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Highly Sensitive MRI Chemical Exchange Saturation Transfer Agents Using Liposomes

Aime, Silvio, Delli Castelli, Daniela, Terreno, Enzo·2005·Angewandte Chemie International Edition

Abstract

Contrasting views: Entrapment of a paramagnetic shift reagent for water protons inside liposomes dramatically improves the sensitivity of chemical exchange saturation transfer agents. The chemical shift of the water entrapped within the liposomes, relative to bulk water, depends upon the nature and concentration of the shift reagent as well as on the permeability of the liposome membrane (see picture; SR=shift reagent, Ln=lanthanide ion).

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Metadata

Authors
Aime, S., Delli Castelli, D., & Terreno, E.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2005-08-22
Volume
44
Issue
34
Pages
5513-5515
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2150548735
Cited by
201
References
0
FWCI
7.46
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Highly Sensitive MRI Chemical Exchange Saturation Transfer Agents Using Liposomes. https://app.cochat.ai/papers/10.1002/anie.200501473
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Aime, S., Delli Castelli, D., & Terreno, E. (2005). Highly Sensitive MRI Chemical Exchange Saturation Transfer Agents Using Liposomes. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200501473

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