., & Szeszko, P. R. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.018 · Cited by 1
Functional Connectome in Bipolar Disorder
Cha, J., & Anand, A. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.008 · Cited by 1
Traumatic Brain Injury: Nuclear Medicine Neuroimaging
Sánchez-Catasús, C. A., Stormezand, G. N., García, D. V., Morales, E. L. R., Sánchez, R. G., & Dierckx, R. A. J. O. (2020) · Springer eBooks · doi:10.1007/978-3-030-53168-3_43 · Cited by 1
Post‐ischemic protection of hepatocyte growth factor requires the type II transmembrane serine protease matriptase—A reciprocal regulation of the two for neuroprotection in stroke brain
Lee, S., Lee, M. H., Wu, K., Chiang, C., Chang, Y.-X., Fang, J., Tung, H., Kuo, L., & Wang, Y. (2022) · The FASEB Journal · doi:10.1096/fj.202200414r · Cited by 1
How molecular imaging studies can disentangle disease mechanisms in age-related neurodegenerative disorders
de Natale, E. R., Wilson, H., Udeh‐Momoh, C. T., Ford, J. K., Politis, M., & Middleton, L. T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823761-8.00022-7 · Cited by 1
Investigating neuroinflammation in lateral fluid percussion injury
Tapp, Z. M., & Kokiko‐Cochran, O. N. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89833-1.00023-9 · Cited by 1
Cell Proliferation in the Brains of Adult Rats Exposed to Traumatic Brain Injury
Acosta, S. A., Tajiri, N., Bickford, P. C., & Borlongan, C. V. (2013) · Wiley eBooks · doi:10.1002/9781118444177.ch2 · Cited by 1
Traumatic Brain Injury and Neurodegenerative Disease
McGuire, D. (2018) · Wiley eBooks · doi:10.1002/9781118772034.ch26 · Cited by 2
Tau and beta-amyloid deposition, structural integrity, and cognitive function following traumatic brain injury in Australian war veterans
Cummins, T. L. (2018) · Minerva Access (University of Melbourne) · Cited by 1
Diffuse TBI-induced expression of anxiety-like behavior coincides with altered glutamatergic function, TrkB protein levels and region-dependent pathophysiology in amygdala circuitryPreprint
Beitchman, J. A., Griffiths, D. R., Hur, Y., Ogle, S. B., Hair, C. E., Morrison, H. W., Lifshitz, J., Adelson, P. D., & Thomas, T. C. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/640078 · Cited by 1
Toxicity Screening of Novel Myeloperoxidase Inhibitors Using Zebrafish Model
Fadan, M. (2018) · Cited by 1
Editorial: Traumatic Brain Injury: From Bench to Bedside
de Miranda, A. S., de Souza, L. C., & Teixeira, A. L. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.01214 · Cited by 1
Environmental and genetic risk factors for Parkinson’s disease
Никитина, М. А., Alifirova, V. M., Bragina, E. Y., Бабушкина, Н. П., Gomboeva, D. E., & Nazarenko, M. S. (2023) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2022-4-105-113 · Cited by 1
Assessing the Impact of Multiple Common Factors on the Development of Parkinson’s Disease: An Updated Narrative ReviewPreprint
Jbaily, H. (2023) · Preprints.org · doi:10.20944/preprints202312.2099.v1 · Cited by 1
WITHDRAWN: Evidence Suggesting Prolonged Neuroinflammation in a Subset of Children after Moderate/Severe TBI: A UCLA RAPBI StudyPreprint
McCabe, C., Dennis, E. L., Lindsey, H. M., Babikian, T., Bickart, K. C., Giza, C. C., & Asarnow, R. F. (2025) · medRxiv · doi:10.1101/2025.01.20.25320782 · Cited by 1
Spinal Cord and Brain Trauma
David, S., & Popovich, P. G. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1429-6_19
In vivo assessment of amyloid deposition, neuroinflammation, and metabolic changes in neurodegenerations of different origin
Ramlackhansingh, A. F. (2013) · doi:10.25560/23658
Self-citation
In Vivo Imaging of Neuroinflammation in Acute Brain Injury
Thiel, A. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8915-3_13
The Role of Microglial Subsets in Regulating Traumatic Brain Injury
Seaman, W. E. (2012) · Defense Technical Information Center (DTIC) · doi:10.21236/ada581397
Cellular and Molecular Responses to Traumatic Brain Injury
Lööv, C. (2014) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Neuroprotective strategies for traumatic brain injury
Yin, T. C. (2015) · doi:10.17077/etd.c8l4gi2h
Toll-Like Receptors and Neuroinflammation
Lee, S. J. (2013) · Advances in neurobiology · doi:10.1007/978-1-4614-8313-7_9
The Effect of Head Injury on Neurologic and Cognitive Health Throughout the Life Course
Taylor, K. M. (2015) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
Neuroinflammatory Alterations via CD-36 in Traumatic Brain Injury
Hernandez‐Ontiveros, D. G. (2015) · Digital Commons - University of South Florida (University of South Florida)
Migration von Monozyten nach Injektion in das lädierte Zentrale Nervensystem
Kaminski, M. (2012) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-12485
What′s new in emergencies, trauma, and shock? Heparin in severe traumatic brain injury: Beyond venous thromboembolism prevention?
