Inflammatory Neurodegeneration Mediated by Nitric Oxide from Activated Glia-Inhibiting Neuronal Respiration, Causing Glutamate Release and Excitotoxicity
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Microglial derived nitric oxide inhibits neuronal respiration, resulting in glutamate release and subsequent excitotoxicity.
“On the other hand, microglial derived nitric oxide inhibits neuronal respiration, resulting in glutamate release and subsequent excitotoxicity44,45.”
From TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity (2020) · cites this paper as [45]
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Liberatore, G. T., Jackson-Lewis, V., Vukosavic, S., Mandir, A. S., Vila, M., McAuliffe, W. G., Dawson, V. L., Dawson, T. M., & Przedborski, S. (1999) · Nature Medicine · doi:10.1038/70978 · Cited by 1,046 · cited 1× · see citing works
“…neurons in coculture (Chao, 1996; Hu et al., 1997; Kingham et al., 1999; Tanabe et al., 1999), and this may occur in vivo during brain trauma, inflammation, post-ischemia, and infection, and in neurodegenerative diseases (Loihl and Murphy, 1998; Bolanos and Almeida, 1999; Liberatore et al., 1999).”
BackgroundNitric oxide and mitochondrial respiration
Brown, G. C. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00025-0 · Cited by 702 · see citing works
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Research works printed but not linked: 3
- Cambray-Deakin MA (1995) Cerebellar granule cells. In: Neuronal cell culture (Cohen J, Wilkin GP, eds), pp 3-13. New York: Oxford UP.
- McGeer PL, Schulzer M, McGeer EG (1996) Arthritis and anti- inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology 47:425-432.
- Schmidt HH, Kelm M (1996) Determination of nitrite and nitrate by Griess reaction. In: Methods in nitric oxide research (Feelisch M, Stamler JS, eds), pp 491-497. New York: Wiley.
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Self-citation
- Authors
- Bal-Price, A., & Brown, G. C.
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2001-09-01
- Volume
- 21
- Issue
- 17
- Pages
- 6480-6491
- ISSN
- 0270-6474
- 1529-2401
- Cited by
- 489
- References
- 2
- Language
- en
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