The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
High‐frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor
Abstract
Pharmacologic treatment for essential tremor and the tremor of Parkinson's disease is often inadequate. Stereotaxic surgery, such as thalamotomy, can effectively reduce tremors. We performed a multicenter trial of unilateral high‐frequency stimulation of the ventral intermedius nucleus of the thalamus in 29 patients with essential tremor and 24 patients with Parkinson's disease, using a blinded assessment at 3 months after surgery to compare clinical rating of tremor with stimulation ON with stimulation OFF and baseline and a 1‐year follow‐up. Six patients were not implanted because of lack of intraoperative tremor suppression (2 patients), hemorrhage (2 patients), withdrawal of consent (1 patient), and persistent microthalamotomy effect (1 patient). A significant reduction in both essential and parkinsonian tremor occurred contralaterally with stimulation. Patients reported a significant reduction in disability. Measures of function were significantly improved in patients with essential tremor. Complications related to surgery in implanted patients were few. Stimulation was commonly associated with transient paresthesias. Other adverse effects were mild and well tolerated. Efficacy was not reduced at 1 year. Chronic high‐frequency stimulation is safe and highly effective in ameliorating essential and parkinsonian tremor.
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Cites
Recent Developments in Parkinson's Disease
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Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus
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Leksell's posteroventral pallidotomy in the treatment of Parkinson's disease
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Effect of GPi pallidotomy on motor function in Parkinson's disease
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Self-citationStereotactic ventral pallidotomy for Parkinson's disease
Dogali, M., Fazzini, E., Kolodny, E., Eidelberg, D., Sterio, D., Devinsky, O., & Beric, A. (1995) · Neurology · doi:10.1212/wnl.45.4.753 · Cited by 394
Parkinson's disease and movement disorders
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Outcome after Stereotactic Thalamotomy for Parkinsonian, Essential, and Other Types of Tremor
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The relationship of essential tremor to other movement disorders: Report on 678 patients
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Cited by
A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor
Elias, W. J., Lipsman, N., Ondo, W. G., Ghanouni, P., Kim, Y. G., Lee, W., Schwartz, M., Hynynen, K., Lozano, A. M., Shah, B. B., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1600159 · Cited by 1,167
Probing and regulating dysfunctional circuits using deep brain stimulation
Lozano, A. M., & Lipsman, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.020 · Cited by 665
MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study
Lipsman, N., Schwartz, M. L., Huang, Y., Lee, L., Sankar, T., Chapman, M., Hynynen, K., & Lozano, A. M. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70048-6 · Cited by 604
Mechanisms of deep brain stimulation
Herrington, T. M., Cheng, J. J., & Eskandar, E. N. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00281.2015 · Cited by 551
History, Applications, and Mechanisms of Deep Brain Stimulation
Miocinovic, S., Somayajula, S., Chitnis, S., & Vitek, J. L. (2013) · JAMA Neurology · doi:10.1001/2013.jamaneurol.45 · Cited by 496
Metadata
- Authors
- Koller, W., Pahwa, R., Busenbark, K., Hubble, J., Wilkinson, S., Lang, A., Tuite, P., Sime, E., Lazano, A., Hauser, R., Malapira, T., Smith, D., Tarsy, D., Miyawaki, E., Norregaard, T., Kormos, T., & Olanow, C. W.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1997-09
- Volume
- 42
- Issue
- 3
- Pages
- 292-299
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2139071033
- Cited by
- 478
- References
- 25
- FWCI
- 15.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Koller, W., Pahwa, R., Busenbark, K., Hubble, J., Wilkinson, S., Lang, A., Tuite, P., Sime, E., Lazano, A., Hauser, R., Malapira, T., Smith, D., Tarsy, D., Miyawaki, E., Norregaard, T., Kormos, T., & Olanow, C. W. (1997). High‐frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor. Annals of Neurology. https://doi.org/10.1002/ana.410420304
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