Masotti, L., Napoli, M. D., Godoy, D. A., & Lorenzini, G. (2014) · Journal of Emergencies Trauma and Shock · doi:10.4103/0974-2700.136842
Impact of genetic variability on early immune reactions following nerve injury
Lindblom, R. P. F. (2013) · Figshare
Cortical Excitability after Mild Traumatic Brain Injury in Children
Seeger, T. (2015) · doi:10.5072/prism/25470
The influence of pediatric concussion on cognitive control and neuroelectric function
Moore, R. D. (2014) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
HISTOLOGICAL AND BEHAVIORAL CONSEQUENCES OF REPEATED MILD TRAUMATIC BRAIN INJURY IN MICE
Hall, B. (2016) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2016.165
Apprendere l'italiano oggi
Micheli, P. (2008) · Revista de Italianística · doi:10.11606/issn.2238-8281.v0i17p13-21
Mediators of neuroinflammation
Tikamdas, R., Zhang, P., & Liu, B. (2016) · Wiley eBooks · doi:10.1002/9781118832431.ch4
Monitoring and Assessment Technologies Cognitive changes and dementia risk after traumatic brain injury: Implications for aging military personnel *
Vincent, A. S., Roebuck‐Spencer, T., & Cernich, A. N. (2014)
Low-Level Laser (Light) Therapy for Rehabilitation in Traumatic Brain Injury and Stroke, including Chronic Aphasia
Naeser, M. A., Martin, P. I., Ho, M. D., Krengel, M., Bogdanova, Y., Knight, J., Yee, M. K., ZAFONTE, R. D., Koo, B., Roubil, J. G., et al. (2016)
One Step at a Time, Stem Cell Therapy for Traumatic Brain Injury Needs Two More Breakthroughs
Lois, T. (2016)
Neural Substrates of Parkinson's Disease
Koshimori, Y. (2016) · TSpace (University of Toronto)
Novel Protein Delivery Platforms to Modulate SDF-1α/CXCR4 Signaling in the Adult Cortex
Dutta, D. (2016)
Impact of anti-viral immunity on neural stem/progenitor cell activity and implications for CNS development
Kulkarni, A. (2017)
The Effects of Mild Concussions and Pomegranates on Behavior
Bajwa, N. M. (2016) · The Scholars Repository - LLU (Loma Linda University)
Molecular basis for amyloid precursor protein mediated neuroprotection in traumatic brain injury
Inampudi, C. (2019) · Minerva Access (University of Melbourne)
Estudo da correlação entre a razão de transferência de magnetização e a volumetria em pacientes com lesão axonal traumática
Macruz, F. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2019.tde-07052019-112605
Chronic traumatic encephalopathy: the nature, mechanisms and stages of development
Eg, P., & Лисяный, Н. И. (2019) · Ukrainian Neurosurgical Journal · doi:10.25305/unj.168890
Neurodegeneration and Dementia following Traumatic Brain Injury
Marklund, N. (2020) · Springer eBooks · doi:10.1007/978-3-030-39383-0_86
Current State of the Art in Neurotrauma Research
Maas, A. I. R., Menon, D. K., & Marklund, N. (2020) · Springer eBooks · doi:10.1007/978-3-030-39383-0_88
Imaging Genetic and Epigenetic Markers in Mood Disorders
Poletti, S., Mazza, E. A., Vai, B., & Benedetti, F. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.012
Brain Imaging of Reward Dysfunction in Unipolar and Bipolar Disorders
Kumar, P., Jiang, Y., & Whitton, A. E. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.006
Resting-State Functional Connectivity in Unipolar Depression
Chen, Z., & Gong, Q. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.007
Brain Imaging Methods in Mood Disorders
Selvaraj, S., Brambilla, P., & Soares, J. C. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.002
Magnetic Resonance Spectroscopy Investigations of Bioenergy and Mitochondrial Function in Mood Disorders
