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Nuclear magnetic resonance imaging in multiple sclerosis
Abstract
Ten patients with definite multiple sclerosis underwent hydrogen nuclear magnetic resonance imaging with a 3.5 kilogauss superconducting magnet, using the inversion recovery and spin‐echo techniques of signal acquisition. Results were compared with high‐resolution x‐ray computed tomography. Spin‐echo images demonstrated abnormal regions as areas of variably increased signal intensity. The contrast between abnormal and normal white matter improved as the intervals between sequential radiofrequency pulses and between pulse administration and signal sampling were increased. Inversion recovery images demonstrated abnormal areas as regions of decreased signal intensity but did not visualize lesions as well as spin‐echo imaging. Spin‐echo and inversion recovery imaging each demonstrated more extensive abnormalities than did computed tomography.
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Citations
Cited by
Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis
Rao, S. M., Leo, G. J., Haughton, V. M., Aubin-Faubert, P. S., & Bernardin, L. (1989) · Neurology · doi:10.1212/wnl.39.2.161 · Cited by 516
Katz, D., Taubenberger, J. K., Cannella, B., McFarlin, D. E., Raine, C. S., & McFarland, H. F. (1993) · Annals of Neurology · doi:10.1002/ana.410340507 · Cited by 387
Miller, D. H., Barkhof, F., Berry, I., Kappos, L., Scotti, G., & Thompson, A. J. (1991) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.54.8.683 · Cited by 370
Kinkel, W. R. (1985) · Archives of Neurology · doi:10.1001/archneur.1985.04060090033010 · Cited by 257
Willoughby, E. W., Grochowski, E., Li, D. K. B., Oger, J., Kastrukoff, L. F., & Paty, D. W. (1989) · Annals of Neurology · doi:10.1002/ana.410250107 · Cited by 254
Metadata
- Authors
- Lukes, S. A., Crooks, L. E., Aminoff, M. J., Kaufman, L., Panitch, H. S., Mills, C., & Norman, D.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1983-06
- Volume
- 13
- Issue
- 6
- Pages
- 592-601
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2063059050
- Cited by
- 200
- References
- 0
- FWCI
- 17.64
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nuclear magnetic resonance imaging in multiple sclerosis. https://app.cochat.ai/papers/10.1002/ana.410130603
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- Lukes, S. A., Crooks, L. E., Aminoff, M. J., Kaufman, L., Panitch, H. S., Mills, C., & Norman, D. (1983). Nuclear magnetic resonance imaging in multiple sclerosis. Annals of Neurology. https://doi.org/10.1002/ana.410130603
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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