Kious, B. M., & Renshaw, P. F. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.009
Neuroimaging Brain Inflammation in Mood Disorders
Meyer, J. H. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.011
Functional Near-Infrared Spectroscopy Studies in Mood Disorders
Matsuo, K., & Matsubara, T. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.014
The Role of High-Fat Diets in Exacerbating Cognitive Deficits After Traumatic Brain Injury
Frankot, M. A. (2020) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.7759
Neuroanatomical Findings in Unipolar Depression and the Role of the Hippocampus
Arnone, D. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.003
Neuroimaging Biomarkers in Pediatric Mood Disorders
West, M. P., Tang, W. J., & Singh, M. K. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.005
fMRI Neurofeedback as Treatment for Depression
Skottnik, L., & Linden, D. E. J. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.013
Neuroanatomical Findings in Bipolar Disorder
Tronchin, G., & McDonald, C. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.004
Imaging Glutamatergic and GABAergic Abnormalities in Mood Disorders
Scotti-Muzzi, E., Otaduy, M. C. G., Soeiro‐de‐Souza, M. G., & Machado‐Vieira, R. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.010
Molecular Imaging of Dopamine and Antipsychotics in Bipolar Disorder
Jauhar, S. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.019

Authors: Ramlackhansingh, A. F., Brooks, D. J., Greenwood, R. J., Bose, S. K., Turkheimer, F. E., Kinnunen, K. M., Gentleman, S., Heckemann, R. A., Gunanayagam, K., Gelosa, G., & Sharp, D. J.
Affiliations: Hammersmith Hospital (GB)
UCL Queen Square Institute of Neurology (GB)
Goldsmiths University of London (GB)
Corresponding author: Sharp, David J.
ORCID: Brooks, David J.
Turkheimer, Federico E.
Kinnunen, Kirsi M.
Gentleman, Steve
Heckemann, Rolf A.
Sharp, David J.
Venue: Annals of Neurology
Publisher: Wiley
Published: 2011-06-27
Volume: 70
Issue: 3
Pages: 374-383
ISSN: 0364-5134 (ISSN-L)
1531-8249
DOI: 10.1002/ana.22455
OpenAlex: W2096019298
Cited by: 999
References: 32
Citations by year: 2026: 40 · 2025: 57 · 2024: 60 · 2023: 62 · 2022: 71 · 2021: 104 · 2020: 92 · 2019: 86 · 2018: 66 · 2017: 71 · 2016: 71 · 2015: 75 · 2014: 58 · 2013: 49 · 2012: 31
FWCI: 28.64
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Annals of Neurology (publishedVersion)
PubMed (publishedVersion)
BOA (University of Milano-Bicocca) (submittedVersion)
UCL Discovery (University College London) (submittedVersion)
Research Portal (King's College London) (submittedVersion)
Funders: Imperial College Healthcare Charity
Dunhill Medical Trust
Medical Research Council
Topics: Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Keywords: traumatic brain injury, microglial activation, neuroinflammation, [11C]PK11195 PET, thalamus, cognitive impairment, subcortical structures, diffusion tensor imaging, structural brain abnormalities
MeSH terms: Adult, Amnesia, Brain Injuries, Cognition Disorders, Educational Status, Female, Humans, Image Processing, Computer-Assisted, Inflammation, Isoquinolines, Macrophage Activation, Magnetic Resonance Imaging, Male, Memory, Middle Aged, Neuropsychological Tests, Thalamus, Wechsler Scales, Glasgow Coma Scale, Cluster Analysis, Microglia, Positron-Emission Tomography, Diffusion Tensor Imaging, Executive Function

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Inflammation after trauma: Microglial activation and traumatic brain injury

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks